2A3Y

Pentameric crystal structure of human serum amyloid P-component bound to Bis-1,2-{[(Z)-2carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane.

Summary for 2A3Y

• Entry DOI: 10.2210/pdb2a3y/pdb
• Related: 1LGN
• Descriptor: Serum amyloid P-component, CALCIUM ION, BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE, ... (4 entities in total)
• Functional Keywords: metal binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02743
• Total number of polymer chains: 5
• Total formula weight: 118994.90

Authors

Ho, J.G.,Kitov, P.I.,Paszkiewicz, E.,Sadowska, J.,Bundle, D.R.,Ng, K.K. (deposition date: 2005-06-27, release date: 2005-07-26, Last modification date: 2023-08-23)

• Primary citation: Ho, J.G.,Kitov, P.I.,Paszkiewicz, E.,Sadowska, J.,Bundle, D.R.,Ng, K.K.; Ligand-assisted Aggregation of Proteins: DIMERIZATION OF SERUM AMYLOID P COMPONENT BY BIVALENT LIGANDS.; J.Biol.Chem., 280:31999-32008, 2005; PubMed: 16036920; DOI: 10.1074/jbc.M504403200

Experimental method

X-RAY DIFFRACTION (2 Å)