Author results

1ZAA
  • Download 1zaa
  • View 1zaa
Molmil generated image of 1zaa
ZINC FINGER-DNA RECOGNITION: CRYSTAL STRUCTURE OF A ZIF268-DNA COMPLEX AT 2.1 ANGSTROMS
Descriptor:DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*GP*CP*CP*CP*AP*CP*GP*C)-3'), PROTEIN (ZIF268), ...
Authors:Pavletich, N.P., Pabo, C.O.
Deposit date:1992-09-17
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A.
Science, 252, 1991
2GLI
  • Download 2gli
  • View 2gli
Molmil generated image of 2gli
FIVE-FINGER GLI/DNA COMPLEX
Descriptor:DNA (5'-D(*TP*TP*TP*CP*GP*TP*CP*TP*TP*GP*GP*GP*TP*GP*GP*TP*CP*CP*AP*CP*G)-3'), DNA (5'-D(*AP*CP*GP*TP*GP*GP*AP*CP*CP*AP*CP*CP*CP*AP*AP*GP*AP*CP*GP*AP*A)-3'), PROTEIN (FIVE-FINGER GLI), ...
Authors:Pavletich, N.P., Pabo, C.O.
Deposit date:1993-11-09
Release date:1993-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.
Science, 261, 1993
4GNX
  • Download 4gnx
  • View 4gnx
Molmil generated image of 4gnx
STRUCTURE OF U. MAYDIS REPLICATION PROTEIN A BOUND TO SSDNA
Descriptor:Putative uncharacterized protein, DNA (25-MER), ZINC ION
Authors:Pavletich, N.P., Fan, J.
Deposit date:2012-08-17
Release date:2013-02-20
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of
To be Published
1IYJ
  • Download 1iyj
  • View 1iyj
Molmil generated image of 1iyj
STRUCTURE OF A BRCA2-DSS1 COMPLEX
Descriptor:Deleted in split hand/split foot protein 1, breast cancer susceptibility
Authors:Pavletich, N.P., Jeffrey, P.D., Yang, H.J.
Deposit date:2002-08-28
Release date:2002-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
1J8F
  • Download 1j8f
  • View 1j8f
Molmil generated image of 1j8f
HUMAN SIRT2 HISTONE DEACETYLASE
Descriptor:SIRTUIN 2, ISOFORM 1, ZINC ION
Authors:Pavletich, N.P., Finnin, M.S., Donigian, J.R.
Deposit date:2001-05-21
Release date:2001-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the histone deacetylase SIRT2.
Nat.Struct.Biol., 8, 2001
3CMU
  • Download 3cmu
  • View 3cmu
Molmil generated image of 3cmu
MECHANISM OF HOMOLOGOUS RECOMBINATION FROM THE RECA-SSDNA/DSDNA STRUCTURES
Descriptor:DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), Protein recA, MAGNESIUM ION, ...
Authors:Pavletich, N.P.
Deposit date:2008-03-24
Release date:2008-05-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3CMV
  • Download 3cmv
  • View 3cmv
Molmil generated image of 3cmv
MECHANISM OF HOMOLOGOUS RECOMBINATION FROM THE RECA-SSDNA/DSDNA STRUCTURES
Descriptor:Protein recA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Pavletich, N.P.
Deposit date:2008-03-24
Release date:2008-05-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3CMW
  • Download 3cmw
  • View 3cmw
Molmil generated image of 3cmw
MECHANISM OF HOMOLOGOUS RECOMBINATION FROM THE RECA-SSDNA/DSDNA STRUCTURES
Descriptor:DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), Protein recA, MAGNESIUM ION, ...
Authors:Pavletich, N.P.
Deposit date:2008-03-24
Release date:2008-05-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3CMX
  • Download 3cmx
  • View 3cmx
Molmil generated image of 3cmx
MECHANISM OF HOMOLOGOUS RECOMBINATION FROM THE RECA-SSDNA/DSDNA STRUCTURES
Descriptor:DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), DNA (5'-D(*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DA)-3'), Protein recA, ...
Authors:Pavletich, N.P.
Deposit date:2008-03-24
Release date:2008-05-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3I6U
  • Download 3i6u
  • View 3i6u
Molmil generated image of 3i6u
STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE
Descriptor:Serine/threonine-protein kinase Chk2
Authors:Pavletich, N.P.
Deposit date:2009-07-07
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase.
Mol.Cell, 35, 2009
3I6W
  • Download 3i6w
  • View 3i6w
Molmil generated image of 3i6w
STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE
Descriptor:Serine/threonine-protein kinase Chk2
Authors:Pavletich, N.P.
Deposit date:2009-07-07
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase.
Mol.Cell, 35, 2009
3S4W
  • Download 3s4w
  • View 3s4w
Molmil generated image of 3s4w
STRUCTURE OF THE FANCI-FANCD2 COMPLEX
Descriptor:Fanconi anemia group I protein homolog, Fanconi anemia group D2 protein homolog
Authors:Pavletich, N.P.
Deposit date:2011-05-20
Release date:2011-07-27
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (3.408 Å)
Cite:Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.
Science, 333, 2011
3S4Z
  • Download 3s4z
  • View 3s4z
Molmil generated image of 3s4z
STRUCTURE OF A Y DNA-FANCI COMPLEX
Descriptor:dna repair 1
Authors:Pavletich, N.P.
Deposit date:2011-05-20
Release date:2011-07-27
Last modified:2011-10-19
Method:X-RAY DIFFRACTION (7.8 Å)
Cite:Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.
