Author results

2X72
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CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE.
Descriptor:RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Standfuss, J., Edwards, P.C., Dantona, A., Fransen, M., Xie, G., Oprian, D.D., Schertler, G.F.X.
Deposit date:2010-02-22
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin
Nature, 471, 2011
2BHW
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PEA LIGHT-HARVESTING COMPLEX II AT 2.5 ANGSTROM RESOLUTION
Descriptor:CHLOROPHYLL A-B BINDING PROTEIN AB80, (3R,3'R,6'S,9R,9'R,13R,13'S)-4',5'-DIDEHYDRO-5',6',7',8',9,9',10,10',11,11',12,12',13,13',14,14',15,15'-OCTADECAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, ...
Authors:Standfuss, J., Terwisscha van Scheltinga, A.C., Lamborghini, M., Kuehlbrandt, W.
Deposit date:2005-01-19
Release date:2006-05-23
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanisms of Photoprotection and Nonphotochemical Quenching in Pea Light-Harvesting Complex at 2.5 A Resolution.
Embo J., 24, 2005
2J4Y
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CRYSTAL STRUCTURE OF A RHODOPSIN STABILIZING MUTANT EXPRESSED IN MAMMALIAN CELLS
Descriptor:RHODOPSIN, RETINAL, N-ACETYL-D-GLUCOSAMINE
Authors:Standfuss, J., Xie, G., Edwards, P.C., Burghammer, M., Oprian, D.D., Schertler, G.F.X.
Deposit date:2006-09-07
Release date:2007-09-25
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of a Thermally Stable Rhodopsin Mutant.
J.Mol.Biol., 372, 2007
4A4M
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CRYSTAL STRUCTURE OF THE LIGHT-ACTIVATED CONSTITUTIVELY ACTIVE N2C, M257Y,D282C RHODOPSIN MUTANT IN COMPLEX WITH A PEPTIDE RESEMBLING THE C-TERMINUS OF THE GALPHA-PROTEIN SUBUNIT (GACT)
Descriptor:RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3, RETINAL, ...
Authors:Deupi, X., Edwards, P., Singhal, A., Nickle, B., Oprian, D.D., Schertler, G.F.X., Standfuss, J.
Deposit date:2011-10-17
Release date:2012-01-25
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Stabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II.
Proc.Natl.Acad.Sci.USA, 109, 2012
5J7A
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BACTERIORHODOPSIN GROUND STATE STRUCTURE OBTAINED WITH SERIAL FEMTOSECOND CRYSTALLOGRAPHY
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL
Authors:Nogly, P., Panneels, V., Nelson, G., Gati, C., Kimura, T., Milne, C., Milathianaki, D., Kubo, M., Wu, W., Conrad, C., Coe, J., Bean, R., Zhao, Y., Bath, P., Dods, R., Harimoorthy, R., Beyerlein, K.R., Rheinberger, J., James, D., DePonte, D., Li, C., Sala, L., Williams, G., Hunter, M., Koglin, J.E., Berntsen, P., Nango, E., Iwata, S., Chapman, H.N., Fromme, P., Frank, M., Abela, R., Boutet, S., Barty, A., White, T.A., Weierstall, U., Spence, J., Neutze, R., Schertler, G., Standfuss, J.
Deposit date:2016-04-06
Release date:2016-08-31
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography.
Nat Commun, 7, 2016
4ZWJ
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CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO ARRESTIN BY FEMTOSECOND X-RAY LASER
Descriptor:Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
Authors:Kang, Y., Zhou, X.E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., White, T.A., Yefanov, O., Han, G.W., Xu, Q., de Waal, P.W., Ke, J., Tan, M.H.E., Zhang, C., Moeller, A., West, G.M., Pascal, B., Eps, N.V., Caro, L.N., Vishnivetskiy, S.A., Lee, R.J., Suino-Powell, K.M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G.J., Messerschmidt, M., Gati, C., Zatsepin, N.A., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C.S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H.N., Spence, J.C.H., Fromme, P., Weierstall, U., Ernst, O.P., Katritch, V., Gurevich, V.V., Griffin, P.R., Hubbell, W.L., Stevens, R.C., Cherezov, V., Melcher, K., Xu, H.E., GPCR Network (GPCR)
Deposit date:2015-05-19
Release date:2015-07-29
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
4X31
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ROOM TEMPERATURE STRUCTURE OF BACTERIORHODOPSIN FROM LIPIDIC CUBIC PHASE OBTAINED WITH SERIAL MILLISECOND CRYSTALLOGRAPHY USING SYNCHROTRON RADIATION
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL
Authors:Nogly, P., James, D., Wang, D., White, T., Zatsepin, N., Shilova, A., Nelson, G., Liu, H., Johansson, L., Heymann, M., Jaeger, K., Metz, M., Wickstrand, C., Wu, W., Baath, P., Berntsen, P., Oberthuer, D., Panneels, V., Cherezov, V., Chapman, H., Spence, J., Schertler, G., Neutze, R., Moraes, I., Burghammer, M., Standfuss, J., Weierstall, U.
Deposit date:2014-11-27
Release date:2015-02-18
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Lipidic cubic phase serial millisecond crystallography using synchrotron radiation.
Iucrj, 2, 2015
6FUF
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CRYSTAL STRUCTURE OF THE RHODOPSIN-MINI-GO COMPLEX
Descriptor:Rhodopsin, Guanine nucleotide-binding protein G(o) subunit alpha, RETINAL, ...
