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1MIR
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RAT PROCATHEPSIN B
Descriptor:PROCATHEPSIN B
Authors:Cygler, M., Sivaraman, J., Grochulski, P., Coulombe, R., Storer, A.C., Mort, J.S.
Deposit date:1996-01-12
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion.
Structure, 4, 1996
3CBJ
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CHAGASIN-CATHEPSIN B COMPLEX
Descriptor:Cathepsin B, Chagasin, PHOSPHATE ION
Authors:Redzynia, I., Bujacz, G.D., Abrahamson, M., Ljunggren, A., Jaskolski, M., Mort, J.S.
Deposit date:2008-02-22
Release date:2008-05-27
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B.
J.Biol.Chem., 283, 2008
3CBK
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CHAGASIN-CATHEPSIN B
Descriptor:Cathepsin B, Chagasin
Authors:Redzynia, I., Bujacz, G.D., Abrahamson, M., Ljunggren, A., Jaskolski, M., Mort, J.S.
Deposit date:2008-02-22
Release date:2008-05-27
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B.
J.Biol.Chem., 283, 2008
3IV2
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CRYSTAL STRUCTURE OF MATURE APO-CATHEPSIN L C25A MUTANT
Descriptor:Cathepsin L1, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
Authors:Adams-Cioaba, M.A., Krupa, J.C., Mort, J.S., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J.
Deposit date:2009-08-31
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the recognition and cleavage of histone H3 by cathepsin L.
Nat Commun, 2, 2011
3K24
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CRYSTAL STRUCTURE OF MATURE APO-CATHEPSIN L C25A MUTANT IN COMPLEX WITH GLN-LEU-ALA PEPTIDE
Descriptor:Cathepsin L1, H3 peptide, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Adams-Cioaba, M.A., Krupa, J.C., Mort, J.S., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-29
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the recognition and cleavage of histone H3 by cathepsin L.
Nat Commun, 2, 2011
1CJL
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CRYSTAL STRUCTURE OF A CYSTEINE PROTEASE PROFORM
Descriptor:PROCATHEPSIN L
Authors:Coulombe, R., Grochulski, P., Sivaraman, J., Cygler, M.
Deposit date:1996-07-24
Release date:1997-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
1CPJ
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CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
Descriptor:CATHEPSIN B
Authors:Huber, C.P., Jia, Z.
Deposit date:1995-07-17
Release date:1995-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design.
J.Biol.Chem., 270, 1995
1CTE
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CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
Descriptor:CATHEPSIN B, 2-PYRIDINETHIOL
Authors:Huber, C.P., Jia, Z.
Deposit date:1995-05-03
Release date:1995-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design.
J.Biol.Chem., 270, 1995
1THE
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CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
Descriptor:Cathepsin B, amino{[(4S)-4-{[(benzyloxy)carbonyl]amino}-5-{[(2S)-1-(benzyloxy)-4-chloro-3-oxobutan-2-yl]amino}-5-oxopentyl]amino}methaniminium
Authors:Huber, C.P., Jia, Z.
Deposit date:1995-09-15
Release date:1996-03-10
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design.
J.Biol.Chem., 270, 1995
1CS8
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CRYSTAL STRUCTURE OF PROCATHEPSIN L
Descriptor:HUMAN PROCATHEPSIN L
Authors:Cygler, M., Coulombe, R.
Deposit date:1999-08-17
Release date:1999-08-23
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
2NNR
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CRYSTAL STRUCTURE OF CHAGASIN, CYSTEINE PROTEASE INHIBITOR FROM TRYPANOSOMA CRUZI
Descriptor:Chagasin, SULFATE ION, GLYCEROL, ...
Authors:Redzynia, I., Bujacz, G., Ljunggren, A., Jaskolski, M., Abrahamson, M.
Deposit date:2006-10-24
Release date:2007-07-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease
J.Mol.Biol., 371, 2007
2NQD
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CRYSTAL STRUCTURE OF CYSTEINE PROTEASE INHIBITOR, CHAGASIN, IN COMPLEX WITH HUMAN CATHEPSIN L
Descriptor:Chagasin, Cathepsin L, SODIUM ION, ...
Authors:Redzynia, I., Bujacz, G., Ljunggren, A., Jaskolski, M., Abrahamson, M.
Deposit date:2006-10-31
Release date:2007-07-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease
J.Mol.Biol., 371, 2007