Author results

4RNP
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BACTERIOPHAGE T7 RNA POLYMERASE, HIGH SALT CRYSTAL FORM, LOW TEMPERATURE DATA, ALPHA-CARBONS ONLY
Descriptor:RNA POLYMERASE
Authors:Liu, Z.J., Sousa, R., Rose, J.P., Wang, B.C.
Deposit date:1997-09-11
Release date:1997-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of bacteriophage T7 RNA polymerase at 3.3 A resolution.
Nature, 364, 1993
1NZ6
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CRYSTAL STRUCTURE OF AUXILIN J-DOMAIN
Descriptor:Auxilin
Authors:Jiang, J., Taylor, A.B., Prasad, K., Ishikawa-Brush, Y., Hart, P.J., Lafer, E.M., Sousa, R.
Deposit date:2003-02-16
Release date:2003-04-22
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-function analysis of the auxilin J-domain reveals an extended Hsc70 interaction interface.
Biochemistry, 42, 2003
1YUW
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CRYSTAL STRUCTURE OF BOVINE HSC70(AA1-554)E213A/D214A MUTANT
Descriptor:Heat shock cognate 71 kDa protein
Authors:Jiang, J., Lafer, E.M., Prasad, K., Sousa, R.
Deposit date:2005-02-14
Release date:2005-10-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of interdomain communication in the Hsc70 chaperone
Mol.Cell, 20, 2005
2QW9
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CRYSTAL STRUCTURE OF BOVINE HSC70 (1-394AA)IN THE APO STATE
Descriptor:Heat shock cognate 71 kDa protein, GLYCEROL
Authors:Jiang, J., Maes, E.G., Wang, L., Taylor, A.B., Hinck, A.P., Lafer, E.M., Sousa, R.
Deposit date:2007-08-10
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
2QWL
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CRYSTAL STRUCTURE OF BOVINE HSC70 (1-394AA)IN THE ADP STATE
Descriptor:Heat shock cognate 71 kDa protein, MAGNESIUM ION, SODIUM ION, ...
Authors:Jiang, J., Maes, E.G., Wang, L., Taylor, A.B., Hinck, A.P., Lafer, E.M., Sousa, R.
Deposit date:2007-08-10
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
2QWM
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CRYSTAL STRUCTURE OF BOVINE HSC70 (1-394AA)IN THE ADP*VI STATE
Descriptor:Heat shock cognate 71 kDa protein, MAGNESIUM ION, SODIUM ION, ...
Authors:Jiang, J., Maes, E.G., Wang, L., Taylor, A.B., Hinck, A.P., Lafer, E.M., Sousa, R.
Deposit date:2007-08-10
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
2QWN
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CRYSTAL STRUCTURE OF DISULFIDE-BOND-CROSSLINKED COMPLEX OF BOVINE HSC70 (1-386AA)R171C AND BOVINE AUXILIN (810-910AA)D876C IN THE ADP*PI STATE
Descriptor:Heat shock cognate 71 kDa protein, Putative tyrosine-protein phosphatase auxilin, PHOSPHATE ION, ...
Authors:Jiang, J., Maes, E.G., Wang, L., Taylor, A.B., Hinck, A.P., Lafer, E.M., Sousa, R.
Deposit date:2007-08-10
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
2QWO
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CRYSTAL STRUCTURE OF DISULFIDE-BOND-CROSSLINKED COMPLEX OF BOVINE HSC70 (1-394AA)R171C AND BOVINE AUXILIN (810-910AA)D876C IN THE ADP*PI FORM #1
Descriptor:Heat shock cognate 71 kDa protein, Putative tyrosine-protein phosphatase auxilin, PHOSPHATE ION, ...
Authors:Jiang, J., Maes, E.G., Wang, L., Taylor, A.B., Hinck, A.P., Lafer, E.M., Sousa, R.
Deposit date:2007-08-10
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
2QWP
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CRYSTAL STRUCTURE OF DISULFIDE-BOND-CROSSLINKED COMPLEX OF BOVINE HSC70 (1-394AA)R171C AND BOVINE AUXILIN (810-910AA)D876C IN THE ADP*PI FORM #2
Descriptor:Heat shock cognate 71 kDa protein, Putative tyrosine-protein phosphatase auxilin, PHOSPHATE ION, ...
Authors:Jiang, J., Maes, E.G., Wang, L., Taylor, A.B., Hinck, A.P., Lafer, E.M., Sousa, R.
Deposit date:2007-08-10
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
2QWQ
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CRYSTAL STRUCTURE OF DISULFIDE-BOND-CROSSLINKED COMPLEX OF BOVINE HSC70 (1-394AA)R171C AND BOVINE AUXILIN (810-910AA)D876C IN THE AMPPNP HYDROLYZED FORM
Descriptor:Heat shock cognate 71 kDa protein, Putative tyrosine-protein phosphatase auxilin, PHOSPHATE ION, ...
Authors:Jiang, J., Maes, E.G., Wang, L., Taylor, A.B., Hinck, A.P., Lafer, E.M., Sousa, R.
Deposit date:2007-08-10
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
2QWR
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CRYSTAL STRUCTURE OF DISULFIDE-BOND-CROSSLINKED COMPLEX OF BOVINE HSC70 (1-394AA)R171C AND BOVINE AUXILIN (810-910AA)D876C IN THE AMPPNP INTACT FORM
Descriptor:Heat shock cognate 71 kDa protein, Putative tyrosine-protein phosphatase auxilin, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Jiang, J., Maes, E.G., Wang, L., Taylor, A.B., Hinck, A.P., Lafer, E.M., Sousa, R.
