7YYY
Molecular snapshots of drug release from tubulin: 1 microsecond after photoactivation
Summary for 7YYY
Entry DOI | 10.2210/pdb7yyy/pdb |
Descriptor | Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed Ankyrin Repeat Protein (DARPIN) D1, ... (9 entities in total) |
Functional Keywords | time-resolved serial crystallography, tubulin dynamics, azobenzene dynamics, cell cycle |
Biological source | synthetic construct More |
Total number of polymer chains | 3 |
Total formula weight | 119621.86 |
Authors | Wranik, M.,Weinert, T.,Standfuss, J. (deposition date: 2022-02-18, release date: 2023-02-22, Last modification date: 2023-09-27) |
Primary citation | Wranik, M.,Weinert, T.,Slavov, C.,Masini, T.,Furrer, A.,Gaillard, N.,Gioia, D.,Ferrarotti, M.,James, D.,Glover, H.,Carrillo, M.,Kekilli, D.,Stipp, R.,Skopintsev, P.,Brunle, S.,Muhlethaler, T.,Beale, J.,Gashi, D.,Nass, K.,Ozerov, D.,Johnson, P.J.M.,Cirelli, C.,Bacellar, C.,Braun, M.,Wang, M.,Dworkowski, F.,Milne, C.,Cavalli, A.,Wachtveitl, J.,Steinmetz, M.O.,Standfuss, J. Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography. Nat Commun, 14:903-903, 2023 Cited by PubMed: 36807348DOI: 10.1038/s41467-023-36481-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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