1CPJ
CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
Summary for 1CPJ
Entry DOI | 10.2210/pdb1cpj/pdb |
Descriptor | CATHEPSIN B (2 entities in total) |
Functional Keywords | thiol protease, hydrolase |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Lysosome: P00787 |
Total number of polymer chains | 2 |
Total formula weight | 56883.12 |
Authors | Huber, C.P.,Jia, Z. (deposition date: 1995-07-17, release date: 1995-12-07, Last modification date: 2021-11-03) |
Primary citation | Jia, Z.,Hasnain, S.,Hirama, T.,Lee, X.,Mort, J.S.,To, R.,Huber, C.P. Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design. J.Biol.Chem., 270:5527-5533, 1995 Cited by PubMed: 7890671DOI: 10.1074/jbc.270.10.5527 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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