1TBB

Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Rolipram

Summary for 1TBB

Entry DOI	10.2210/pdb1tbb/pdb
Related	1T9R 1T9S 1TAZ 1TB5 1TB7 1TBF
Descriptor	cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	pde4d, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm (By similarity): Q08499
Total number of polymer chains	2
Total formula weight	78013.61
Authors	Zhang, K.Y.J.,Card, G.L.,Suzuki, Y.,Artis, D.R.,Fong, D.,Gillette, S.,Hsieh, D.,Neiman, J.,West, B.L.,Zhang, C.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Bollag, G. (deposition date: 2004-05-19, release date: 2004-08-03, Last modification date: 2024-02-14)
Primary citation	Zhang, K.Y.J.,Card, G.L.,Suzuki, Y.,Artis, D.R.,Fong, D.,Gillette, S.,Hsieh, D.,Neiman, J.,West, B.L.,Zhang, C.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Bollag, G. A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases Mol.Cell, 15:279-286, 2004 Cited by PubMed: 15260978 DOI: 10.1016/j.molcel.2004.07.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation