2W08

The structure of serum amyloid P component bound to 0-phospho- threonine

Summary for 2W08

Entry DOI	10.2210/pdb2w08/pdb
Related	1GYK 1LGN 1SAC 2A3W 2A3X 2A3Y
Descriptor	SERUM AMYLOID P-COMPONENT, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	glycoprotein, polymorphism, metal-binding, tau, lectin, calcium, amyloid, secreted, alzheimers
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	5
Total formula weight	118914.59
Authors	Kolstoe, S.E.,Pepys, M.B.,Wood, S.P. (deposition date: 2008-08-12, release date: 2009-04-14, Last modification date: 2023-12-13)
Primary citation	Kolstoe, S.E.,Ridha, B.H.,Bellotti, V.,Wang, N.,Robinson, C.V.,Crutch, S.J.,Keir, G.,Kukkastenvehmas, R.,Gallimore, J.R.,Hutchinson, W.L.,Hawkins, P.N.,Wood, S.P.,Rossor, M.N.,Pepys, M.B. Molecular Dissection of Alzheimer'S Disease Neuropathology by Depletion of Serum Amyloid P Component. Proc.Natl.Acad.Sci.USA, 106:7619-, 2009 Cited by PubMed: 19372378 DOI: 10.1073/PNAS.0902640106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation