2Z5S
Molecular basis for the inhibition of p53 by Mdmx
Summary for 2Z5S
Entry DOI | 10.2210/pdb2z5s/pdb |
Related | 1ycr 2cr8 2Z5T |
Descriptor | Mdm4 protein, Cellular tumor antigen p53 (3 entities in total) |
Functional Keywords | mdmx, mdm4, p53, acetylation, activator, anti-oncogene, apoptosis, cell cycle, cytoplasm, disease mutation, dna-binding, endoplasmic reticulum, nucleus, phosphorylation, polymorphism, transcription regulation |
Biological source | Danio rerio (zebrafish) More |
Total number of polymer chains | 6 |
Total formula weight | 52408.76 |
Authors | Popowicz, G.M.,Czarna, A.,Rothweiler, U.,Szwagierczak, A.,Holak, T.A. (deposition date: 2007-07-17, release date: 2007-11-06, Last modification date: 2023-11-01) |
Primary citation | Popowicz, G.M.,Czarna, A.,Rothweiler, U.,Szwagierczak, A.,Krajewski, M.,Weber, L.,Holak, T.A. Molecular basis for the inhibition of p53 by Mdmx. Cell Cycle, 6:2386-2392, 2007 Cited by PubMed: 17938582DOI: 10.4161/cc.6.19.4740 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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