Author results

1HCP
  • Download 1hcp
  • View 1hcp
Molmil generated image of 1hcp
DNA RECOGNITION BY THE OESTROGEN RECEPTOR: FROM SOLUTION TO THE CRYSTAL
Descriptor:HUMAN/CHICKEN ESTROGEN RECEPTOR, ZINC ION
Authors:Schwabe, J.W.R., Rhodes, D., Neuhaus, D.
Deposit date:1993-11-23
Release date:1995-11-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:DNA recognition by the oestrogen receptor: from solution to the crystal.
Structure, 1, 1993
1EVV
  • Download 1evv
  • View 1evv
Molmil generated image of 1evv
CRYSTAL STRUCTURE OF YEAST PHENYLALANINE TRANSFER RNA AT 2.0 A RESOLUTION
Descriptor:PHENYLALANINE TRANSFER RNA, MAGNESIUM ION, SPERMINE
Authors:Jovine, L., Djordjevic, S., Rhodes, D.
Deposit date:2000-04-20
Release date:2000-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of yeast phenylalanine tRNA at 2.0 A resolution: cleavage by Mg(2+) in 15-year old crystals.
J.Mol.Biol., 301, 2000
1NCS
  • Download 1ncs
  • View 1ncs
Molmil generated image of 1ncs
NMR STUDY OF SWI5 ZINC FINGER DOMAIN 1
Descriptor:TRANSCRIPTIONAL FACTOR SWI5, ZINC ION
Authors:Dutnall, R.N., Neuhaus, D., Rhodes, D.
Deposit date:1996-02-26
Release date:1996-06-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the first zinc finger domain of SWI5: a novel structural extension to a common fold.
Structure, 4, 1996
1HCQ
  • Download 1hcq
  • View 1hcq
Molmil generated image of 1hcq
THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
Descriptor:DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (ESTROGEN RECEPTOR), ...
Authors:Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D.
Deposit date:1995-01-04
Release date:1995-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.
Cell(Cambridge,Mass.), 75, 1993
1IGN
  • Download 1ign
  • View 1ign
Molmil generated image of 1ign
DNA-BINDING DOMAIN OF RAP1 IN COMPLEX WITH TELOMERIC DNA SITE
Descriptor:DNA (5'-D(*CP*CP*GP*CP*AP*CP*AP*CP*CP*CP*AP*CP*AP*CP*AP*CP*C P*AP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*GP*TP*GP*TP*GP*TP*GP*GP*GP*TP*GP*TP*G P*CP*G)-3'), PROTEIN (RAP1)
Authors:Koenig, P., Giraldo, R., Chapman, L., Rhodes, D.
Deposit date:1996-02-29
Release date:1997-01-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA.
Cell(Cambridge,Mass.), 85, 1996
2DRP
  • Download 2drp
  • View 2drp
Molmil generated image of 2drp
THE CRYSTAL STRUCTURE OF A TWO ZINC-FINGER PEPTIDE REVEALS AN EXTENSION TO THE RULES FOR ZINC-FINGER/DNA RECOGNITION
Descriptor:DNA (5'-D(*CP*TP*AP*AP*TP*AP*AP*GP*GP*AP*TP*AP*AP*CP*GP*TP*C P*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*CP*GP*TP*TP*AP*TP*CP*CP*TP*TP*AP*T P*TP*A)-3'), PROTEIN (TRAMTRACK DNA-BINDING DOMAIN), ...
Authors:Fairall, L., Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D.
Deposit date:1994-06-06
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition.
Nature, 366, 1993
1H6O
  • Download 1h6o
  • View 1h6o
Molmil generated image of 1h6o
DIMERISATION DOMAIN FROM HUMAN TRF1
Descriptor:TELOMERIC REPEAT BINDING FACTOR 1
Authors:Fairall, L., Chapman, L., Rhodes, D.
Deposit date:2001-06-20
Release date:2001-09-05
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2.
Mol.Cell, 8, 2001
1H6P
  • Download 1h6p
  • View 1h6p
Molmil generated image of 1h6p
DIMERISTION DOMAIN FROM HUMAN TRF2
Descriptor:TELOMERIC REPEAT BINDING FACTOR 2, MAGNESIUM ION
Authors:Chapman, L., Fairall, L., Rhodes, D.
Deposit date:2001-06-20
Release date:2001-09-05
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Trfh Dimerization Domain of the Human Telomere Proteins Trf1 and Trf2
Mol.Cell, 8, 2001
1HYV
  • Download 1hyv
  • View 1hyv
Molmil generated image of 1hyv
HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM
Descriptor:INTEGRASE, SULFATE ION, CHLORIDE ION, ...
