Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5MJ6
DownloadVisualize
BU of 5mj6 by Molmil
Ligand-induced conformational change of Insulin-regulated aminopeptidase: insights on catalytic mechanism and active site plasticity.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ...
Authors:Mpakali, A, Stratikos, E, Saridakis, E, Giastas, P.
Deposit date:2016-11-30
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Ligand-Induced Conformational Change of Insulin-Regulated Aminopeptidase: Insights on Catalytic Mechanism and Active Site Plasticity.
J. Med. Chem., 60, 2017
7B6H
DownloadVisualize
BU of 7b6h by Molmil
Drosophila melanogaster TRAPP C11 subunits region 1 to 718
Descriptor: Trafficking protein particle complex subunit 11
Authors:Galindo, A, Munro, S, Planelles-Herrero, V.J, Degliesposti, G.
Deposit date:2020-12-07
Release date:2021-06-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
7B6E
DownloadVisualize
BU of 7b6e by Molmil
Drosophila melanogaster TRAPP C8 subunits region 355 to 661
Descriptor: FI18195p1
Authors:Galindo, A, Munro, S, Planelles-Herrero, V.J, Degliesposti, G.
Deposit date:2020-12-07
Release date:2021-06-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
7B6R
DownloadVisualize
BU of 7b6r by Molmil
Drosophila melanogaster TRAPPIII partial complex: core plus C8 and C11 attached region
Descriptor: FI18195p1, GEO08327p1, Probable trafficking protein particle complex subunit 2, ...
Authors:Galindo, A, Munro, S, Planelles-Herrero, V.J, Degliesposti, G.
Deposit date:2020-12-08
Release date:2021-06-09
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
7B6D
DownloadVisualize
BU of 7b6d by Molmil
Drosophila melanogaster TRAPPCore (C1, C2, C2L, C3a/b, C4, C5, C6 subunits)
Descriptor: GEO08327p1, Probable trafficking protein particle complex subunit 2, TRAPPC2L, ...
Authors:Galindo, A, Munro, S, Planelles-Herrero, V.J, Degliesposti, G.
Deposit date:2020-12-07
Release date:2021-06-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
7B70
DownloadVisualize
BU of 7b70 by Molmil
TRAPPCore plus C8 (355-596) and C11 (1-718) from MiniTRAPPIII
Descriptor: FI18195p1, GEO08327p1, Probable trafficking protein particle complex subunit 2, ...
Authors:Galindo, A, Munro, S, Planelles-Herrero, V.J.
Deposit date:2020-12-09
Release date:2021-06-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Embo J., 40, 2021
4Z7I
DownloadVisualize
BU of 4z7i by Molmil
Crystal structure of insulin regulated aminopeptidase in complex with ligand
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DG025 transition-state analogue enzyme inhibitor, ...
Authors:Mpakali, A, Saridakis, E, Harlos, K, Zhao, Y, Stratikos, E.
Deposit date:2015-04-07
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing.
J Immunol., 195, 2015
5AB2
DownloadVisualize
BU of 5ab2 by Molmil
Crystal structure of aminopeptidase ERAP2 with ligand
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mpakali, A, Giastas, P, Saridakis, E, Mavridis, I.M, Stratikos, E.
Deposit date:2015-07-31
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.729 Å)
Cite:Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (Er) Aminopeptidase 2.
J.Biol.Chem., 290, 2015
5AB0
DownloadVisualize
BU of 5ab0 by Molmil
Crystal structure of aminopeptidase ERAP2 with ligand
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mpakali, A, Giastas, P, Saridakis, E, Stratikos, E.
Deposit date:2015-07-31
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (Er) Aminopeptidase 2.
J.Biol.Chem., 290, 2015
7NUP
DownloadVisualize
BU of 7nup by Molmil
Endoplasmic reticulum aminopeptidase 2 complexed with a mixed hydroxamic and sulfonyl ligand
Descriptor: (3~{S})-4-(4-hydroxyphenyl)-~{N}-oxidanyl-3-[5-[[(5-phenylthiophen-2-yl)sulfonylamino]methyl]-1,2,3-triazol-1-yl]butanamide, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mpakali, A, Giastas, P, Stratikos, E.
Deposit date:2021-03-12
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Endoplasmic reticulum aminopeptidase 2 complexed with a mixed hydroxamic and sulfonyl ligand
To Be Published
7NSK
DownloadVisualize
BU of 7nsk by Molmil
Endoplasmic reticulum aminopeptidase 2 complexed with a hydroxamic ligand
Descriptor: (2~{S})-3-(4-hydroxyphenyl)-~{N}-oxidanyl-2-[4-[[(5-pyridin-2-ylthiophen-2-yl)sulfonylamino]methyl]-1,2,3-triazol-1-yl]propanamide, 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, ...
Authors:Mpakali, A, Giastas, P, Stratikos, E.
