Author results

1FNF
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FRAGMENT OF HUMAN FIBRONECTIN ENCOMPASSING TYPE-III REPEATS 7 THROUGH 10
Descriptor:FIBRONECTIN
Authors:Leahy, D.J., Aukhil, I., Erickson, H.P.
Deposit date:1995-09-30
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region.
Cell(Cambridge,Mass.), 84, 1996
1CD8
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CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION
Descriptor:T CELL CORECEPTOR CD8, SULFATE ION
Authors:Leahy, D.J., Axel, R., Hendrickson, W.A.
Deposit date:1992-01-16
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution.
Cell(Cambridge,Mass.), 68, 1992
1TEN
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STRUCTURE OF A FIBRONECTIN TYPE III DOMAIN FROM TENASCIN PHASED BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
Descriptor:TENASCIN
Authors:Leahy, D.J., Hendrickson, W.A., Aukhil, I., Erickson, H.P.
Deposit date:1992-08-28
Release date:1993-10-31
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein.
Science, 258, 1992
1BAF
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2.9 ANGSTROMS RESOLUTION STRUCTURE OF AN ANTI-DINITROPHENYL-SPIN-LABEL MONOCLONAL ANTIBODY FAB FRAGMENT WITH BOUND HAPTEN
Descriptor:IGG1-KAPPA AN02 FAB (LIGHT CHAIN), IGG1-KAPPA AN02 FAB (HEAVY CHAIN), N-(2-AMINO-ETHYL)-4,6-DINITRO-N'-(2,2,6,6-TETRAMETHYL-1-OXY-PIPERIDIN-4-YL)-BENZENE-1,3-DIAMINE
Authors:Leahy, D.J., Brunger, A.T., Fox, R.O., Hynes, T.R.
Deposit date:1992-01-16
Release date:1994-01-31
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten.
J.Mol.Biol., 221, 1991
1ZON
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CD11A I-DOMAIN WITHOUT BOUND CATION
Descriptor:LEUKOCYTE ADHESION GLYCOPROTEIN
Authors:Leahy, D.J., Qu, A.
Deposit date:1996-06-20
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
1ZOO
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CD11A I-DOMAIN WITH BOUND MAGNESIUM ION
Descriptor:LEUKOCYTE ADHESION GLYCOPROTEIN, MAGNESIUM ION, CHLORIDE ION
Authors:Leahy, D.J., Qu, A.
Deposit date:1996-06-21
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
1ZOP
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CD11A I-DOMAIN WITH BOUND MAGNESIUM ION
Descriptor:I-DOMAIN FRAGMENT OF LFA-1, MANGANESE (II) ION, CHLORIDE ION
Authors:Leahy, D.J., Qu, A.
Deposit date:1996-06-21
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
1LFA
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CD11A I-DOMAIN WITH BOUND MN++
Descriptor:CD11A, MANGANESE (II) ION, CHLORIDE ION
Authors:Leahy, D.J., Qu, A.
Deposit date:1995-09-08
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.
Proc.Natl.Acad.Sci.USA, 92, 1995
1M6B
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STRUCTURE OF THE HER3 (ERBB3) EXTRACELLULAR DOMAIN
Descriptor:Receptor protein-tyrosine kinase erbB-3, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Leahy, D.J., Cho, H.-S.
Deposit date:2002-07-15
Release date:2002-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the extracellular region of HER3 reveals an interdomain tether.
Science, 297, 2002
1S78
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INSIGHTS INTO ERBB SIGNALING FROM THE STRUCTURE OF THE ERBB2-PERTUZUMAB COMPLEX
Descriptor:Receptor protein-tyrosine kinase erbB-2, Pertuzumab Fab light chain, Pertuzumab Fab heavy chain, ...
Authors:Franklin, M.C., Carey, K.D., Vajdos, F.F., Leahy, D.J., de Vos, A.M., Sliwkowski, M.X.
Deposit date:2004-01-29
Release date:2004-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell, 5, 2004
1DDV
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CRYSTAL STRUCTURE OF THE HOMER EVH1 DOMAIN WITH BOUND MGLUR PEPTIDE
Descriptor:GLGF-DOMAIN PROTEIN HOMER, METABOTROPIC GLUTAMATE RECEPTOR MGLUR5
Authors:Beneken, J., Tu, J.C., Xiao, B., Worley, P.F., Leahy, D.J.
Deposit date:1999-11-11
Release date:2000-05-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition.
Neuron, 26, 2000
1DDW
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HOMER EVH1 DOMAIN UNLIGANDED
Descriptor:GLGF-DOMAIN PROTEIN HOMER
Authors:Beneken, J., Tu, J.C., Xiao, B., Worley, P.F., Leahy, D.J.
Deposit date:1999-11-11
Release date:2000-05-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition.
Neuron, 26, 2000
1AT0
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17-KDA FRAGMENT OF HEDGEHOG C-TERMINAL AUTOPROCESSING DOMAIN
Descriptor:17-HEDGEHOG
Authors:Hall, T.M.T., Porter, J.A., Young, K.E., Koonin, E.V., Beachy, P.A., Leahy, D.J.
Deposit date:1997-08-15
Release date:1997-11-12
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.
Cell(Cambridge,Mass.), 91, 1997
1IJX
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF SECRETED FRIZZLED-RELATED PROTEIN 3 (SFRP-3;FZB)
Descriptor:SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3, SULFATE ION
Authors:Dann III, C.E., Hsieh, J.C., Rattner, A., Sharma, D., Nathans, J., Leahy, D.J.
Deposit date:2001-04-30
Release date:2001-07-11
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Nature, 412, 2001
1IJY
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MOUSE FRIZZLED 8 (MFZ8)
Descriptor:FRIZZLED HOMOLOG 8
Authors:Dann III, C.E., Hsieh, J.C., Rattner, A., Sharma, D., Nathans, J., Leahy, D.J.
Deposit date:2001-05-01
Release date:2001-07-11
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Nature, 412, 2001
1N8Y
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF RAT HER2
Descriptor:protooncoprotein, N-ACETYL-D-GLUCOSAMINE
Authors:Cho, H.-S., Mason, K., Ramyar, K.X., Stanley, A.M., Gabelli, S.B., Denney Jr., D.W., Leahy, D.J.
Deposit date:2002-11-21
Release date:2003-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Extracellular Region of HER2 Alone and in complex with the Herceptin Fab
Nature, 421, 2003
1N8Z
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CRYSTAL STRUCTURE OF EXTRACELLULAR DOMAIN OF HUMAN HER2 COMPLEXED WITH HERCEPTIN FAB
Descriptor:Herceptin Fab (antibody) - light chain, Herceptin Fab (antibody) - heavy chain, Receptor protein-tyrosine kinase erbB-2, ...
Authors:Cho, H.-S., Mason, K., Ramyar, K.X., Stanley, A.M., Gabelli, S.B., Denney Jr., D.W., Leahy, D.J.
Deposit date:2002-11-21
Release date:2003-02-18
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structure of the Extracellular Region of HER2 Alone and in Complex with the Herceptin Fab
Nature, 421, 2003
1OT8
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STRUCTURE OF THE ANKYRIN DOMAIN OF THE DROSOPHILA NOTCH RECEPTOR
Descriptor:Neurogenic locus Notch protein, MAGNESIUM ION
Authors:Zweifel, M.E., Leahy, D.J., Hughson, F.M., Barrick, D.
Deposit date:2003-03-21
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and stability of the ankyrin domain of the Drosophila Notch receptor
Protein Sci., 12, 2003
1SZH
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CRYSTAL STRUCTURE OF C. ELEGANS HER-1
Descriptor:Her-1 protein, ACETATE ION
Authors:Hamaoka, B.Y., Dann III, C.E., Geisbrecht, B.V., Leahy, D.J.
Deposit date:2004-04-05
Release date:2004-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A.
Proc.Natl.Acad.Sci.USA, 101, 2004
1VHH
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A POTENTIAL CATALYTIC SITE WITHIN THE AMINO-TERMINAL SIGNALLING DOMAIN OF SONIC HEDGEHOG
Descriptor:SONIC HEDGEHOG, ZINC ION, SULFATE ION
Authors:Hall, T.M.T., Porter, J.A., Beachy, P.A., Leahy, D.J.
Deposit date:1995-10-03
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
Nature, 378, 1995
1YN3
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CRYSTAL STRUCTURES OF EAP DOMAINS FROM STAPHYLOCOCCUS AUREUS REVEAL AN UNEXPECTED HOMOLOGY TO BACTERIAL SUPERANTIGENS
Descriptor:truncated cell surface protein map-w
Authors:Geisbrecht, B.V., Hamaoka, B.Y., Perman, B., Zemla, A., Leahy, D.J.
Deposit date:2005-01-23
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YN4
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CRYSTAL STRUCTURES OF EAP DOMAINS FROM STAPHYLOCOCCUS AUREUS REVEAL AN UNEXPECTED HOMOLOGY TO BACTERIAL SUPERANTIGENS
Descriptor:EapH1, ZINC ION
Authors:Geisbrecht, B.V., Hamaoka, B.Y., Perman, B., Zemla, A., Leahy, D.J.
Deposit date:2005-01-23
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YN5
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CRYSTAL STRUCTURES OF EAP DOMAINS FROM STAPHYLOCOCCUS AUREUS REVEAL AN UNEXPECTED HOMOLOGY TO BACTERIAL SUPERANTIGENS
Descriptor:EapH2
Authors:Geisbrecht, B.V., Hamaoka, B.Y., Perman, B., Zemla, A., Leahy, D.J.
Deposit date:2005-01-23
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
2A90
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CRYSTAL STRUCTURE OF THE TANDEM WWE DOMAIN OF DROSOPHILA DELTEX
Descriptor:Deltex protein
Authors:Zweifel, M.E., Leahy, D.J., Barrick, D.
Deposit date:2005-07-10
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and Notch Receptor Binding of the Tandem WWE Domain of Deltex.
Structure, 13, 2005
2AHX
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CRYSTAL STRUCTURE OF ERBB4/HER4 EXTRACELLULAR DOMAIN
Descriptor:Receptor tyrosine-protein kinase erbB-4, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Bouyain, S., Longo, P.A., Li, S., Ferguson, K.M., Leahy, D.J.
Deposit date:2005-07-28
Release date:2005-09-27
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand
Proc.Natl.Acad.Sci.USA, 102, 2005
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