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1TB5

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With AMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
cAMP-specific 3',5'-cyclic phosphodiesterase 4Bpolymer38143766.12UniProt (Q07343)
Pfam (PF00233)
Homo sapiens (human)DPDE4, PDE32
2C, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, G
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4E, H
(A, B)
ADENOSINE MONOPHOSPHATEnon-polymer347.22Chemie (AMP)
5I, J
(A, B)
waterwater18.069Chemie (HOH)
Sequence modifications
A, B: 152 - 528 (UniProt: Q07343)
PDBExternal DatabaseDetails
Gly 148-expression tag
Ser 149-expression tag
His 150-expression tag
Met 151-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight87532.3
Non-Polymers*Number of molecules6
Total formula weight873.9
All*Total formula weight88406.1
*Water molecules are not included.

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PDB entries from 2025-06-25

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