Author results

1DSY
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C2 DOMAIN FROM PROTEIN KINASE C (ALPHA) COMPLEXED WITH CA2+ AND PHOSPHATIDYLSERINE
Descriptor:PROTEIN KINASE C, ALPHA TYPE, CALCIUM ION, ...
Authors:Verdaguer, N., Corbalan-Garcia, S., Ochoa, W.F., Fita, I., Gomez-Fernandez, J.C.
Deposit date:2000-01-10
Release date:2000-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.
EMBO J., 18, 1999
1FPN
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HUMAN RHINOVIRUS SEROTYPE 2 (HRV2)
Descriptor:COAT PROTEIN VP1, COAT PROTEIN VP2, COAT PROTEIN VP3, ...
Authors:Verdaguer, N., Blaas, D., Fita, I.
Deposit date:2000-08-31
Release date:2000-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human rhinovirus serotype 2 (HRV2).
J.Mol.Biol., 300, 2000
1MQT
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SWINE VESICULAR DISEASE VIRUS COAT PROTEIN
Descriptor:Polyprotein, Polyprotein Capsid Protein, OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE
Authors:Verdaguer, N., Jimenez-Clavero, M.A., Fita, I., Ley, V.
Deposit date:2002-09-17
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:STRUCTURE OF SWINE VESICULAR DISEASE VIRUS: MAPPING OF CHANGES OCCURRING DURING ADAPTATION OF HUMAN COXSACKIE B5 VIRUS TO INFECT SWINE
J.Virol., 77, 2003
1V9U
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HUMAN RHINOVIRUS 2 BOUND TO A FRAGMENT OF ITS CELLULAR RECEPTOR PROTEIN
Descriptor:Coat protein VP1, Coat protein VP2, Coat protein VP3, ...
Authors:Verdaguer, N., Fita, I., Reithmayer, M., Moser, R., Blaas, D.
Deposit date:2004-02-03
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:X-ray structure of a minor group human rhinovirus bound to a fragment of its cellular receptor protein
NAT.STRUCT.MOL.BIOL., 11, 2004
2D47
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MOLECULAR STRUCTURE OF A COMPLETE TURN OF A-DNA
Descriptor:DNA (5'-D(*CP*CP*CP*CP*CP*GP*CP*GP*GP*GP*GP*G)-3'), SPERMINE
Authors:Verdaguer, N., Aymami, J., Fernandez-Forner, D., Fita, I., Coll, M., Huynh-Dinh, T., Igolen, J., Subirana, J.A.
Deposit date:1991-10-02
Release date:1991-10-02
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular structure of a complete turn of A-DNA.
J.Mol.Biol., 221, 1991
4WZM
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MUTANT K18E OF RNA DEPENDENT RNA POLYMERASE FROM FOOT-AND-MOUTH DISEASE VIRUS COMPLEXED WITH RNA
Descriptor:RNA dependent RNA polymerase, RNA template, RNA primer, ...
Authors:Verdaguer, N., Ferrer-Orta, C., de la Higuera, N.
Deposit date:2014-11-20
Release date:2015-05-06
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
4Y2C
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M300V 3D POLYMERASE MUTANT OF EMCV
Descriptor:Genome polyprotein, GLYCEROL
Authors:Verdaguer, N., Ferrer-Orta, C., Vives-Adrian, L.
Deposit date:2015-02-09
Release date:2015-04-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y3C
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I304V 3D POLYMERASE MUTANT OF EMCV
Descriptor:3D polymerase, GLYCEROL, CHLORIDE ION
Authors:Verdaguer, N., Ferrer-Orta, C., Vives-Adrian, L.
