1CPJ
CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | CATHEPSIN B | polymer | 260 | 28441.6 | 2 | UniProt (P00787) Pfam (PF00112) In PDB | Rattus norvegicus (Norway rat) | |
2 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A, B: -5 - 254 (UniProt: P00787)
PDB | External Database | Details |
---|---|---|
Ala 115 | Ser 194 | engineered mutation |
Ala 223 | Val 302 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56883.1 | |
All* | Total formula weight | 56883.1 |