Author results

1DSB
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CRYSTAL STRUCTURE OF THE DSBA PROTEIN REQUIRED FOR DISULPHIDE BOND FORMATION IN VIVO
Descriptor:DSBA
Authors:Martin, J.L., Bardwell, J.C.A., Kuriyan, J.
Deposit date:1993-05-24
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the DsbA protein required for disulphide bond formation in vivo.
Nature, 365, 1993
1B6J
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 1
Descriptor:RETROPEPSIN, CYCLIC PEPTIDE INHIBITOR, SULFATE ION
Authors:Martin, J.L., Begun, J., Schindeler, A., Wickramasinghe, W.A., Alewood, D., Alewood, P.F., Bergman, D.A., Brinkworth, R.I., Abbenante, G., March, D.R., Reid, R.C., Fairlie, D.P.
Deposit date:1999-01-17
Release date:2000-01-07
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1B6K
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 5
Descriptor:RETROPEPSIN, SULFATE ION, N-[3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2]HEPTADECA-1(16),13(17),14- TRIEN-11-YLAMINO)-2-HYDROXY-1-(4-HYDROXY-BENZYL)-PROPYL]-3-METHYL-2- (2-OXO-PYRROLIDIN-1-YL)-BUTYRAMIDE
Authors:Martin, J.L., Begun, J., Schindeler, A., Wickramasinghe, W.A., Alewood, D., Alewood, P.F., Bergman, D.A., Brinkworth, R.I., Abbenante, G., March, D.R., Reid, R.C., Fairlie, D.P.
Deposit date:1999-01-17
Release date:2000-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1B6L
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 4
Descriptor:RETROPEPSIN, SULFATE ION, 1-[2-(8-CARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2]HEPTADECA- 1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL]-PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE
Authors:Martin, J.L., Begun, J., Schindeler, A., Wickramasinghe, W.A., Alewood, D., Alewood, P.F., Bergman, D.A., Brinkworth, R.I., Abbenante, G., March, D.R., Reid, R.C., Fairlie, D.P.
Deposit date:1999-01-17
Release date:2000-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1B6M
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 6
Descriptor:RETROPEPSIN, SULFATE ION, [1-BENZYL-3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YLAMINO)-2-HYDROXY-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER
Authors:Martin, J.L., Begun, J., Schindeler, A., Wickramasinghe, W.A., Alewood, D., Alewood, P.F., Bergman, D.A., Brinkworth, R.I., Abbenante, G., March, D.R., Reid, R.C., Fairlie, D.P.
Deposit date:1999-01-17
Release date:2000-01-07
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1B6P
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 7
Descriptor:RETROPEPSIN, SULFATE ION, N-[3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YAMINO)-2-HYDROXY-1-(4-HYDROXY-BENZYL) -PROPYL]-3-METHYL-2-PROPIONYLAMINO-BUTYRAMIDE
Authors:Martin, J.L., Begun, J., Schindeler, A., Wickramasinghe, W.A., Alewood, D., Alewood, P.F., Bergman, D.A., Brinkworth, R.I., Abbenante, G., March, D.R., Reid, R.C., Fairlie, D.P.
Deposit date:1999-01-17
Release date:2000-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
1HNN
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CRYSTAL STRUCTURE OF HUMAN PNMT COMPLEXED WITH SK&F 29661 AND ADOHCY(SAH)
Descriptor:PHENYLETHANOLAMINE N-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, 1,2,3,4-TETRAHYDRO-ISOQUINOLINE-7-SULFONIC ACID AMIDE
Authors:Martin, J.L., Begun, J., McLeish, M.J., Caine, J.M., Grunewald, G.L.
Deposit date:2000-12-07
Release date:2001-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT.
Structure, 9, 2001
1Z1H
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 3
Descriptor:Pol polyprotein, SULFATE ION, N-{(2R)-2-HYDROXY-2-[(8S,11S)-8-ISOPROPYL-6,9-DIOXO-2-OXA-7,10-DIAZABICYCLO[11.2.2]HEPTADECA-1(15),13,16-TRIEN-11-YL]ETHYL}-N-ISOPENTYLBENZENESULFONAMIDE
Authors:Martin, J.L., Begun, J., Schindeler, A., Wickramasinghe, W.A., Alewood, D., Alewood, P.F., Bergman, D.A., Brinkworth, R.I., Abbenante, G., March, D.R., Reid, R.C., Fairlie, D.P.
Deposit date:2005-03-04
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease
Biochemistry, 38, 1999
1Z1R
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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 2
Descriptor:Pol polyprotein, SULFATE ION, 2-[(8S,11S)-11-{(1R)-1-HYDROXY-2-[ISOPENTYL(PHENYLSULFONYL)AMINO]ETHYL}-6,9-DIOXO-2-OXA-7,10-DIAZABICYCLO[11.2.2]HEPTADECA-1(15),13,16-TRIEN-8-YL]ACETAMIDE
Authors:Martin, J.L., Begun, J., Schindeler, A., Wickramasinghe, W.A., Alewood, D., Alewood, P.F., Bergman, D.A., Brinkworth, R.I., Abbenante, G., March, D.R., Reid, R.C., Fairlie, D.P.
