3CBJ
| Chagasin-Cathepsin B complex | Descriptor: | Cathepsin B, Chagasin, PHOSPHATE ION | Authors: | Redzynia, I, Bujacz, G.D, Abrahamson, M, Ljunggren, A, Jaskolski, M, Mort, J.S. | Deposit date: | 2008-02-22 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. J.Biol.Chem., 283, 2008
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3IV2
| Crystal structure of mature apo-Cathepsin L C25A mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin L1, GLYCEROL, ... | Authors: | Adams-Cioaba, M.A, Krupa, J.C, Mort, J.S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J. | Deposit date: | 2009-08-31 | Release date: | 2010-03-23 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the recognition and cleavage of histone H3 by cathepsin L. Nat Commun, 2, 2011
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3K24
| Crystal structure of mature apo-Cathepsin L C25A mutant in complex with Gln-Leu-Ala peptide | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-6)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin L1, ... | Authors: | Adams-Cioaba, M.A, Krupa, J.C, Mort, J.S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-29 | Release date: | 2010-03-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the recognition and cleavage of histone H3 by cathepsin L. Nat Commun, 2, 2011
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1MIR
| RAT PROCATHEPSIN B | Descriptor: | PROCATHEPSIN B | Authors: | Cygler, M, Sivaraman, J, Grochulski, P, Coulombe, R, Storer, A.C, Mort, J.S. | Deposit date: | 1996-01-12 | Release date: | 1997-01-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion. Structure, 4, 1996
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3CBK
| chagasin-cathepsin B | Descriptor: | Cathepsin B, Chagasin | Authors: | Redzynia, I, Bujacz, G.D, Abrahamson, M, Ljunggren, A, Jaskolski, M, Mort, J.S. | Deposit date: | 2008-02-22 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. J.Biol.Chem., 283, 2008
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1THE
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1CPJ
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1CJL
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1CTE
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1CS8
| CRYSTAL STRUCTURE OF PROCATHEPSIN L | Descriptor: | HUMAN PROCATHEPSIN L | Authors: | Cygler, M, Coulombe, R. | Deposit date: | 1999-08-17 | Release date: | 1999-08-23 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment. EMBO J., 15, 1996
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2NNR
| Crystal structure of chagasin, cysteine protease inhibitor from Trypanosoma cruzi | Descriptor: | CHLORIDE ION, Chagasin, GLYCEROL, ... | Authors: | Redzynia, I, Bujacz, G, Ljunggren, A, Jaskolski, M, Abrahamson, M. | Deposit date: | 2006-10-24 | Release date: | 2007-07-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease J.Mol.Biol., 371, 2007
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2NQD
| Crystal structure of cysteine protease inhibitor, chagasin, in complex with human cathepsin L | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Cathepsin L, ... | Authors: | Redzynia, I, Bujacz, G, Ljunggren, A, Jaskolski, M, Abrahamson, M. | Deposit date: | 2006-10-31 | Release date: | 2007-07-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease J.Mol.Biol., 371, 2007
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6XWM
| Mechanism of substrate release in neurotransmitter:sodium symporters: the structure of LeuT in an inward-facing occluded conformation | Descriptor: | Na(+):neurotransmitter symporter (Snf family), PHENYLALANINE, SODIUM ION | Authors: | Boesen, T, Nissen, P, Gotfryd, K, Loland, C.J, Gether, U. | Deposit date: | 2020-01-24 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. Nat Commun, 11, 2020
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