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1BXL
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BU of 1bxl by Molmil
STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: BAK PEPTIDE, BCL-XL
Authors:Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W.
Deposit date:1996-10-16
Release date:1997-10-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
2MJN
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BU of 2mjn by Molmil
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
Descriptor: Nucleolysin TIA-1 isoform p40
Authors:Sattler, M, Wang, I.
Deposit date:2014-01-13
Release date:2014-04-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
Nucleic Acids Res., 42, 2014
9GAG
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BU of 9gag by Molmil
Human PEX5 TPR domain in complex with PEX14 KIPSWQIPV peptide
Descriptor: Peroxisomal membrane protein PEX14, Peroxisomal targeting signal 1 receptor
Authors:Emmanouilidis, L, Gaussmann, S, Sattler, M.
Deposit date:2024-07-27
Release date:2024-09-11
Method:SOLUTION NMR
Cite:Humain complexn PEX5 TPR domain with PEX14 KIPSWQIPV peptide
To Be Published
5MMC
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BU of 5mmc by Molmil
Trypanosoma brucei Pex14 N-terminal domain
Descriptor: Peroxin 14
Authors:Emmanouilidis, L, Tripsianes, K, Sattler, M.
Deposit date:2016-12-09
Release date:2017-03-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
Science, 355, 2017
1H5P
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BU of 1h5p by Molmil
Solution structure of the human Sp100b SAND domain by heteronuclear NMR.
Descriptor: NUCLEAR AUTOANTIGEN SP100-B
Authors:Bottomley, M.J, Liu, Z, Collard, M.W, Huggenvik, J.I, Gibson, T.J, Sattler, M.
Deposit date:2001-05-24
Release date:2001-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation.
Nat. Struct. Biol., 8, 2001
6F8G
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BU of 6f8g by Molmil
Co-crystal structure of SPOP MATH domain and hamster Pdx1 fragment
Descriptor: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2017-12-13
Release date:2018-11-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
4UQT
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BU of 4uqt by Molmil
RRM-peptide structure in RES complex
Descriptor: PRE-MRNA-SPLICING FACTOR CWC26, U2 SNRNP COMPONENT IST3
Authors:Tripsianes, K, Friberg, A, Barrandon, C, Seraphin, B, Sattler, M.
Deposit date:2014-06-25
Release date:2014-09-03
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A Novel Protein-Protein Interaction in the Res (Retention and Splicing) Complex.
J.Biol.Chem., 289, 2014
1ZZI
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BU of 1zzi by Molmil
Crystal Structure Analysis of the third KH domain of hnRNP K in complex with ssDNA
Descriptor: 5'-D(*CP*TP*CP*CP*CP*C)-3', Heterogeneous nuclear ribonucleoprotein K
Authors:Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S.
Deposit date:2005-06-14
Release date:2005-08-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids
STRUCTURE, 13, 2005
7NDX
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BU of 7ndx by Molmil
Crystal structure of the human HSP40 DNAJB1-CTDs in complex with a peptide of NudC
Descriptor: 1,2-ETHANEDIOL, DnaJ homolog subfamily B member 1, Nuclear migration protein nudC
Authors:Delhommel, F, Zak, K.M, Popowicz, G.M, Sattler, M.
Deposit date:2021-02-02
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.541 Å)
Cite:NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.
Mol.Cell, 82, 2022
2XC7
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BU of 2xc7 by Molmil
Solution Structure of PHAX-RBD in complex with ssRNA
Descriptor: 5'-(AP*UP*CP*GP)-3', PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN
Authors:Mourao, A, Mackereth, C.D, Varrot, A, Cusack, S, Sattler, M.
Deposit date:2010-04-18
Release date:2010-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
2XL1
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BU of 2xl1 by Molmil
Structural basis of translational stalling by human cytomegalovirus (hCMV) and fungal arginine attenuator peptide (AAP)
Descriptor: ARGININE ATTENUATOR PEPTIDE
Authors:Meyer, N.H, Sattler, M.
Deposit date:2010-07-15
Release date:2010-10-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Translational Stalling by Human Cytomegalovirus and Fungal Arginine Attenuator Peptide.
Mol.Cell, 40, 2010
1FHO
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BU of 1fho by Molmil
Solution Structure of the PH Domain from the C. Elegans Muscle Protein UNC-89
Descriptor: UNC-89
Authors:Blomberg, N, Baraldi, E, Sattler, M, Saraste, M, Nilges, M.
Deposit date:2000-08-02
Release date:2000-10-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of a PH domain from the C. elegans muscle protein UNC-89 suggests a novel function.
Structure Fold.Des., 8, 2000
8Q8J
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BU of 8q8j by Molmil
Crystal structure of human GPX4-R152H
Descriptor: Glutathione peroxidase
Authors:Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G.
Deposit date:2023-08-18
Release date:2024-08-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human GPX4-R152H
To Be Published
4EL6
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BU of 4el6 by Molmil
Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs
Descriptor: IL-4-inducing protein
Authors:Mayerhofer, H, Meyer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Sattler, M, Schramm, G, Mueller-Dieckmann, J.
Deposit date:2012-04-10
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure and functional analysis of IPSE/alpha-1, an IL-4-inducing factor secreted from Schistosoma mansoni eggs, reveals an IgE-binding crystallin fold
To be Published
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
Descriptor: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
Authors:Kachariya, N, Sattler, M, Keil, P, Strasser, K.
Deposit date:2022-10-04
Release date:2022-11-09
Last modified:2024-06-19
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
8Q8N
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BU of 8q8n by Molmil
Crystal structure of human GPX4-U46C-I129S-L130S
Descriptor: Phospholipid hydroperoxide glutathione peroxidase
Authors:Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G.
Deposit date:2023-08-18
Release date:2024-08-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration
To Be Published
8POI
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BU of 8poi by Molmil
Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine
Descriptor: 4-pyridin-2-yl-1,3-thiazol-2-amine, Survival of motor neuron-related-splicing factor 30
Authors:Borggraefe, J, Gaussmann, S, Sattler, M.
Deposit date:2023-07-04
Release date:2023-08-23
Last modified:2023-08-30
Method:SOLUTION NMR
Cite:Pharmacological perturbation of the phase-separating protein SMNDC1.
Nat Commun, 14, 2023
3DXB
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BU of 3dxb by Molmil
Structure of the UHM domain of Puf60 fused to thioredoxin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM)
Authors:Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M.
Deposit date:2008-07-24
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60.
J.Biol.Chem., 284, 2009
6DCL
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BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
Authors:Kooshapur, H, Sattler, M.
Deposit date:2018-05-07
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
1T2S
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BU of 1t2s by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2R
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BU of 1t2r by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
Descriptor: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-04-22
Release date:2004-06-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
8P25
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BU of 8p25 by Molmil
Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box
Descriptor: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1
Authors:Hipp, C, Sattler, M.
Deposit date:2023-05-14
Release date:2023-07-26
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
6I7A
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BU of 6i7a by Molmil
Co-crystal structure of human SPOP MATH domain (D140N) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-16
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I41
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BU of 6i41 by Molmil
Co-crystal structure of human SPOP MATH domain (wild-type) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-08
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I5P
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BU of 6i5p by Molmil
Co-crystal structure of human SPOP MATH domain (E47K) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-14
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019

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