3KQR
| The structure of serum amyloid p component bound to phosphoethanolamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ... | Authors: | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | Deposit date: | 2009-11-17 | Release date: | 2010-12-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J.Mol.Recognit., 24, 2011
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1SAC
| THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT | Descriptor: | ACETIC ACID, CALCIUM ION, SERUM AMYLOID P COMPONENT | Authors: | White, H.E, Emsley, J, O'Hara, B.P, Oliva, G, Srinivasan, N, Tickle, I.J, Blundell, T.L, Pepys, M.B, Wood, S.P. | Deposit date: | 1994-01-27 | Release date: | 1994-05-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of pentameric human serum amyloid P component. Nature, 367, 1994
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1GYK
| Serum Amyloid P Component co-crystallised with MOBDG at neutral pH | Descriptor: | CALCIUM ION, METHYL 4,6-O-[(1R)-1-CARBOXYETHYLIDENE]-BETA-D-GALACTOPYRANOSIDE, SERUM AMYLOID P-COMPONENT | Authors: | Thompson, D, Pepys, M.B, Tickle, I, Wood, S.P. | Deposit date: | 2002-04-25 | Release date: | 2003-05-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structures of Crystalline Complexes of Human Serum Amyloid P Component with its Carbohydrate Ligand, the Cyclic Pyruvate Acetal of Galactose J.Mol.Biol., 320, 2002
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1LGN
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2W08
| The structure of serum amyloid P component bound to 0-phospho- threonine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHOTHREONINE, ... | Authors: | Kolstoe, S.E, Pepys, M.B, Wood, S.P. | Deposit date: | 2008-08-12 | Release date: | 2009-04-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular Dissection of Alzheimer'S Disease Neuropathology by Depletion of Serum Amyloid P Component. Proc.Natl.Acad.Sci.USA, 106, 2009
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4FXL
| Crystal structure of the D76N Beta-2 Microglobulin mutant | Descriptor: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M. | Deposit date: | 2012-07-03 | Release date: | 2012-08-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin. N.Engl.J.Med., 366, 2012
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3L2Y
| The structure of C-reactive protein bound to phosphoethanolamine | Descriptor: | C-reactive protein, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER | Authors: | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | Deposit date: | 2009-12-15 | Release date: | 2010-12-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J.Mol.Recognit., 24, 2011
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1B09
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1GNH
| HUMAN C-REACTIVE PROTEIN | Descriptor: | C-REACTIVE PROTEIN, CALCIUM ION | Authors: | Shrive, A.K, Cheetham, G.M.T, Holden, D, Myles, D.A, Turnell, W.G, Volanakis, J.E, Pepys, M.B, Bloomer, A.C, Greenhough, T.J. | Deposit date: | 1996-03-01 | Release date: | 1997-01-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Three dimensional structure of human C-reactive protein. Nat.Struct.Biol., 3, 1996
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3IPB
| Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (11 carbon linker). | Descriptor: | 2,2'-{undecane-1,11-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid, Transthyretin | Authors: | Kolstoe, S.E, Wood, S.P, Pepys, M.B. | Deposit date: | 2009-08-17 | Release date: | 2010-11-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3IPE
| Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (7 carbon linker). | Descriptor: | 2,2'-{heptane-1,7-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid, Transthyretin | Authors: | Kolstoe, S.E, Wood, S.P, Pepys, M.B. | Deposit date: | 2009-08-17 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proc.Natl.Acad.Sci.USA, 107, 2010
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1LYY
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2BX5
| Is FR1 the antibody's Achillies heel | Descriptor: | VD9 VKI LIGHT-CHAIN | Authors: | James, L.C. | Deposit date: | 2005-07-22 | Release date: | 2006-11-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Beta-Edge Interactions in a Pentadecameric Human Antibody Vkappa Domain. J.Mol.Biol., 367, 2007
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3M1O
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1QTJ
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1LOZ
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4MRB
| Wild Type Human Transthyretin pH 7.5 | Descriptor: | CALCIUM ION, Transthyretin | Authors: | Chen, W.J, Wood, S.P. | Deposit date: | 2013-09-17 | Release date: | 2014-01-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proc.Natl.Acad.Sci.USA, 111, 2014
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4MRC
| Human Transthyretin Ser52Pro Mutant | Descriptor: | CALCIUM ION, Transthyretin | Authors: | Chen, W.J, Wood, S.P. | Deposit date: | 2013-09-17 | Release date: | 2014-01-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proc.Natl.Acad.Sci.USA, 111, 2014
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4AVV
| Structure of CPHPC bound to Serum Amyloid P Component | Descriptor: | (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxidanylidene-hexanoyl]pyrrolidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kolstoe, S.E, Jenvey, M.C, Wood, S.P. | Deposit date: | 2012-05-29 | Release date: | 2013-06-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc) Acta Crystallogr.,Sect.D, 70, 2014
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4AVS
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4AVT
| Structure of CPHPC bound to Serum Amyloid P Component | Descriptor: | (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxidanylidene-hexanoyl]pyrrolidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Kolstoe, S.E, Purvis, A, Wood, S.P. | Deposit date: | 2012-05-29 | Release date: | 2013-06-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc) Acta Crystallogr.,Sect.D, 70, 2014
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4AYU
| Structure of N-Acetyl-D-Proline bound to serum amyloid P component | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | Authors: | Hughes, P, Kolstoe, S.E, Wood, S.P. | Deposit date: | 2012-06-22 | Release date: | 2013-07-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc) Acta Crystallogr.,Sect.D, 70, 2014
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