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1TB7
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BU of 1tb7 by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With AMP
Descriptor: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, ...
Authors:Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
Deposit date:2004-05-19
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1TBF
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BU of 1tbf by Molmil
Catalytic Domain Of Human Phosphodiesterase 5A in Complex with Sildenafil
Descriptor: 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, GLYCEROL, MAGNESIUM ION, ...
Authors:Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
Deposit date:2004-05-20
Release date:2004-08-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1T9R
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BU of 1t9r by Molmil
Catalytic Domain Of Human Phosphodiesterase 5A
Descriptor: CITRIC ACID, PHOSPHATE ION, ZINC ION, ...
Authors:Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
Deposit date:2004-05-18
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1T9S
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BU of 1t9s by Molmil
Catalytic Domain Of Human Phosphodiesterase 5A in Complex with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ZINC ION, ...
Authors:Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
Deposit date:2004-05-18
Release date:2004-08-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1TBB
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BU of 1tbb by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Rolipram
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, ROLIPRAM, ...
Authors:Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
Deposit date:2004-05-19
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1TAZ
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BU of 1taz by Molmil
Catalytic Domain Of Human Phosphodiesterase 1B
Descriptor: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, MAGNESIUM ION, ZINC ION
Authors:Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
Deposit date:2004-05-19
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1TB5
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BU of 1tb5 by Molmil
Catalytic Domain Of Human Phosphodiesterase 4B In Complex With AMP
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ZINC ION, ...
Authors:Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
Deposit date:2004-05-19
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
5XG5
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BU of 5xg5 by Molmil
Crystal structure of Mitsuba-1 with bound NAcGal
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, MITSUBA-1
Authors:Terada, D, Voet, A.R.D, Kamata, K, Zhang, K.Y.J, Tame, J.R.H.
Deposit date:2017-04-12
Release date:2017-07-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Computational design of a symmetrical beta-trefoil lectin with cancer cell binding activity.
Sci Rep, 7, 2017
2A8D
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BU of 2a8d by Molmil
Haemophilus influenzae beta-carbonic anhydrase complexed with bicarbonate
Descriptor: BICARBONATE ION, Carbonic anhydrase 2, SULFATE ION, ...
Authors:Cronk, J.D, Rowlett, R.S, Zhang, K.Y.J, Tu, C, Endrizzi, J.A, Lee, J, Gareiss, P.C, Preiss, J.R.
Deposit date:2005-07-07
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase
Biochemistry, 45, 2006
2A8C
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BU of 2a8c by Molmil
Haemophilus influenzae beta-carbonic anhydrase
Descriptor: Carbonic anhydrase 2, SULFATE ION, ZINC ION
Authors:Cronk, J.D, Rowlett, R.S, Zhang, K.Y.J, Tu, C, Endrizzi, J.A, Lee, J, Gareiss, P.C, Preiss, J.R.
Deposit date:2005-07-07
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase
Biochemistry, 45, 2006
4YNX
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BU of 4ynx by Molmil
Structure of YdiE from E. coli
Descriptor: SULFATE ION, Uncharacterized protein YdiE
Authors:Tame, J.R.H, Nishimura, K, Zhang, K.Y.J.
Deposit date:2015-03-11
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal and solution structure of YdiE from Escherichia coli
Acta Crystallogr.,Sect.F, 71, 2015
4ZCN
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BU of 4zcn by Molmil
Crystal structure of nvPizza2-S16S58
Descriptor: IODIDE ION, SULFATE ION, nvPizza2-S16S58
Authors:Voet, A.R.D, Noguchi, H, Addy, C, Zhang, K.Y.J, Tame, J.R.H.
Deposit date:2015-04-16
Release date:2015-07-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of nvPizza2-S16S58
To Be Published
5CHB
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BU of 5chb by Molmil
Crystal structure of nvPizza2-S16H58 coordinating a CdCl2 nanocrystal
Descriptor: CADMIUM ION, CHLORIDE ION, SULFATE ION, ...
Authors:Voet, A.R.D, Noguchi, H, Addy, C, Zhang, K.Y.J, Tame, J.R.H.
Deposit date:2015-07-10
Release date:2015-07-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Biomineralization of a Cadmium Chloride Nanocrystal by a Designed Symmetrical Protein
Angew.Chem.Int.Ed.Engl., 54, 2015
1I6O
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BU of 1i6o by Molmil
CRYSTAL STRUCTURE OF E. COLI BETA CARBONIC ANHYDRASE (ECCA)
Descriptor: CARBONIC ANHYDRASE, ZINC ION
Authors:Cronk, J.D, Endrizzi, J.A, Cronk, M.R, O'Neill, J.W, Zhang, K.Y.J.
Deposit date:2001-03-02
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of E. coli beta-carbonic anhydrase, an enzyme with an unusual pH-dependent activity.
Protein Sci., 10, 2001
1I6P
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BU of 1i6p by Molmil
CRYSTAL STRUCTURE OF E. COLI BETA CARBONIC ANHYDRASE (ECCA)
Descriptor: CARBONIC ANHYDRASE, ZINC ION
Authors:Cronk, J.D, Endrizzi, J.A, Cronk, M.R, O'Neill, J.W, Zhang, K.Y.J.
Deposit date:2001-03-02
Release date:2001-05-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of E. coli beta-carbonic anhydrase, an enzyme with an unusual pH-dependent activity.
Protein Sci., 10, 2001
1Y2J
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BU of 1y2j by Molmil
Catalytic Domain Of Human Phosphodiesterase 4B In Complex With 3,5-dimethyl-1-(3-nitro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester
Descriptor: 3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ZINC ION, ...
Authors:Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-11-22
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Nat.Biotechnol., 23, 2005
1Y2D
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BU of 1y2d by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 1-(4-methoxy-phenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester
Descriptor: 1,2-ETHANEDIOL, 1-(4-METHOXYPHENYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-11-22
Release date:2005-03-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Nat.Biotechnol., 23, 2005
1Y2H
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BU of 1y2h by Molmil
Catalytic Domain Of Human Phosphodiesterase 4B In Complex With 1-(2-chloro-phenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester
Descriptor: 1-(2-CHLOROPHENYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ZINC ION, ...
Authors:Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-11-22
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Nat.Biotechnol., 23, 2005
1Y2B
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BU of 1y2b by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester
Descriptor: 1,2-ETHANEDIOL, 3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ...
Authors:Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-11-22
Release date:2005-03-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Nat.Biotechnol., 23, 2005
1Y2C
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BU of 1y2c by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 3,5-dimethyl-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester
Descriptor: 1,2-ETHANEDIOL, 3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ...
Authors:Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-11-22
Release date:2005-03-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Nat.Biotechnol., 23, 2005
1Y2K
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BU of 1y2k by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 3,5-dimethyl-1-(3-nitro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester
Descriptor: 1,2-ETHANEDIOL, 3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ...
Authors:Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-11-22
Release date:2005-03-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Nat.Biotechnol., 23, 2005
1Y2E
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BU of 1y2e by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 1-(4-amino-phenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester
Descriptor: 1,2-ETHANEDIOL, 1-(4-AMINOPHENYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ...
Authors:Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-11-22
Release date:2005-03-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Nat.Biotechnol., 23, 2005
2ESF
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BU of 2esf by Molmil
Identification of a Novel Non-Catalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase
Descriptor: BICARBONATE ION, Carbonic anhydrase 2, ZINC ION
Authors:Cronk, J.D, Rowlett, R.S, Zhang, K.Y.J, Tu, C, Endrizzi, J.A, Gareiss, P.C.
Deposit date:2005-10-26
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase.
Biochemistry, 45, 2006
1XOS
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BU of 1xos by Molmil
Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Sildenafil
Descriptor: 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, SULFATE ION, ...
Authors:Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-10-06
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004
1XOZ
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BU of 1xoz by Molmil
Catalytic Domain Of Human Phosphodiesterase 5A In Complex With Tadalafil
Descriptor: 6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE, MAGNESIUM ION, ZINC ION, ...
Authors:Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-10-07
Release date:2004-12-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004

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