1TB5
Catalytic Domain Of Human Phosphodiesterase 4B In Complex With AMP
Summary for 1TB5
Entry DOI | 10.2210/pdb1tb5/pdb |
Related | 1T9R 1T9S 1TAZ 1TB7 1TBB 1TBF |
Descriptor | cAMP-specific 3',5'-cyclic phosphodiesterase 4B, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | pde4b, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 88406.12 |
Authors | Zhang, K.Y.J.,Card, G.L.,Suzuki, Y.,Artis, D.R.,Fong, D.,Gillette, S.,Hsieh, D.,Neiman, J.,West, B.L.,Zhang, C.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Bollag, G. (deposition date: 2004-05-19, release date: 2004-08-03, Last modification date: 2024-02-14) |
Primary citation | Zhang, K.Y.J.,Card, G.L.,Suzuki, Y.,Artis, D.R.,Fong, D.,Gillette, S.,Hsieh, D.,Neiman, J.,West, B.L.,Zhang, C.,Milburn, M.V.,Kim, S.-H.,Schlessinger, J.,Bollag, G. A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases Mol.Cell, 15:279-286, 2004 Cited by PubMed: 15260978DOI: 10.1016/j.molcel.2004.07.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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