Authors:Tsai, C.-J., Weinert, T., Muehle, J., Pamula, F., Nehme, R., Flock, T., Nogly, P., Edwards, P.C., Carpenter, B., Gruhl, T., Ma, P., Deupi, X., Standfuss, J., Tate, C.G., Schertler, G.F.X.
Deposit date:2018-02-27
Release date:2018-10-03
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (3.117 Å)
Cite:Crystal structure of rhodopsin in complex with a mini-Gosheds light on the principles of G protein selectivity.
Sci Adv, 4, 2018
6G7H
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: RESTING STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6G7I
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: 49-406 FS STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6G7J
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: 457-646 FS STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6G7K
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: 10 PS STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6G7L
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: 8.3 MS STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6QZH
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STRUCTURE OF THE HUMAN CC CHEMOKINE RECEPTOR 7 IN COMPLEX WITH THE INTRACELLULAR ALLOSTERIC ANTAGONIST CMP2105 AND THE INSERTION PROTEIN SIALIDASE NANA
Descriptor:C-C chemokine receptor type 7,Sialidase A,C-C chemokine receptor type 7, TRIETHYLENE GLYCOL, 3-[[4-[[(1~{R})-2,2-dimethyl-1-(5-methylfuran-2-yl)propyl]amino]-1,1-bis(oxidanylidene)-1,2,5-thiadiazol-3-yl]amino]-~{N},~{N},6-trimethyl-2-oxidanyl-benzamide, ...
Authors:Jaeger, K., Bruenle, S., Weinert, T., Guba, W., Muehle, J., Miyazaki, T., Weber, M., Furrer, A., Haenggi, N., Tetaz, T., Huang, C.Y., Mattle, D., Vonach, J.M., Gast, A., Kuglstatter, A., Rudolph, M.G., Nogly, P., Benz, J., Dawson, R.J.P., Standfuss, J.
Deposit date:2019-03-11
Release date:2019-09-04
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7.
Cell, 178, 2019
4X32
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BACTERIORHODOPSIN GROUND STATE STRUCTURE COLLECTED IN CRYO CONDITIONS FROM CRYSTALS OBTAINED IN LCP WITH PEG AS A PRECIPITANT.
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL
Authors:Nogly, P., Standfuss, J.
Deposit date:2014-11-27
Release date:2015-02-18
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Lipidic cubic phase serial millisecond crystallography using synchrotron radiation.
Iucrj, 2, 2015
6FK6
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CRYSTAL STRUCTURE OF N2C/D282C STABILIZED OPSIN BOUND TO RS01
Descriptor:Rhodopsin, PALMITIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mattle, D., Standfuss, J., Dawson, R.
Deposit date:2018-01-23
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FK7
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CRYSTAL STRUCTURE OF N2C/D282C STABILIZED OPSIN BOUND TO RS06
Descriptor:Rhodopsin, PALMITIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mattle, D., Standfuss, J., Dawson, R.
Deposit date:2018-01-23
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FK8
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CRYSTAL STRUCTURE OF N2C/D282C STABILIZED OPSIN BOUND TO RS08
Descriptor:Rhodopsin, PALMITIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mattle, D., Standfuss, J., Dawson, R.
Deposit date:2018-01-23
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FK9
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CRYSTAL STRUCTURE OF N2C/D282C STABILIZED OPSIN BOUND TO RS09
Descriptor:Rhodopsin, PALMITIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mattle, D., Standfuss, J., Dawson, R.
Deposit date:2018-01-23
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FKA
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CRYSTAL STRUCTURE OF N2C/D282C STABILIZED OPSIN BOUND TO RS11
Descriptor:Rhodopsin, PALMITIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mattle, D., Standfuss, J., Dawson, R.
Deposit date:2018-01-23
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FKB
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CRYSTAL STRUCTURE OF N2C/D282C STABILIZED OPSIN BOUND TO RS13
Descriptor:Rhodopsin, PALMITIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mattle, D., Standfuss, J., Dawson, R.
Deposit date:2018-01-23
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FKC
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CRYSTAL STRUCTURE OF N2C/D282C STABILIZED OPSIN BOUND TO RS15
Descriptor:Rhodopsin, PALMITIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mattle, D., Standfuss, J., Dawson, R.
Deposit date:2018-01-23
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FKD
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CRYSTAL STRUCTURE OF N2C/D282C STABILIZED OPSIN BOUND TO RS16
Descriptor:Rhodopsin, PALMITIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mattle, D., Standfuss, J., Dawson, R.
Deposit date:2018-01-23
Release date:2018-04-04
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Ligand channel in pharmacologically stabilized rhodopsin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2WTR
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FULL LENGTH ARRESTIN2
Descriptor:BETA-ARRESTIN-1, BARIUM ION
Authors:Zhou, H.G., Standfuss, J., Watson, K.A., Krasel, C.
Deposit date:2009-09-21
Release date:2009-09-29
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A New Dimeric Crystal Form for Arrestin2
To be Published
4BEY
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NIGHT BLINDNESS CAUSING G90D RHODOPSIN IN COMPLEX WITH GACT2 PEPTIDE
Descriptor:Rhodopsin, Guanine nucleotide-binding protein G(t) subunit alpha-1, SULFATE ION, ...
Authors:Singhal, A., Ostermaier, M.K., Vishnivetskiy, S.A., Panneels, V., Homan, K.T., Tesmer, J.J.G., Veprintsev, D., Deupi, X., Gurevich, V.V., Schertler, G.F.X., Standfuss, J.
Deposit date:2013-03-12
Release date:2013-05-08
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin.
Embo Rep., 14, 2013
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