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1N3U
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CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE 1 (HO-1) IN COMPLEX WITH ITS SUBSTRATE HEME, CRYSTAL FORM B
Descriptor:heme oxygenase 1, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L., Schuller, D.J., Friedman, J.P., Li, H., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2002-10-29
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1
J.Biol.Chem., 278, 2003
1N45
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X-RAY CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE-1 (HO-1) IN COMPLEX WITH ITS SUBSTRATE HEME
Descriptor:heme oxygenase 1, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schuller, D.J., Wilks, A., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2002-10-30
Release date:2002-11-13
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1.
J. Biol. Chem., 278, 2003
1F4T
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THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS WITH 4-PHENYLIMIDAZOLE BOUND
Descriptor:CYTOCHROME P450 119, ZINC ION, SULFATE ION, ...
Authors:Yano, J.K., Koo, L.S., Schuller, D.J., Li, H., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2000-06-09
Release date:2000-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus.
J.Biol.Chem., 275, 2000
1F4U
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THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS
Descriptor:CYTOCHROME P450 119, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Yano, J.K., Koo, L.S., Schuller, D.J., Li, H., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2000-06-09
Release date:2000-10-23
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus.
J.Biol.Chem., 275, 2000
1GU9
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ALKYLPEROXIDASE AHPD
Descriptor:ALKYLHYDROPEROXIDASE D
Authors:Nunn, C.M., Djordjevic, S., Hillas, P.J., Nishida, C., Ortiz de Montellano, P.R.
Deposit date:2002-01-24
Release date:2002-02-14
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Crystal Structure of Mycobacterium Tuberculosis Alkylhydroperoxidase Ahpd, a Potential Target for Antitubercular Drug Design
J.Biol.Chem., 277, 2002
1LW1
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ALKYLPEROXIDASE AHPD H137F MUTANT
Descriptor:ALKYLHYDROPEROXIDASE D
Authors:Nunn, C.M., Djordjevic, S., Ortiz de Montellano, P.R.
Deposit date:2002-05-30
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Mechanism of Mycobacterium tuberculosis Alkylhydroperoxidase AhpD as Defined by Mutagenesis, Crystallography, and Kinetics
J.Biol.Chem., 278, 2003
1ME5
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ALKYLPEROXIDASE AHPD H132Q MUTANT
Descriptor:ALKYLHYDROPEROXIDASE D
Authors:Nunn, C.M., Djordjevic, S., Ortiz de Montellano, P.R.
Deposit date:2002-08-08
Release date:2002-09-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics.
J.Biol.Chem., 278, 2003
1NI6
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COMPARISIONS OF THE HEME-FREE AND-BOUND CRYSTAL STRUCTURES OF HUMAN HEME OXYGENASE-1
Descriptor:Heme oxygenase 1, CHLORIDE ION, TREHALOSE
Authors:Lad, L., Schuller, D.J., Friedman, J., Li, H., Shimizu, H., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2002-12-21
Release date:2003-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1
J.Biol.Chem., 278, 2003
1OYK
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CRYSTAL STRUCTURES OF THE FERRIC, FERROUS, AND FERROUS-NO FORMS OF THE ASP140ALA MUTANT OF HUMAN HEME OXYGENASE-1: CATALYTIC IMPLICATIONS
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L., Wang, J., Li, H., Friedman, J., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-04-04
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1OYL
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CRYSTAL STRUCTURES OF THE FERRIC, FERROUS, AND FERROUS-NO FORMS OF THE ASP140ALA MUTANT OF HUMAN HEME OXYGENASE-1: CATALYTIC IMPLICATIONS
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L., Wang, J., Li, H., Friedman, J., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-04-05
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1OZE
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CRYSTAL STRUCTURES OF THE FERRIC, FERROUS, AND FERROUS-NO FORMS OF THE ASP140ALA MUTANT OF HUMAN HEME OXYGENASE-1:CATALYTIC IMPLICATIONS
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L., Wang, J., Li, H., Friedman, J., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-04-08
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1OZL
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CRYSTAL STRUCTURES OF THE FERRIC, FERROUS, AND FERROUS-NO FORMS OF THE ASP140ALA MUTANT OF HUMAN HEME OXYGENASE-1: CATALYTIC IMPLICATIONS
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE
Authors:Lad, L., Wang, J., Li, H., Friedman, J., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-04-09
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1OZR
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CRYSTAL STRUCTURES OF THE FERRIC, FERROUS AND FERROUS-NO FORMS OF THE ASP140ALA MUTANT OF HUMAN HEME OXYGENASE-1: CATALYTIC IMPLICATIONS
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L., Wang, J., Li, H., Friedman, J., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-04-09
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1OZW
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CRYSTAL STRUCTURES OF THE FERRIC, FERROUS AND FERROUS-NO FORMS OF THE ASP140ALA MUTANT OF HUMAN HEME OXYGENASE-1: CATALYTIC IMPLICATIONS
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE
Authors:Lad, L., Wang, J., Li, H., Friedman, J., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-04-09
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1PKF
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CRYSTAL STRUCTURE OF EPOTHILONE D-BOUND CYTOCHROME P450EPOK
Descriptor:cytochrome p450EpoK, PROTOPORPHYRIN IX CONTAINING FE, EPOTHILONE D
Authors:Nagano, S., Li, H., Shimizu, H., Nishida, C., Ogura, H., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-06-05
Release date:2003-10-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Epothilone D-bound, Epothilone B-bound, and Substrate-free Forms of Cytochrome P450epoK
J.Biol.Chem., 278, 2003
1Q5D
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EPOTHILONE B-BOUND CYTOCHROME P450EPOK
Descriptor:P450 epoxidase, PROTOPORPHYRIN IX CONTAINING FE, 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE
Authors:Nagano, S., Li, H., Shimizu, H., Nishida, C., Ogura, H., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-08-06
Release date:2003-10-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK
J.Biol.Chem., 278, 2003
1Q5E
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SUBSTRATE-FREE CYTOCHROME P450EPOK
Descriptor:P450 epoxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nagano, S., Li, H., Shimizu, H., Nishida, C., Ogura, H., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2003-08-06
Release date:2003-10-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK
J.Biol.Chem., 278, 2003
1S13
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HUMAN HEME OXYGENASE OXIDATITION OF ALPHA- AND GAMMA-MESO-PHENYLHEMES
Descriptor:Heme oxygenase 1, 2-PHENYLHEME
Authors:Wang, J., Niemevz, F., Lad, L., Buldain, G., Poulos, T.L., Ortiz de Montellano, P.R.
Deposit date:2004-01-05
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Human heme oxygenase oxidation of 5- and 15-phenylhemes.
J.Biol.Chem., 279, 2004
1S8C
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CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE IN A COMPLEX WITH BILIVERDINE
Descriptor:Heme oxygenase 1, BILIVERDINE IX ALPHA
Authors:Lad, L., Friedman, J., Li, H., Bhaskar, B., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2004-02-02
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal Structure of Human Heme Oxygenase-1 in a Complex with Biliverdin
Biochemistry, 43, 2004
1T5P
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HUMAN HEME OXYGENASE OXIDATION OF ALPHA- AND GAMMA-MESO-PHENYLHEMES
Descriptor:Heme oxygenase 1, 12-PHENYLHEME
Authors:Wang, J., Niemevz, F., Lad, L., Buldain, G., Poulos, T.L., Ortiz de Montellano, P.R.
Deposit date:2004-05-05
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Human heme oxygenase oxidation of 5- and 15-phenylhemes.
J.Biol.Chem., 279, 2004
1TWN
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CRYSTAL STRUCTURES OF FERROUS AND FERROUS-NO FORMS OF VERDOHEME IN A COMPLEX WITH HUMAN HEME OXYGENASE-1: CATALYTIC IMPLICATIONS FOR HEME CLEAVAGE
Descriptor:Heme oxygenase 1, IRON-OCTAETHYLPORPHYRIN
Authors:Lad, L., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2004-07-01
Release date:2005-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of ferrous and ferrous-NO forms of verdoheme in a complex with human heme oxygenase-1: catalytic implications for heme cleavage.
J.Inorg.Biochem., 98, 2004
1TWR
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CRYSTAL STRUCTURES OF FERROUS AND FERROUS-NO FORMS OF VERDOHEME IN A COMPLEX WITH HUMAN HEME OXYGENASE-1: CATALYTIC IMPLICATIONS FOR HEME CLEAVAGE
Descriptor:Heme oxygenase 1, IRON-OCTAETHYLPORPHYRIN, NITRIC OXIDE
Authors:Lad, L., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2004-07-01
Release date:2005-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of ferrous and ferrous-NO forms of verdoheme in a complex with human heme oxygenase-1: catalytic implications for heme cleavage.
J.Inorg.Biochem., 98, 2004
1XJZ
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CRYSTAL STRUCTURES OF THE G139A, G139A-NO AND G143H MUTANTS OF HUMAN HEME OXYGENASE-1
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2004-09-26
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal Structures of the G139A, G139A-NO and G143H Mutants of Human Heme Oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity.
J.Biol.Inorg.Chem., 10, 2005
1XK0
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CRYSTAL STRUCTURES OF THE G139A, G139A-NO AND G143H MUTANTS OF HUMAN HEME OXYGENASE-1
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE
Authors:Lad, L., Koshkin, A., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2004-09-26
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structures of the G139A, G139A-NO and G143H mutants of human heme oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity.
J.Biol.Inorg.Chem., 10, 2005
1XK1
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CRYSTAL STRUCTURES OF THE G139A, G139A-NO AND G143H MUTANTS OF HUMAN HEME OXYGENASE-1
Descriptor:Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lad, L., Ortiz de Montellano, P.R., Poulos, T.L.
Deposit date:2004-09-26
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structures of the G139A, G139A-NO and G143H mutants of human heme oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity.
J.Biol.Inorg.Chem., 10, 2005
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