Deposit date:2015-02-10
Release date:2015-04-01
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4LT7
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CRYSTAL STRUCTURE OF THE C2A DOMAIN OF RABPHILIN-3A IN COMPLEX WITH A CALCIUM
Descriptor:Rabphilin-3A, CALCIUM ION
Authors:Verdaguer, N., Ferrer-Orta, C., Buxaderas, M., Corbalan-Garcia, S., Perez-Sanchez, D., Guerrero-Valero, M., Luengo, G., Pous, J., Guerra, P., Gomez-Fernandez, J.C., Guillen, J.
Deposit date:2013-07-23
Release date:2013-12-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4WZQ
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MUTANT K20E OF RNA DEPENDENT RNA POLYMERASE 3D FROM FOOT-AND-MOUTH DISEASE VIRUS COMPLEXED WITH RNA
Descriptor:RNA dependent-RNA polymerase 3D, RNA template, RNAprimer, ...
Authors:Verdaguer, N., Ferrer-Orta, C.
Deposit date:2014-11-20
Release date:2015-05-06
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
4X2B
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K20A RNA DEPENDENT RNA POLYMERASE MUTANT FROM FOOT-AND-MOUTH DISEASE VIRUS COMPLEXED WITH AN RNA
Descriptor:RNA dependent RNA polymerase, RNA template, RNA primer, ...
Authors:Verdaguer, N., Ferrer-Orta, C.
Deposit date:2014-11-26
Release date:2015-05-06
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
5JXS
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MUTANT GC216/7AA OF 3D POLYMERASE FROM FOOT-AND-MOUTH DISEASE VIRUS
Descriptor:RNA dependent RNA polymerase, RNA Template, RNA Primer, ...
Authors:Verdaguer, N., Ferrer-Orta, C.
Deposit date:2016-05-13
Release date:2016-06-01
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J.Virol., 90, 2016
5LOW
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STRUCTURE OF THE CA2+-BOUND RABPHILIN 3A C2B DOMAIN SNAP25 COMPLEX (P21 SPACE GROUP)
Descriptor:Rabphilin-3A, Synaptosomal-associated protein 25, GLYCEROL, ...
Authors:Verdaguer, N., Ferrer-Orta, C.
Deposit date:2016-08-10
Release date:2017-06-21
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6GVV
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MUTANT M16A OF RNA DEPENDENT RNA POLYMERASE 3D FROM FOOT-AND-MOUTH DISEASE VIRUS
Descriptor:RNA polymerase 3D, GLYCEROL
Authors:Verdaguer, N., Ferrer Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J.Virol., 92, 2018
6GVY
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MUTANT M16A OF RNA DEPENDENT RNA POLYMERASE 3D FROM FOOT-AND-MOUTH DISEASE VIRUS COMPLEXED WITH AN TEMPLATE -PRIMER RNA
Descriptor:Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), RNA (5'-R(P*CP*UP*CP*CP*CP*GP*GP*G)-3'), ...
Authors:Verdaguer, N., Ferrer-Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J. Virol., 92, 2018
6S2L
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FMDV 3D POLYMERASE CRYSTALLIZED IN PRESENCE OF (F)URIDYLYLATED VPG PEPTIDE
Descriptor:Genome polyprotein, GLYCEROL
Authors:Verdaguer, N., Ferrer-Orta, C.
Deposit date:2019-06-21
Release date:2019-07-03
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase.
Molecules, 24, 2019
2E9R
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FOOT-AND-MOUTH DISEASE VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH A TEMPLATE-PRIMER RNA AND WITH RIBAVIRIN
Descriptor:5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3', RNA-dependent RNA polymerase, ...
Authors:Ferrer-Orta, C., Arias, A., Perez-Luque, R., Escarmis, C., Domingo, E., Verdaguer, N.
Deposit date:2007-01-26
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E9T
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FOOT-AND-MOUTH DISEASE VIRUS RNA-POLYMERASE RNA DEPENDENT IN COMPLEX WITH A TEMPLATE-PRIMER RNA AND 5F-UTP
Descriptor:5'-R(P*UP*AP*GP*GP*GP*CP*CP*C)-3', 5'-R(*GP*GP*GP*CP*CP*CP*(5FU))-3', RNA-dependent RNA polymerase, ...
Authors:Ferrer-Orta, C., Arias, A., Perez-Luque, R., Escarmis, C., Domingo, E., Verdaguer, N.
Deposit date:2007-01-26
Release date:2007-06-26
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
2EC0
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RNA-DEPENDENT RNA POLYMERASE OF FOOT-AND-MOUTH DISEASE VIRUS IN COMPLEX WITH A TEMPLATE-PRIMER RNA AND ATP
Descriptor:5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', RNA-dependent RNA polymerase, ...
Authors:Ferrer-Orta, C., Arias, A., Perez-Luque, R., Escarmis, C., Domingo, E., Verdaguer, N.
Deposit date:2007-02-09
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
2D7S
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FOOT AND MOUTH DISEASE VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH VPG PROTEIN
Descriptor:RNA-dependent RNA polymerase, VPg1 protein
Authors:Ferrer-Orta, C., Arias, A., Perez-Luque, R., Escarmis, C., Domingo, E., Verdaguer, N.
Deposit date:2005-11-29
Release date:2006-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of a protein primer-polymerase complex in the initiation of genome replication
Embo J., 25, 2006
2F8E
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FOOT AND MOUTH DISEASE VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH URIDYLYLATED VPG PROTEIN
Descriptor:RNA-dependent RNA polymerase, VPg protein, MAGNESIUM ION, ...
Authors:Ferrer-Orta, C., Arias, A., Perez-Luque, R., Escarmis, C., Domingo, E., Verdaguer, N.
Deposit date:2005-12-02
Release date:2006-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of a protein primer-polymerase complex in the initiation of genome replication
Embo J., 25, 2006
4WZN
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CRYSTAL STRUCTURE OF THE 2B PROTEIN SOLUBLE DOMAIN FROM HEPATITIS A VIRUS
Descriptor:Genome polyprotein, GLYCEROL
Authors:Garriga, D., Vives-Adrian, L., Buxaderas, M., Ferreira-da-Silva, F., Almeida, B., Macedo-Ribeiro, S., Pereira, P.J., Verdaguer, N.
Deposit date:2014-11-20
Release date:2015-01-28
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Host Membrane Remodeling Induced by Protein 2B of Hepatitis A Virus.
J.Virol., 89, 2015
3FBM
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D431N MUTANT VP2 PROTEIN OF INFECTIOUS BURSAL DISEASE VIRUS; DERIVED T=1 PARTICLES
Descriptor:Polyprotein, CALCIUM ION
Authors:Irigoyen, N., Garriga, D., Navarro, A., Verdaguer, N., Rodriguez, J.F., Caston, J.R.
Deposit date:2008-11-19
Release date:2009-01-13
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Autoproteolytic Activity Derived from the Infectious Bursal Disease Virus Capsid Protein
J.Biol.Chem., 284, 2009
5M2X
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CRYSTAL STRUCTURE OF THE FULL-LENGTH ZIKA VIRUS NS5 PROTEIN (HUMAN ISOLATE Z1106033)
Descriptor:NS5, S-ADENOSYL-L-HOMOCYSTEINE, PHOSPHATE ION, ...
Authors:Ferrero, D.S., Ruiz-Arroyo, V.M., Soler, N., Uson, I., Verdaguer, N.
Deposit date:2016-10-13
Release date:2018-06-06
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (4.991 Å)
Cite:Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
5M2Z
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CRYSTAL STRUCTURE OF THE FULL-LENGTH ZIKA VIRUS NS5 PROTEIN (HUMAN ISOLATE Z1106033)
Descriptor:NS5, PHOSPHATE ION, ZINC ION, ...
Authors:Ferrero, D.S., Ruiz-Arroyo, V.M., Soler, N., Uson, I., Verdaguer, N.
Deposit date:2016-10-13
Release date:2018-06-06
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019