Science, 333, 2011
3S51
  • Download 3s51
  • View 3s51
Molmil generated image of 3s51
STRUCTURE OF FANCI
Descriptor:Fanconi anemia group I protein homolog
Authors:Pavletich, N.P.
Deposit date:2011-05-20
Release date:2011-07-27
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.
Science, 333, 2011
4GOP
  • Download 4gop
  • View 4gop
Molmil generated image of 4gop
STRUCTURE AND CONFORMATIONAL CHANGE OF A REPLICATION PROTEIN A HETEROTRIMER BOUND TO SSDNA
Descriptor:Putative uncharacterized protein, DNA (25-MER), ZINC ION
Authors:Pavletich, N.P., Jie, F.
Deposit date:2012-08-20
Release date:2012-11-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and conformational change of a replication protein A heterotrimer bound to ssDNA.
Genes Dev., 26, 2012
4JSN
  • Download 4jsn
  • View 4jsn
Molmil generated image of 4jsn
STRUCTURE OF MTORDELTAN-MLST8 COMPLEX
Descriptor:Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8
Authors:Pavletich, N.P.
Deposit date:2013-03-22
Release date:2013-05-08
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:mTOR kinase structure, mechanism and regulation.
Nature, 497, 2013
4JSP
  • Download 4jsp
  • View 4jsp
Molmil generated image of 4jsp
STRUCTURE OF MTORDELTAN-MLST8-ATPGAMMAS-MG COMPLEX
Descriptor:Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Pavletich, N.P., Yang, H.
Deposit date:2013-03-22
Release date:2013-05-01
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:mTOR kinase structure, mechanism and regulation.
Nature, 497, 2013
4JSV
  • Download 4jsv
  • View 4jsv
Molmil generated image of 4jsv
MTOR KINASE STRUCTURE, MECHANISM AND REGULATION.
Descriptor:Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Pavletich, N.P., Yang, H.
Deposit date:2013-03-22
Release date:2013-05-01
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:mTOR kinase structure, mechanism and regulation.
Nature, 497, 2013
4JSX
  • Download 4jsx
  • View 4jsx
Molmil generated image of 4jsx
STRUCTURE OF MTORDELTAN-MLST8-TORIN2 COMPLEX
Descriptor:Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one
Authors:Pavletich, N.P., Yang, H.
Deposit date:2013-03-22
Release date:2013-05-08
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:mTOR kinase structure, mechanism and regulation.
Nature, 497, 2013
4JT5
  • Download 4jt5
  • View 4jt5
Molmil generated image of 4jt5
MTORDELTAN-MLST8-PP242 COMPLEX
Descriptor:Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, 2-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol
Authors:Pavletich, N.P., Yang, H.
Deposit date:2013-03-22
Release date:2013-05-08
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:mTOR kinase structure, mechanism and regulation.
Nature, 497, 2013
4JT6
  • Download 4jt6
  • View 4jt6
Molmil generated image of 4jt6
STRUCTURE OF MTORDELTAN-MLST8-PI-103 COMPLEX
Descriptor:mTOR, mLST8, 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL
Authors:Pavletich, N.P., Yang, H.
Deposit date:2013-03-22
Release date:2013-05-08
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:mTOR kinase structure, mechanism and regulation.
Nature, 497, 2013
4RI8
  • Download 4ri8
  • View 4ri8
Molmil generated image of 4ri8
FAN1 NUCLEASE BOUND TO 5' PHOSPHORYLATED P(DG)/3'(DT-DT-DT-DT) DOUBLE FLAP DNA
Descriptor:Fanconi-associated nuclease 1, DNA (5'-D(*TP*TP*TP*GP*AP*GP*GP*AP*GP*TP*CP*TP*TP*T)-3'), DNA (5'-D(P*GP*AP*GP*GP*CP*GP*TP*G)-3'), ...
Authors:Pavletich, N.P., Wang, R.
Deposit date:2014-10-05
Release date:2014-12-03
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
4RI9
  • Download 4ri9
  • View 4ri9
Molmil generated image of 4ri9
FAN1 NUCLEASE BOUND TO 5' PHOSPHORYLATED P(DT)/3'(DT-DT-DT-DT-DT-DT-DT-DT) DOUBLE FLAP DNA
Descriptor:Fanconi-associated nuclease 1, DNA (5'-D(P*TP*AP*GP*CP*CP*AP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*AP*CP*TP*CP*CP*TP*CP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
Authors:Pavletich, N.P., Wang, R.
Deposit date:2014-10-05
Release date:2014-12-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
4RIA
  • Download 4ria
  • View 4ria
Molmil generated image of 4ria
FAN1 NUCLEASE BOUND TO 5' PHOSPHORYLATED NICKED DNA
Descriptor:Fanconi-associated nuclease 1, DNA (5'-D(P*AP*GP*CP*CP*AP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), ...
Authors:Pavletich, N.P., Wang, R.
Deposit date:2014-10-05
Release date:2014-12-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
4RIB
  • Download 4rib
  • View 4rib
Molmil generated image of 4rib
FAN1 NUCLEASE BOUND TO 5' PHOSPHORYLATED P(DT) SINGLE FLAP DNA
Descriptor:Fanconi-associated nuclease 1, DNA (5'-D(P*TP*AP*GP*CP*CP*AP*CP*GP*CP*CP*TP*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*GP*GP*AP*GP*TP*CP*T)-3'), ...
Authors:Pavletich, N.P., Wang, R.
Deposit date:2014-10-05
Release date:2014-12-03
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014