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1W7X
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FACTOR7 - 413 COMPLEX
Descriptor:BLOOD COAGULATION FACTOR VIIA, GLYCEROL, CALCIUM ION, ...
Authors:Ackermann, J., Alig, L., Banner, D.W., Boehm, H.-J., Groebke-Zbinden, K., Hilpert, K., Lave, T., Kuehne, H., Obst-Sander, U., Riederer, M.A., Stahl, M., Tschopp, T.B., Weber, L., Wessel, H.P.
Deposit date:2004-09-14
Release date:2005-10-25
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Selective and Orally Bioavailable Phenylglycine Tissue Factor/Factor Viia Inhibitors.
Bioorg.Med.Chem.Lett., 15, 2005
1W8B
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FACTOR7 - 413 COMPLEX
Descriptor:BLOOD COAGULATION FACTOR VIIA, CALCIUM ION, (S)-[(R)-2-(4-BENZYLOXY-3-METHOXY-PHENYL)-2-(4-CARBAMIMIDOYL-PHENYLAMINO)-ACETYLAMINO]-PHENYL-ACETIC ACID
Authors:Ackermann, J., Alig, L., Banner, D.W., Boehm, H.-J., Groebke-Zbinden, K., Hilpert, K., Lave, T., Kuehne, H., Obst-Sander, U., Riederer, M.A., Stahl, M., Tschopp, T.B., Weber, L., Wessel, H.P.
Deposit date:2004-09-17
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Selective and Orally Bioavailable Phenylglycine Tissue Factor/Factor Viia Inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
1W0Y
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TF7A_3771 COMPLEX
Descriptor:BLOOD COAGULATION FACTOR VIIA, TISSUE FACTOR, 4-(4-BENZYLOXY-2-METHANESULFONYLAMINO-5-METHOXY-BENZYLAMINO)-BENZAMIDINE, ...
Authors:Banner, D.W., D'Arcy, A., Groebke-Zbinden, K., Ackermann, J., Kirchhofer, D., Ji, Y.-H., Tschopp, T.B., Wallbaum, S., Weber, L.
Deposit date:2004-05-27
Release date:2005-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Design of Selective Phenylglycine Amide Tissue Factor/Factor Viia Inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
1W2K
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TF7A_4380 COMPLEX
Descriptor:BLOOD COAGULATION FACTOR VIIA, TISSUE FACTOR, (2R)-2-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO)-N-BENZYL-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE, ...
Authors:Banner, D.W., D'Arcy, A., Groebke-Zbinden, K., Ackermann, J., Kirchhofer, D., Ji, Y.-H., Tschopp, T.B., Wallbaum, S., Weber, L.
Deposit date:2004-07-06
Release date:2005-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Design of Selective Phenylglycine Amide Tissue Factor/Factor Viia Inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
2BZ6
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ORALLY AVAILABLE FACTOR7A INHIBITOR
Descriptor:BLOOD COAGULATION FACTOR VIIA, (R)-(4-CARBAMIMIDOYL-PHENYLAMINO)-[5-ETHOXY-2-FLUORO-3-[(R)-TETRAHYDRO-FURAN-3-YLOXY]-PHENYL]-ACETIC ACID, SULFATE ION, ...
Authors:Groebke-Zbinden, K., Obst-Sander, U., Hilpert, K., Kuehne, H., Banner, D.W., Boehm, H.J., Stahl, M., Ackermann, J., Alig, L., Weber, L., Wessel, H.P., Riederer, M.A., Tschopp, T.B., Lave, T.
Deposit date:2005-08-11
Release date:2006-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Dose-Dependant Antithrombotic Activity of an Orally Active Tissue Factor/Factor Viia Inhibitor without Concomitant Enhancement of Bleeding Propensity.
Bioorg.Med.Chem., 14, 2006
2Z5S
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MOLECULAR BASIS FOR THE INHIBITION OF P53 BY MDMX
Descriptor:Mdm4 protein, Cellular tumor antigen p53
Authors:Popowicz, G.M., Czarna, A., Rothweiler, U., Szwagierczak, A., Holak, T.A.
Deposit date:2007-07-17
Release date:2007-11-06
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis for the inhibition of p53 by Mdmx.
Cell Cycle, 6, 2007
2Z5T
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MOLECULAR BASIS FOR THE INHIBITION OF P53 BY MDMX
Descriptor:Mdm4 protein, Cellular tumor antigen p53
Authors:Popowicz, G.M., Czarna, A., Rothweiler, U., Szwagierczak, A., Holak, T.A.
Deposit date:2007-07-17
Release date:2007-11-06
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis for the inhibition of p53 by Mdmx.
Cell Cycle, 6, 2007