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1DC4
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STRUCTURAL ANALYSIS OF GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE FROM ESCHERICHIA COLI: DIRECT EVIDENCE FOR SUBSTRATE BINDING AND COFACTOR-INDUCED CONFORMATIONAL CHANGES
Descriptor:GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, SN-GLYCEROL-3-PHOSPHATE
Authors:Yun, M., Park, C.-G., Kim, J.-Y., Park, H.-W.
Deposit date:1999-11-04
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of glyceraldehyde 3-phosphate dehydrogenase from Escherichia coli: direct evidence of substrate binding and cofactor-induced conformational changes.
Biochemistry, 39, 2000
1DC5
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STRUCTURAL ANALYSIS OF GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE FROM ESCHERICHIA COLI: DIRECT EVIDENCE FOR SUBSTRATE BINDING AND COFACTOR-INDUCED CONFORMATIONAL CHANGES
Descriptor:GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
Authors:Yun, M., Park, C.-G., Kim, J.-Y., Park, H.-W.
Deposit date:1999-11-04
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of glyceraldehyde 3-phosphate dehydrogenase from Escherichia coli: direct evidence of substrate binding and cofactor-induced conformational changes.
Biochemistry, 39, 2000
1DC6
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STRUCTURAL ANALYSIS OF GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE FROM ESCHERICHIA COLI: DIRECT EVIDENCE FOR SUBSTRATE BINDING AND COFACTOR-INDUCED CONFORMATIONAL CHANGES.
Descriptor:GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Yun, M., Park, C.-G., Kim, J.-Y., Park, H.-W.
Deposit date:1999-11-04
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of glyceraldehyde 3-phosphate dehydrogenase from Escherichia coli: direct evidence of substrate binding and cofactor-induced conformational changes.
Biochemistry, 39, 2000
1M7E
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CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE BINDING DOMAIN(PTB) OF MOUSE DISABLED 2(DAB2):IMPLICATIONS FOR REELING SIGNALING
Descriptor:Disabled homolog 2, NGYENPTYK peptide
Authors:Yun, M., Keshvara, L., Park, C.-G., Zhang, Y.-M., Dickerson, J.B., Zheng, J., Rock, C.O., Curran, T., Park, H.-W.
Deposit date:2002-07-19
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of the Dab homology domains of mouse disabled 1 and 2
J.Biol.Chem., 278, 2003
1N6M
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ROTATION OF THE STALK/NECK AND ONE HEAD IN A NEW CRYSTAL STRUCTURE OF THE KINESIN MOTOR PROTEIN, NCD
Descriptor:Claret segregational protein, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Yun, M., Bronner, C.E., Park, C.-G., Cha, S.-S., Park, H.-W., Endow, S.A.
Deposit date:2002-11-11
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd
EMBO J., 22, 2003
1OQN
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CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE BINDING DOMAIN (PTB) OF MOUSE DISABLED 1 (DAB1)
Descriptor:Disabled homolog 1, Alzheimer's disease amyloid A4 protein homolog, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Authors:Yun, M., Keshvara, L., Park, C.-G., Zhang, Y.-M., Dickerson, J.B., Zheng, J., Rock, C.O., Curran, T., Park, H.-W.
Deposit date:2003-03-10
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the Dab homology domains of mouse disabled 1 and 2
J.Biol.Chem., 278, 2003
1SQ5
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CRYSTAL STRUCTURE OF E. COLI PANTOTHENATE KINASE
Descriptor:Pantothenate kinase, PANTOTHENOIC ACID, ADENOSINE-5'-DIPHOSPHATE
Authors:Ivey, R.A., Zhang, Y.-M., Virga, K.G., Hevener, K., Lee, R.E., Rock, C.O., Jackowski, S., Park, H.-W.
Deposit date:2004-03-17
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites.
J.Biol.Chem., 279, 2004
1DNP
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STRUCTURE OF DEOXYRIBODIPYRIMIDINE PHOTOLYASE
Descriptor:DNA PHOTOLYASE, FLAVIN-ADENINE DINUCLEOTIDE, 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID
Authors:Park, H.-W., Sancar, A., Deisenhofer, J.
Deposit date:1995-07-03
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of DNA photolyase from Escherichia coli.
Science, 268, 1995
1QHT
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DNA POLYMERASE FROM THERMOCOCCUS SP. 9ON-7 ARCHAEON
Descriptor:PROTEIN (DNA POLYMERASE)
Authors:Park, H.-W., Rodriguez, A.C., Beese, L.S.
Deposit date:1999-05-26
Release date:2000-05-26
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7.
J.Mol.Biol., 299, 2000
1F9T
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CRYSTAL STRUCTURES OF KINESIN MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE MOTOR ATPASE
Descriptor:KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Yun, M., Zhang, X., Park, C.-G., Park, H.-W., Endow, S.A.
Deposit date:2000-07-11
Release date:2001-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A structural pathway for activation of the kinesin motor ATPase.
EMBO J., 20, 2001
1FT1
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CRYSTAL STRUCTURE OF PROTEIN FARNESYLTRANSFERASE AT 2.25 ANGSTROMS RESOLUTION
Descriptor:PROTEIN FARNESYLTRANSFERASE, ZINC ION
Authors:Beese, L.S., Park, H.-W.
Deposit date:1997-03-17
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution.
Science, 275, 1997
1JYK
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CATALYTIC MECHANISM OF CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE FROM STREPTOCOCCUS PNEUMONIAE (LICC)
Descriptor:CTP:phosphocholine Cytidylyltransferase
Authors:Kwak, B.-Y., Yun, M., Park, H.-w.
Deposit date:2001-09-12
Release date:2002-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniae.
J.Biol.Chem., 277, 2002
1JYL
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CATALYTIC MECHANISM OF CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE FROM STREPTOCOCCUS PNEUMONIAE (LICC)
Descriptor:CTP:phosphocholine Cytidylyltransferase, MAGNESIUM ION, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM
Authors:Kwak, B.-Y., Yun, M., Park, H.-w.
Deposit date:2001-09-12
Release date:2002-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniae.
J.Biol.Chem., 277, 2002
4DVQ
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STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH DEOXYCORTICOSTERONE
Descriptor:Cytochrome P450 11B2, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Strushkevich, N., Shen, L., Tempel, W., Arrowsmith, C., Edwards, A., Usanov, S.A., Park, H.-W.
Deposit date:2012-02-23
Release date:2013-01-30
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural insights into aldosterone synthase substrate specificity and targeted inhibition.
Mol.Endocrinol., 27, 2013
4FDH
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STRUCTURE OF HUMAN ALDOSTERONE SYNTHASE, CYP11B2, IN COMPLEX WITH FADROZOLE
Descriptor:Cytochrome P450 11B2, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Strushkevich, N., Shen, L., Tempel, W., Arrowsmith, C., Edwards, A., Usanov, S.A., Park, H.-W.
Deposit date:2012-05-28
Release date:2013-01-30
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural insights into aldosterone synthase substrate specificity and targeted inhibition.
Mol.Endocrinol., 27, 2013
4QX0
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CRY3A TOXIN STRUCTURE OBTAINED BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY FROM IN VIVO GROWN CRYSTALS ISOLATED FROM BACILLUS THURINGIENSIS AND DATA PROCESSED WITH THE CCTBX.XFEL SOFTWARE SUITE
Descriptor:Pesticidal crystal protein cry3Aa
Authors:Sawaya, M.R., Cascio, D., Gingery, M., Rodriguez, J., Goldschmidt, L., Colletier, J.-P., Messerschmidt, M., Boutet, S., Koglin, J.E., Williams, G.J., Brewster, A.S., Nass, K., Hattne, J., Botha, S., Doak, R.B., Shoeman, R.L., DePonte, D.P., Park, H.-W., Federici, B.A., Sauter, N.K., Schlichting, I., Eisenberg, D.
Deposit date:2014-07-17
Release date:2014-08-13
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QX1
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CRY3A TOXIN STRUCTURE OBTAINED BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY FROM IN VIVO GROWN CRYSTALS ISOLATED FROM BACILLUS THURINGIENSIS AND DATA PROCESSED WITH THE CRYSTFEL SOFTWARE SUITE
Descriptor:Pesticidal crystal protein cry3Aa
Authors:Sawaya, M.R., Cascio, D., Gingery, M., Rodriguez, J., Goldschmidt, L., Colletier, J.-P., Messerschmidt, M., Boutet, S., Koglin, J.E., Williams, G.J., Brewster, A.S., Nass, K., Hattne, J., Botha, S., Doak, R.B., Shoeman, R.L., DePonte, D.P., Park, H.-W., Federici, B.A., Sauter, N.K., Schlichting, I., Eisenberg, D.
Deposit date:2014-07-17
Release date:2014-08-13
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QX2
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CRY3A TOXIN STRUCTURE OBTAINED BY INJECTING BACILLUS THURINGIENSIS CELLS IN AN XFEL BEAM, COLLECTING DATA BY SERIAL FEMTOSECOND CRYSTALLOGRAPHIC METHODS AND PROCESSING DATA WITH THE CCTBX.XFEL SOFTWARE SUITE
Descriptor:Pesticidal crystal protein cry3Aa
Authors:Sawaya, M.R., Cascio, D., Gingery, M., Rodriguez, J., Goldschmidt, L., Colletier, J.-P., Messerschmidt, M., Boutet, S., Koglin, J.E., Williams, G.J., Brewster, A.S., Nass, K., Hattne, J., Botha, S., Doak, R.B., Shoeman, R.L., DePonte, D.P., Park, H.-W., Federici, B.A., Sauter, N.K., Schlichting, I., Eisenberg, D.
Deposit date:2014-07-17
Release date:2014-08-13
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QX3
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CRY3A TOXIN STRUCTURE OBTAINED BY INJECTING BACILLUS THURINGIENSIS CELLS IN AN XFEL BEAM, COLLECTING DATA BY SERIAL FEMTOSECOND CRYSTALLOGRAPHIC METHODS AND PROCESSING DATA WITH THE CRYSTFEL SOFTWARE SUITE
Descriptor:Pesticidal crystal protein cry3Aa
Authors:Sawaya, M.R., Cascio, D., Gingery, M., Rodriguez, J., Goldschmidt, L., Colletier, J.-P., Messerschmidt, M., Boutet, S., Koglin, J.E., Williams, G.J., Brewster, A.S., Nass, K., Hattne, J., Botha, S., Doak, R.B., Shoeman, R.L., DePonte, D.P., Park, H.-W., Federici, B.A., Sauter, N.K., Schlichting, I., Eisenberg, D.
Deposit date:2014-07-17
Release date:2014-08-13
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
1D8D
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CO-CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A K-RAS4B PEPTIDE SUBSTRATE AND FPP ANALOG AT 2.0A RESOLUTION
Descriptor:farnesyltransferase (alpha subunit), farnesyltransferase (beta subunit), K-RAS4B PEPTIDE SUBSTRATE, ...
Authors:Long, S.B., Casey, P.J., Beese, L.S.
Deposit date:1999-10-22
Release date:2000-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
Structure Fold.Des., 8, 2000
1D8E
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ZINC-DEPLETED FTASE COMPLEXED WITH K-RAS4B PEPTIDE SUBSTRATE AND FPP ANALOG.
Descriptor:FARNESYLTRANSFERASE (ALPHA SUBUNIT), FARNESYLTRANSFERASE (BETA SUBUNIT), K-RAS4B PEPTIDE SUBSTRATE, ...
Authors:Long, S.B., Casey, P.J., Beese, L.S.
Deposit date:1999-10-22
Release date:2000-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
Structure Fold.Des., 8, 2000
1JCQ
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CRYSTAL STRUCTURE OF HUMAN PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750
Descriptor:PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT, BETA SUBUNIT, ...
Authors:Long, S.B., Casey, P.J., Beese, L.S.
Deposit date:2001-06-11
Release date:2001-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JCR
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CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE NON-SUBSTRATE TETRAPEPTIDE INHIBITOR CVFM AND FARNESYL DIPHOSPHATE SUBSTRATE
Descriptor:PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT, BETA SUBUNIT, ...
Authors:Long, S.B., Casey, P.J., Beese, L.S.
Deposit date:2001-06-11
Release date:2001-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JCS
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CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE
Descriptor:PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT, BETA SUBUNIT, ...
Authors:Long, S.B., Casey, P.J., Beese, L.S.
Deposit date:2001-06-11
Release date:2001-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Proc.Natl.Acad.Sci.USA, 98, 2001