Deposit date:2007-08-10
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural basis of J cochaperone binding and regulation of Hsp70.
Mol.Cell, 28, 2007
3C7N
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STRUCTURE OF THE HSP110:HSC70 NUCLEOTIDE EXCHANGE COMPLEX
Descriptor:Heat shock protein homolog SSE1, Heat shock cognate, MAGNESIUM ION, ...
Authors:Schuermann, J.P., Jiang, J., Hart, P.J., Sousa, R.
Deposit date:2008-02-07
Release date:2008-05-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.115 Å)
Cite:Structure of the Hsp110:Hsc70 nucleotide exchange machine
Mol.Cell, 31, 2008
4A6V
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X-RAY STRUCTURES OF OXAZOLE HYDROXAMATE ECMETAP-MN COMPLEXES
Descriptor:METHIONINE AMINOPEPTIDASE, MANGANESE (II) ION, CARBONATE ION, ...
Authors:Huguet, F., Melet, A., AlvesdeSousa, R., Lieutaud, A., Chevalier, J., Deschamps, P., Tomas, A., Leulliot, N., Pages, J.M., Artaud, I.
Deposit date:2011-11-09
Release date:2012-06-13
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.
Chemmedchem, 7, 2012
4A6W
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X-RAY STRUCTURES OF OXAZOLE HYDROXAMATE ECMETAP-MN COMPLEXES
Descriptor:METHIONINE AMINOPEPTIDASE, MANGANESE (II) ION, 5-(2-chlorophenyl)-N-hydroxy-1,3-oxazole-2-carboxamide
Authors:Huguet, F., Melet, A., AlvesdeSousa, R., Lieutaud, A., Chevalier, J., Deschamps, P., Tomas, A., Leulliot, N., Pages, J.M., Artaud, I.
Deposit date:2011-11-09
Release date:2012-06-13
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.
Chemmedchem, 7, 2012
4XNR
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VIBRIO VULNIFICUS ADENINE RIBOSWITCH APTAMER DOMAIN, SYNTHESIZED BY POSITION-SELECTIVE LABELING OF RNA (PLOR), IN COMPLEX WITH ADENINE
Descriptor:Vibrio Vulnificus Adenine Riboswitch, ADENINE, MAGNESIUM ION
Authors:Zhang, J., Liu, Y., Wang, Y.-X., Ferre-D'Amare, A.R.
Deposit date:2015-01-16
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Synthesis and applications of RNAs with position-selective labelling and mosaic composition.
Nature, 522, 2015
5JEX
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE, CRYSTALLIZED IN IMIDAZOLE BUFFER
Descriptor:Peptide deformylase, IMIDAZOLE, ZINC ION
Authors:Fieulaine, S., Giglione, C., Meinnel, T.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JEY
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE, CRYSTALLIZED IN CACODYLATE BUFFER
Descriptor:Peptide deformylase, NICKEL (II) ION
Authors:Fieulaine, S., Giglione, C., Meinnel, T.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JEZ
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE IN COMPLEX WITH TRIPEPTIDE MET-ALA-SER
Descriptor:Peptide deformylase, Met-Ala-Ser, ACETATE ION, ...
Authors:Fieulaine, S., Giglione, C., Meinnel, T.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JF0
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE IN COMPLEX WITH TRIPEPTIDE MET-ALA-ARG
Descriptor:Peptide deformylase, MET-ALA-ARG, ACETATE ION, ...
Authors:Fieulaine, S., Giglione, C., Meinnel, T.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JF1
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE IN COMPLEX WITH ACTINONIN
Descriptor:Peptide deformylase, ACTINONIN, ACETATE ION, ...
Authors:Fieulaine, S., Giglione, C., Meinnel, T.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JF2
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE IN COMPLEX WITH INHIBITOR AT002
Descriptor:Peptide deformylase, (3R)-3-{3-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-N-hydroxyheptanamide, ACETATE ION, ...
Authors:Fieulaine, S., Giglione, C., Meinnel, T., Hamiche, K.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JF3
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE IN COMPLEX WITH INHIBITOR AT018
Descriptor:Peptide deformylase, methyl 4-({5-[(3R)-1-(hydroxyamino)-1-oxoheptan-3-yl]-1,2,4-oxadiazol-3-yl}methyl)benzoate, ACETATE ION, ...
Authors:Fieulaine, S., Giglione, C., Meinnel, T.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JF4
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE IN COMPLEX WITH INHIBITOR AT019
Descriptor:Peptide deformylase, (3R)-3-{3-[(1-benzofuran-3-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, ...
Authors:Fieulaine, S., Giglione, C., Meinnel, T.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JF5
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE IN COMPLEX WITH INHIBITOR AT020
Descriptor:Peptide deformylase, (3R)-3-{3-[(2H-1,3-benzodioxol-5-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, ...
Authors:Fieulaine, S., Giglione, C., Meinnel, T.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
5JF6
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CRYSTAL STRUCTURE OF TYPE 2 PDF FROM STREPTOCOCCUS AGALACTIAE IN COMPLEX WITH INHIBITOR 6B (AB47)
Descriptor:Peptide deformylase, 2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide, ACETATE ION, ...
Authors:Fieulaine, S., Giglione, C., Meinnel, T., Hamiche, K.
Deposit date:2016-04-19
Release date:2016-11-30
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A unique peptide deformylase platform to rationally design and challenge novel active compounds.
Sci Rep, 6, 2016
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