Authors:Molteni, V., Greenwald, J., Rhodes, D., Hwang, Y., Kwiatkowski, W., Bushman, F.D., Siegel, J.S., Choe, S.
Deposit date:2001-01-22
Release date:2001-04-04
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain.
Acta Crystallogr.,Sect.D, 57, 2001
1HYZ
  • Download 1hyz
  • View 1hyz
Molmil generated image of 1hyz
HIV INTEGRASE CORE DOMAIN COMPLEXED WITH A DERIVATIVE OF TETRAPHENYL ARSONIUM.
Descriptor:INTEGRASE, SULFATE ION, CHLORIDE ION, ...
Authors:Molteni, V., Greenwald, J., Rhodes, D., Hwang, Y., Kwiatkowski, W., Bushman, F.D., Siegel, J.S., Choe, S.
Deposit date:2001-01-22
Release date:2001-04-04
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain.
Acta Crystallogr.,Sect.D, 57, 2001
1ITY
  • Download 1ity
  • View 1ity
Molmil generated image of 1ity
SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HUMAN TRF1
Descriptor:TRF1
Authors:Nishikawa, T., Okamura, H., Nagadoi, A., Konig, P., Rhodes, D., Nishimura, Y., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-02-15
Release date:2002-03-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a telomeric DNA complex of human TRF1
Structure, 9, 2001
1IV6
  • Download 1iv6
  • View 1iv6
Molmil generated image of 1iv6
SOLUTION STRUCTURE OF THE DNA COMPLEX OF HUMAN TRF1
Descriptor:5'-D(*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3', 5'-D(*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*C)-3', TELOMERIC REPEAT BINDING FACTOR 1
Authors:Nishikawa, T., Okamura, H., Nagadoi, A., Konig, P., Rhodes, D., Nishimura, Y., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-03-14
Release date:2002-04-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a telomeric DNA complex of human TRF1.
Structure, 9, 2001
1W0T
  • Download 1w0t
  • View 1w0t
Molmil generated image of 1w0t
HTRF1 DNA-BINDING DOMAIN IN COMPLEX WITH TELOMERIC DNA.
Descriptor:TELOMERIC REPEAT BINDING FACTOR 1, 5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*GP*TP *TP*AP*GP*GP*GP*TP*TP*AP*G)-3', 5'-D(*TP*CP*TP*AP*AP*CP*CP*CP*TP*AP *AP*CP*CP*CP*TP*AP*AP*CP*A)-3'
Authors:Court, R.I., Chapman, L.M., Fairall, L., Rhodes, D.
Deposit date:2004-06-11
Release date:2004-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures
Embo Rep., 6, 2005
1W0U
  • Download 1w0u
  • View 1w0u
Molmil generated image of 1w0u
HTRF2 DNA-BINDING DOMAIN IN COMPLEX WITH TELOMERIC DNA.
Descriptor:TELOMERIC REPEAT BINDING FACTOR 2, 5'-D(*TP*CP*TP*AP*GP*GP*GP*TP*TP*AP *GP*GP*GP*TP*TP*AP*G)-3', 5'-D(*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP *CP*CP*CP*TP*AP*GP*A)-3'
Authors:Court, R.I., Chapman, L.M., Fairall, L., Rhodes, D.
Deposit date:2004-06-11
Release date:2004-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures
Embo Rep., 6, 2005
4AA6
  • Download 4aa6
  • View 4aa6
Molmil generated image of 4aa6
THE OESTROGEN RECEPTOR RECOGNIZES AN IMPERFECTLY PALINDROMIC RESPONSE ELEMENT THROUGH AN ALTERNATIVE SIDE-CHAIN CONFORMATION
Descriptor:ESTROGEN RECEPTOR, 5'-D(*CP*TP*AP*AP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP *CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP *CP*TP*TP*A)-3', ...
Authors:Schwabe, J.W., Chapman, L., Rhodes, D.
Deposit date:2011-11-30
Release date:2011-12-14
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation.
Structure, 3, 1995
4LD9
  • Download 4ld9
  • View 4ld9
Molmil generated image of 4ld9
CRYSTAL STRUCTURE OF THE N-TERMINALLY ACETYLATED BAH DOMAIN OF SIR3 BOUND TO THE NUCLEOSOME CORE PARTICLE
Descriptor:Histone H3.2, Histone H4, Histone H2A, ...
Authors:Arnaudo, N., Fernandez, I.S., McLaughlin, S.H., Peak-Chew, S.Y., Rhodes, D., Martino, F.
Deposit date:2013-06-24
Release date:2013-08-14
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (3.306 Å)
Cite:The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle.
