2F1K
| Crystal structure of Synechocystis arogenate dehydrogenase | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, prephenate dehydrogenase | Authors: | Legrand, P, Dumas, R, Seux, M, Rippert, P, Ravelli, R, Ferrer, J.-L, Matringe, M. | Deposit date: | 2005-11-14 | Release date: | 2006-05-09 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Biochemical Characterization and Crystal Structure of Synechocystis Arogenate Dehydrogenase Provide Insights into Catalytic Reaction Structure, 14, 2006
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5E7F
| Complex between lactococcal phage Tuc2009 RBP head domain and a nanobody (L06) | Descriptor: | Major structural protein 1, nanobody L06 | Authors: | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | Deposit date: | 2015-10-12 | Release date: | 2015-12-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules. Mbio, 7, 2016
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5E7T
| Structure of the tripod (BppUct-A-L) from the baseplate of bacteriophage Tuc2009 | Descriptor: | CALCIUM ION, Major structural protein 1, Minor structural protein 4, ... | Authors: | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | Deposit date: | 2015-10-13 | Release date: | 2015-12-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules. Mbio, 7, 2016
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5E7B
| Structure of a nanobody (vHH) from camel against phage Tuc2009 RBP (BppL, ORF53) | Descriptor: | nanobody nano-L06 | Authors: | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | Deposit date: | 2015-10-12 | Release date: | 2015-12-30 | Last modified: | 2016-05-04 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules. Mbio, 7, 2016
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2UY1
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2V94
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4A6D
| Crystal structure of human N-acetylserotonin methyltransferase (ASMT) in complex with SAM | Descriptor: | GLYCEROL, HYDROXYINDOLE O-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE, ... | Authors: | Legrand, P, Haouz, A, Shepard, W. | Deposit date: | 2011-11-01 | Release date: | 2012-11-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure and Functional Mapping of Human Asmt, the Last Enzyme of the Melatonin Synthesis Pathway. J.Pineal Res., 54, 2013
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4A6E
| Crystal structure of human N-acetylserotonin methyltransferase (ASMT) in complex with SAM and N-acetylserotonin | Descriptor: | GLYCEROL, HYDROXYINDOLE O-METHYLTRANSFERASE, N-ACETYL SEROTONIN, ... | Authors: | Legrand, P, Haouz, A, Shepard, W. | Deposit date: | 2011-11-01 | Release date: | 2012-11-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure and Functional Mapping of Human Asmt, the Last Enzyme of the Melatonin Synthesis Pathway. J.Pineal Res., 54, 2013
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7QXM
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4D5M
| Gonadotropin-releasing hormone agonist | Descriptor: | PHOSPHATE ION, TRIPTORELIN | Authors: | Legrand, P, Le Du, M.-H, Valery, C, Deville-Foillard, S, Paternostre, M, Artzner, F. | Deposit date: | 2014-11-05 | Release date: | 2015-08-12 | Last modified: | 2020-03-11 | Method: | X-RAY DIFFRACTION (0.85 Å) | Cite: | Atomic View of the Histidine Environment Stabilizing Higher- Ph Conformations of Ph-Dependent Proteins. Nat.Commun., 6, 2015
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8AAJ
| Crystal structure of the Pyrococcus abyssi RPA (apo form) | Descriptor: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | Authors: | Legrand, P, Madru, C, Sauguet, L. | Deposit date: | 2022-07-01 | Release date: | 2023-05-03 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | DNA-binding mechanism and evolution of replication protein A. Nat Commun, 14, 2023
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6T66
| Crystal structure of the Vibrio cholerae replicative helicase (DnaB) with GDP-AlF4 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Replicative DNA helicase, ... | Authors: | Legrand, P, Quevillon-Cheruel, S, Li de la Sierra-Gallay, I, Walbott, H. | Deposit date: | 2019-10-17 | Release date: | 2021-04-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Study of the DnaB:DciA interplay reveals insights into the primary mode of loading of the bacterial replicative helicase. Nucleic Acids Res., 49, 2021
