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6LYG
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BU of 6lyg by Molmil
Cryo-EM structure of the calcium homeostasis modulator 1 channel
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1
Authors:Ren, Y, Yang, X, Shen, Y.
Deposit date:2020-02-14
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the calcium homeostasis modulator 1 channel.
Sci Adv, 6, 2020
7DSC
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BU of 7dsc by Molmil
CALHM1 open state with disordered CTH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1
Authors:Ren, Y, Yang, X, Shen, Y.Q.
Deposit date:2020-12-30
Release date:2022-01-05
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel.
J.Biol.Chem., 298, 2022
7DSD
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BU of 7dsd by Molmil
CALHM1 close state with disordered CTH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1
Authors:Ren, Y, Yang, X, Shen, Y.Q.
Deposit date:2020-12-30
Release date:2022-01-05
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel.
J.Biol.Chem., 298, 2022
7DSE
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BU of 7dse by Molmil
CALHM1 close state with ordered CTH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1
Authors:Ren, Y, Yang, X, Shen, Y.Q.
Deposit date:2020-12-30
Release date:2022-01-05
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel.
J.Biol.Chem., 298, 2022
3K8P
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BU of 3k8p by Molmil
Structural basis for vesicle tethering by the Dsl1 complex
Descriptor: Dsl1, Protein transport protein SEC39
Authors:Ren, Y, Jeffrey, P.D, Hughson, F.M.
Deposit date:2009-10-14
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1.
Cell(Cambridge,Mass.), 139, 2009
5SUQ
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BU of 5suq by Molmil
Crystal structure of the THO-Sub2 complex
Descriptor: 12-TUNGSTOPHOSPHATE, ATP-dependent RNA helicase SUB2, Tex1, ...
Authors:Ren, Y, Blobel, G.
Deposit date:2016-08-03
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6 Å)
Cite:Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
Elife, 6, 2017
5SUP
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BU of 5sup by Molmil
Crystal structure of the Sub2-Yra1 complex in association with RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase SUB2, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Ren, Y, Schmiege, P, Blobel, G.
Deposit date:2016-08-03
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
Elife, 6, 2017
2JSD
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BU of 2jsd by Molmil
Solution structure of MMP20 complexed with NNGH
Descriptor: CALCIUM ION, Matrix metalloproteinase-20, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, ...
Authors:Arendt, Y, Banci, L, Bertini, I, Cantini, F, Cozzi, R, Del Conte, R, Gonnelli, L, Structural Proteomics in Europe (SPINE)
Deposit date:2007-07-03
Release date:2007-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Catalytic domain of MMP20 (Enamelysin) - the NMR structure of a new matrix metalloproteinase.
Febs Lett., 581, 2007
3MMY
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BU of 3mmy by Molmil
Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nuclear pore complex protein Nup98, mRNA export factor
Authors:Hoelz, A, Ren, Y.
Deposit date:2010-04-20
Release date:2010-06-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1.
Proc.Natl.Acad.Sci.USA, 107, 2010
4OWR
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BU of 4owr by Molmil
Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair Rae1-Nup98
Descriptor: Matrix protein, Nuclear pore complex protein Nup98-Nup96, mRNA export factor
Authors:Ren, Y, Quan, B, Seo, H.S, Blobel, G.
Deposit date:2014-02-03
Release date:2014-06-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 Nup98).
Proc.Natl.Acad.Sci.USA, 111, 2014
3ETU
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BU of 3etu by Molmil
Crystal structure of yeast Dsl1p
Descriptor: Protein transport protein DSL1
Authors:Ren, Y, Jeffrey, P.D, Hughson, F.M.
Deposit date:2008-10-08
Release date:2009-01-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.
Nat.Struct.Mol.Biol., 16, 2009
3ETV
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BU of 3etv by Molmil
Crystal structure of a Tip20p-Dsl1p fusion protein
Descriptor: Protein transport protein TIP20, Protein transport protein DSL1 chimera
Authors:Ren, Y, Jeffrey, P.D, Hughson, F.M.
Deposit date:2008-10-08
Release date:2009-01-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.
Nat.Struct.Mol.Biol., 16, 2009
6ISU
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BU of 6isu by Molmil
Crystal structure of Lys27-linked di-ubiquitin in complex with its selective interacting protein UCHL3
Descriptor: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L3
Authors:Ding, S, Pan, M, Zheng, Q, Ren, Y, Hong, D.
Deposit date:2018-11-19
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.866 Å)
Cite:Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains.
Angew. Chem. Int. Ed. Engl., 58, 2019
6X25
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BU of 6x25 by Molmil
CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 1-PHOSPHATASE INPP1 IN COMPLEX GADOLINIUM AFTER ADDITION OF INOSITOL 1,3,4-TRISPHOSPHATE AND LITHIUM AT 3.2 ANGSTROM RESOLUTION
Descriptor: GADOLINIUM ATOM, Inositol polyphosphate 1-phosphatase, SULFATE ION
Authors:Dollins, D.E, Endo-Streeter, S, Ren, Y, York, J.D.
Deposit date:2020-05-20
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A structural basis for lithium and substrate binding of an inositide phosphatase.
J.Biol.Chem., 296, 2020
8ENK
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BU of 8enk by Molmil
Crystal structure of UAP56 in complex with Tho1, the yeast homolog of human SARNP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Xie, Y, Ren, Y.
Deposit date:2022-09-30
Release date:2023-08-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly.
Cell Rep, 42, 2023
6E5U
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BU of 6e5u by Molmil
Crystal structure of the mRNA export receptor NXF1/NXT1 in complex with influenza virus NS1 protein
Descriptor: NTF2-related export protein 1, Non-structural protein 1, Nuclear RNA export factor 1
Authors:Xie, Y, Ren, Y.
Deposit date:2018-07-23
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis for influenza virus NS1 protein block of mRNA nuclear export.
Nat Microbiol, 4, 2019
7YVA
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BU of 7yva by Molmil
Crystal structure of Candida albicans Fructose-1,6-bisphosphate aldolase complexed with lipoic acid
Descriptor: 1,2-ETHANEDIOL, Candida albicans Fructose-1,6-bisphosphate aldolase, LIPOIC ACID, ...
Authors:Cao, H, Huang, Y, Ren, Y, Wan, J.
Deposit date:2022-08-19
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Crystal structure of Candida albicans Fructose-1,6-bisphosphate aldolase complexed with lipoic acid
To Be Published
4TMP
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BU of 4tmp by Molmil
Crystal structure of AF9 YEATS bound to H3K9ac peptide
Descriptor: 1,2-ETHANEDIOL, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, Protein AF-9
Authors:Li, H, Li, Y, Wang, H, Ren, Y.
Deposit date:2014-06-02
Release date:2014-11-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.
Cell, 159, 2014
6LNK
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BU of 6lnk by Molmil
Candida albicans Fructose-1,6-bisphosphate aldolase
Descriptor: 1,2-ETHANEDIOL, Fructose-bisphosphate aldolase, ZINC ION
Authors:Huang, Y, Cao, H, Ren, Y, Wan, J.
Deposit date:2019-12-30
Release date:2020-12-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.639 Å)
Cite:Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis.
J.Med.Chem., 65, 2022
8WAY
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BU of 8way by Molmil
De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAW
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BU of 8waw by Molmil
De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAT
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BU of 8wat by Molmil
De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAK
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BU of 8wak by Molmil
Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (5.47 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WB0
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BU of 8wb0 by Molmil
De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS
Descriptor: Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAR
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BU of 8war by Molmil
Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II positioned 8nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023

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