Deposit date:2021-03-08
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Endoplasmic reticulum aminopeptidase 2 in complex with a phosphinic ligand
To Be Published
1BX0
DownloadVisualize
BU of 1bx0 by Molmil
Ferredoxin:nadp+ oxidoreductase (ferredoxin reductase) mutant e312l
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ...
Authors:Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G.
Deposit date:1998-10-10
Release date:1998-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase.
J.Biol.Chem., 273, 1998
1BX1
DownloadVisualize
BU of 1bx1 by Molmil
FERREDOXIN:NADP+ OXIDOREDUCTASE (FERREDOXIN REDUCTASE) MUTANT E312Q
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ...
Authors:Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G.
Deposit date:1998-10-10
Release date:1998-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase.
J.Biol.Chem., 273, 1998
3BT7
DownloadVisualize
BU of 3bt7 by Molmil
Structure of E. coli 5-Methyluridine Methyltransferase TrmA in complex with 19 nucleotide T-arm analogue
Descriptor: RNA (5'-D(P*GP*CP*UP*GP*UP*GP*(5MU)P*UP*CP*GP*AP*UP*CP*CP*AP*CP*AP*GP*C)-3'), tRNA (uracil-5-)-methyltransferase
Authors:Alian, A, Stroud, R.M, Finer-Moore, J.
Deposit date:2007-12-27
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
8AA8
DownloadVisualize
BU of 8aa8 by Molmil
30S ribosomal protein S24e from Thermococcus barophilus
Descriptor: 30S ribosomal protein S24e
Authors:Calio, A, Hoh, F.
Deposit date:2022-06-30
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:30S ribosomal protein S24e from Thermococcus barophilus at 1.7A
To Be Published
8A8S
DownloadVisualize
BU of 8a8s by Molmil
30S ribosomal protein S24e from Thermococcus kodakarensis
Descriptor: 30S ribosomal protein S24e
Authors:Calio, A, Hoh, F.
Deposit date:2022-06-23
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.659 Å)
Cite:30S ribosomal protein S24e from Thermococcus kodakarensis
To Be Published
3DH3
DownloadVisualize
BU of 3dh3 by Molmil
Crystal Structure of RluF in complex with a 22 nucleotide RNA substrate
Descriptor: Ribosomal large subunit pseudouridine synthase F, stem loop fragment of E. Coli 23S RNA
Authors:Alian, A, DeGiovanni, A, Stroud, R.M, Finer-Moore, J.S.
Deposit date:2008-06-16
Release date:2009-04-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.
J.Mol.Biol., 388, 2009
4EOR
DownloadVisualize
BU of 4eor by Molmil
Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor NU6102
Descriptor: Cyclin-A2, Cyclin-dependent kinase 2, O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE
Authors:Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D.
Deposit date:2012-04-14
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
Chem.Biol., 19, 2012
4EON
DownloadVisualize
BU of 4eon by Molmil
Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with the inhibitor RO3306
Descriptor: (5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D.
Deposit date:2012-04-14
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
Chem.Biol., 19, 2012
4EOK
DownloadVisualize
BU of 4eok by Molmil
Thr 160 phosphorylated CDK2 H84S, Q85M, K89D - human cyclin A3 complex with the inhibitor NU6102
Descriptor: Cyclin-A2, Cyclin-dependent kinase 2, MONOTHIOGLYCEROL, ...
Authors:Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D.
Deposit date:2012-04-14
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
Chem.Biol., 19, 2012
4EOS
DownloadVisualize
BU of 4eos by Molmil
Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor RO3306
Descriptor: (5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Cyclin-A2, Cyclin-dependent kinase 2
Authors:Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D.
Deposit date:2012-04-14
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
Chem.Biol., 19, 2012
8P0I
DownloadVisualize
BU of 8p0i by Molmil
Crystal structure of the open conformation of insulin-regulated aminopeptidase in complex with a small-MW inhibitor
Descriptor: 2-[2-(3,5-dimethylpyrazol-1-yl)-6-(4-methoxyphenyl)pyrimidin-4-yl]oxy-N-methyl-N-[(2-methylpyridin-3-yl)methyl]ethanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mpakali, A, Giastas, P, Stratikos, E.
Deposit date:2023-05-10
Release date:2024-09-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Stabilization of the open conformation omicron f insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor.
Protein Sci., 33, 2024
4EOM
DownloadVisualize
BU of 4eom by Molmil
Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D.
Deposit date:2012-04-14
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
Chem.Biol., 19, 2012
4EOI
DownloadVisualize
BU of 4eoi by Molmil
Thr 160 phosphorylated CDK2 K89D, Q131E - human cyclin A3 complex with the inhibitor RO3306
Descriptor: (5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D.
Deposit date:2012-04-14
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
Chem.Biol., 19, 2012
4EOP
DownloadVisualize
BU of 4eop by Molmil
Thr 160 phosphorylated CDK2 Q131E - human cyclin A3 complex with the inhibitor RO3306
Descriptor: (5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D.
Deposit date:2012-04-14
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
Chem.Biol., 19, 2012

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon