1XK1

Crystal Structures of the G139A, G139A-NO and G143H Mutants of Human Heme Oxygenase-1

Summary for 1XK1

• Entry DOI: 10.2210/pdb1xk1/pdb
• Related: 1XJZ 1XK0 1XK2 1XK3
• Descriptor: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• Functional Keywords: heme, heme degredation, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Microsome: P09601
• Total number of polymer chains: 2
• Total formula weight: 55136.24

Authors

Lad, L.,Ortiz de Montellano, P.R.,Poulos, T.L. (deposition date: 2004-09-26, release date: 2005-12-13, Last modification date: 2023-08-23)

• Primary citation: Lad, L.,Koshkin, A.,Ortiz de Montellano, P.R.,Poulos, T.L.; Crystal structures of the G139A, G139A-NO and G143H mutants of human heme oxygenase-1. A finely tuned hydrogen-bonding network controls oxygenase versus peroxidase activity.; J.Biol.Inorg.Chem., 10:138-146, 2005; PubMed: 15690204; DOI: 10.1007/s00775-004-0620-6

Experimental method

X-RAY DIFFRACTION (2.08 Å)