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8QQE
| Crystal structure of the complex between DMC1 and the PhePP domain of BRCA2 | Descriptor: | Breast cancer type 2 susceptibility protein, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Miron, S, Legrand, P, Zinn-Justin, S. | Deposit date: | 2023-10-04 | Release date: | 2024-06-19 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (3.461 Å) | Cite: | DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces. Nucleic Acids Res., 52, 2024
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3Q4F
| Crystal structure of xrcc4/xlf-cernunnos complex | Descriptor: | DNA repair protein XRCC4, Non-homologous end-joining factor 1 | Authors: | Ropars, V, Legrand, P, Charbonnier, J.B. | Deposit date: | 2010-12-23 | Release date: | 2011-08-03 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining. Proc.Natl.Acad.Sci.USA, 108, 2011
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2XV4
| Structure of Human RPC62 (partial) | Descriptor: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3, PHOSPHATE ION | Authors: | Lefevre, S, Legrand, P, Fribourg, S. | Deposit date: | 2010-10-22 | Release date: | 2011-03-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure-Function Analysis of Hrpc62 Provides Insights Into RNA Polymerase III Transcription Nat.Struct.Mol.Biol., 18, 2011
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5MKO
| [2Fe-2S] cluster containing TtuA in complex with AMP. | Descriptor: | ADENOSINE MONOPHOSPHATE, FE2/S2 (INORGANIC) CLUSTER, TtuA PH0300, ... | Authors: | Arragain, S, Bimai, O, Legrand, P, Golinelli-Pimpaneau, B. | Deposit date: | 2016-12-05 | Release date: | 2017-06-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MKQ
| TtuA enzyme containing a [4Fe-4S] | Descriptor: | IRON/SULFUR CLUSTER, TtuA PH0300, ZINC ION | Authors: | Arragain, S, Bimai, O, Legrand, P, Golinelli-Pimpaneau, B. | Deposit date: | 2016-12-05 | Release date: | 2017-06-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MKP
| Non redox thiolation in transfer RNAs occuring via sulfur activation by a [4Fe-4S] cluster | Descriptor: | Fe4 H S5, PH0300, ZINC ION | Authors: | Arragain, S, Bimai, O, Legrand, P, Golinelli-Pimpaneau, B. | Deposit date: | 2016-12-05 | Release date: | 2017-06-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7B0H
| TgoT_6G12 Ternary complex | Descriptor: | DNA (5'-D(P*AP*AP*CP*GP*GP*CP*AP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ... | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-19 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B08
| TgoT apo | Descriptor: | DNA polymerase, THYMIDINE-5'-TRIPHOSPHATE, TRIETHYLENE GLYCOL | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.394 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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4V96
| The structure of a 1.8 MDa viral genome injection device suggests alternative infection mechanisms | Descriptor: | BPP, ORF46, ORF48 | Authors: | Veesler, D, Spinelli, S, Mahony, J, Lichiere, J, Blangy, S, Bricogne, G, Legrand, P, Ortiz-Lombardia, M, Campanacci, V, van Sinderen, D, Cambillau, C. | Deposit date: | 2012-02-01 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism. Proc.Natl.Acad.Sci.USA, 109, 2012
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7B07
| TgoT_6G12 apo | Descriptor: | CALCIUM ION, DNA polymerase | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.099 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B0G
| TgoT_6G12 binary with 2 hCTPs | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(P*AP*TP*TP*GP*GP*CP*TP*GP*CP*CP*CP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*GP*GP*GP*CP*AP*GP*()P*())-3'), ... | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-19 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B0F
| TgoT_6G12 Binary complex | Descriptor: | DNA (5'-D(P*AP*AP*CP*GP*GP*CP*TP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ... | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-19 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.797 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B06
| TgoT_RT521 apo | Descriptor: | DNA polymerase | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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