1CPJ

CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CATHEPSIN B	polymer	260	28441.6	2	UniProt (P00787) Pfam (PF00112)	Rattus norvegicus (Norway rat)
2	C, D (A, B)	water	water		18.0	190	Chemie (HOH)

Sequence modifications

A, B: -5 - 254 (UniProt: P00787)

PDB	External Database	Details
Ala 115	Ser 194	engineered mutation
Ala 223	Val 302	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56883.1
All*	Total formula weight	56883.1

*Water molecules are not included.