Deposit date:2005-03-06
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease
Biochemistry, 38, 1999
2GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, ALPHA-D-GLUCOSE, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
3GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, ALPHA-D-GLUCOSE-1-PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
4GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, 2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE-1-PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
5GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor:GLYCOGEN PHOSPHORYLASE B, GLUCOPYRANOSYL-1-METHYL-PHOSPHONIC ACID, ALPHA-D-GLUCOSE, ...
Authors:Martin, J.L., Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
1A2J
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OXIDIZED DSBA CRYSTAL FORM II
Descriptor:DISULFIDE BOND FORMATION PROTEIN
Authors:Martin, J.L., Guddat, L.W.
Deposit date:1998-01-06
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization.
Structure, 6, 1998
1A2L
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REDUCED DSBA AT 2.7 ANGSTROMS RESOLUTION
Descriptor:DISULFIDE BOND FORMATION PROTEIN
Authors:Martin, J.L., Guddat, L.W.
Deposit date:1998-01-06
Release date:1998-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization.
Structure, 6, 1998
1A2M
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OXIDIZED DSBA AT 2.7 ANGSTROMS RESOLUTION, CRYSTAL FORM III
Descriptor:DISULFIDE BOND FORMATION PROTEIN
Authors:Martin, J.L., Guddat, L.W.
Deposit date:1998-01-06
Release date:1998-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization.
Structure, 6, 1998
1FVJ
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THE 2.06 ANGSTROM STRUCTURE OF THE H32Y MUTANT OF THE DISULFIDE BOND FORMATION PROTEIN (DSBA)
Descriptor:DISULFIDE BOND FORMATION PROTEIN
Authors:Martin, J.L., Guddat, L.W.
Deposit date:1996-08-28
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability.
Protein Sci., 6, 1997
1FVK
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THE 1.7 ANGSTROM STRUCTURE OF WILD TYPE DISULFIDE BOND FORMATION PROTEIN (DSBA)
Descriptor:DISULFIDE BOND FORMATION PROTEIN
Authors:Martin, J.L., Guddat, L.W.
Deposit date:1996-08-28
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability.
Protein Sci., 6, 1997
1CPI
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REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES. DESIGN OF HYDROLYTICALLY STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE
Descriptor:HIV-1 PROTEASE, CYCLIC PEPTIDE INHIBITOR, SULFATE ION
Authors:Martin, J.L.
Deposit date:1995-10-16
Release date:1996-03-08
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES - DESIGN OF HYDROLYTICALLY-STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE.
J.Am.Chem.Soc., 117, 1995
3E90
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WEST NILE VI RUS NS2B-NS3PROTEASE IN COMPLEXED WITH INHIBITOR NAPH-KKR-H
Descriptor:NS2B cofactor, NS3 protease, N~2~-(naphthalen-2-ylcarbonyl)-L-lysyl-N-[(1S)-4-carbamimidamido-1-formylbutyl]-L-lysinamide
Authors:Martin, J.L., Robin, G.
Deposit date:2008-08-21
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation
J.Mol.Biol., 385, 2009
4H8S
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CRYSTAL STRUCTURE OF HUMAN APPL2BARPH DOMAIN
Descriptor:DCC-interacting protein 13-beta
Authors:Martin, J.L., King, G.J.
Deposit date:2012-09-23
Release date:2012-10-17
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Membrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPase.
J.Biol.Chem., 287, 2012
1D4K
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HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR
Descriptor:HIV-1 PROTEASE, SULFATE ION, N-13-[(10S,13S)-9,12-DIOXO-10-(2-BUTYL)-2-OXA-8,11-DIAZABICYCLO [13.2.2] NONADECA-15,17,18-TRIENE] (2R)-BENZYL-(4S)-HYDROXY-5-AMINOPENTANOIC (1R)-HYDROXY-(2S)-INDANEAMIDE
Authors:Tyndall, J.D., Reid, R.C., Tyssen, D.P., Jardine, D.K., Todd, B., Passmore, M., March, D.R., Pattenden, L.K., Alewood, D., Hu, S.H., Alewood, P.F., Birch, C.J., Martin, J.L., Fairlie, D.P.
Deposit date:1999-10-04
Release date:2000-10-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease.
J.Med.Chem., 43, 2000
1D4L
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HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR
Descriptor:HIV-1 PROTEASE, SULFATE ION, (10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENESULFONYL-1''-AMINO-3''-METHYLBUTYL)ETHYL]-8,11-DIOXO-10-ISOPROPYL-2-OXA-9,12-DIAZABICYCLO [13.2.2]NONADECA-15,17,18-TRIENE
Authors:Tyndall, J.D., Reid, R.C., Tyssen, D.P., Jardine, D.K., Todd, B., Passmore, M., March, D.R., Pattenden, L.K., Alewood, D., Hu, S.H., Alewood, P.F., Birch, C.J., Martin, J.L., Fairlie, D.P.
Deposit date:1999-10-04
Release date:2000-10-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease.
J.Med.Chem., 43, 2000
1AC1
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DSBA MUTANT H32L
Descriptor:DSBA
Authors:Guddat, L.W., Martin, J.L.
Deposit date:1997-02-10
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability.
Protein Sci., 6, 1997
1ACV
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DSBA MUTANT H32S
Descriptor:DSBA
Authors:Guddat, L.W., Martin, J.L.
Deposit date:1997-02-10
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability.
Protein Sci., 6, 1997