Nat.Struct.Mol.Biol., 20, 2013
6KE9
  • Download 6ke9
  • View 6ke9
Molmil generated image of 6ke9
THE HUMAN TELOMERIC NUCLEOSOME DISPLAYS DISTINCT STRUCTURAL AND DYNAMIC PROPERTIES
Descriptor:Histone H3.1, Histone H4, Histone H2A type 1-B/E, ...
Authors:Soman, A., Liew, C.W., Teo, H.L., Berezhnoy, N., Korolev, N., Rhodes, D., Nordenskiold, L.
Deposit date:2019-07-04
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal Structure and Solution Properties of the Telomeric Nucleosome
Biorxiv, 2019
6L9H
  • Download 6l9h
  • View 6l9h
Molmil generated image of 6l9h
THE HUMAN TELOMERIC NUCLEOSOME DISPLAYS DISTINCT STRUCTURAL AND DYNAMIC PROPERTIES
Descriptor:Histone H3.1, Histone H4, Histone H2A type 1-B/E, ...
Authors:Soman, A., Liew, C.W., Teo, H.L., Berezhnoy, N., Korolev, N., Rhodes, D., Nordenskiold, L.
Deposit date:2019-11-10
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure and Solution Properties of the Telomeric Nucleosome
Biorxiv, 2019
6LDM
  • Download 6ldm
  • View 6ldm
Molmil generated image of 6ldm
STRUCTURAL BASIS OF G-QUADRUPLEX DNA RECOGNITION BY THE YEAST TELOMERIC PROTEIN RAP1
Descriptor:DNA-binding protein RAP1, G-guadruplex DNA, GLYCEROL, ...
Authors:Traczyk, A., Gill, D.J., Chong, W.L., Rhodes, D.
Deposit date:2019-11-22
Release date:2020-03-18
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1.
Nucleic Acids Res., 48, 2020
6LE9
  • Download 6le9
  • View 6le9
Molmil generated image of 6le9
THE HUMAN TELOMERIC NUCLEOSOME DISPLAYS DISTINCT STRUCTURAL AND DYNAMIC PROPERTIES
Descriptor:Histone H3.1, Histone H4, Histone H2A type 1-B/E, ...
Authors:Soman, A., Liew, C.W., Teo, H.L., Berezhnoy, N., Korolev, N., Rhodes, D., Nordenskiold, L.
Deposit date:2019-11-24
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure and Solution Properties of the Telomeric Nucleosome
Biorxiv, 2019
1ZFD
  • Download 1zfd
  • View 1zfd
Molmil generated image of 1zfd
SWI5 ZINC FINGER DOMAIN 2, NMR, 45 STRUCTURES
Descriptor:SWI5, ZINC ION
Authors:Neuhaus, D., Nakaseko, Y., Schwabe, J.W.R., Rhodes, D., Klug, A.
Deposit date:1996-04-04
Release date:1996-10-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy. A zinc-finger structure with a third strand of beta-sheet.
J.Mol.Biol., 228, 1992
3NF6
  • Download 3nf6
  • View 3nf6
Molmil generated image of 3nf6
STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN
Descriptor:Integrase, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Peat, T.S., Newman, J., Deadman, J.J., Rhodes, D.
Deposit date:2010-06-09
Release date:2011-04-27
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design
ANTIVIR.CHEM.CHEMOTHER., 21, 2011
3NF7
  • Download 3nf7
  • View 3nf7
Molmil generated image of 3nf7
STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN
Descriptor:Integrase, SULFATE ION, ACETIC ACID, ...
Authors:Peat, T.S., Newman, J., Deadman, J.J., Rhodes, D.
Deposit date:2010-06-09
Release date:2011-04-27
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design
ANTIVIR.CHEM.CHEMOTHER., 21, 2011
3NF8
  • Download 3nf8
  • View 3nf8
Molmil generated image of 3nf8
STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN
Descriptor:Integrase, SULFATE ION, 6-[(5-chloro-2-oxo-2,3-dihydro-1H-indol-1-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid, ...
Authors:Peat, T.S., Newman, J., Deadman, J.J., Rhodes, D.
Deposit date:2010-06-09
Release date:2011-04-27
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design
ANTIVIR.CHEM.CHEMOTHER., 21, 2011
3NF9
  • Download 3nf9
  • View 3nf9
Molmil generated image of 3nf9
STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN
Descriptor:Integrase, SULFATE ION, 5-[(6-chloro-2-oxo-2,3-dihydro-1H-indol-1-yl)methyl]-1,3-benzodioxole-4-carboxylic acid, ...
Authors:Peat, T.S., Newman, J., Deadman, J.J., Rhodes, D.
Deposit date:2010-06-10
Release date:2011-04-27
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design
ANTIVIR.CHEM.CHEMOTHER., 21, 2011
<12>