1AT0

17-kDA fragment of hedgehog C-terminal autoprocessing domain

Summary for 1AT0

Entry DOI	10.2210/pdb1at0/pdb
Descriptor	17-HEDGEHOG (2 entities in total)
Functional Keywords	developmental signaling molecule, cholesterol transfer, signaling protein
Biological source	Drosophila melanogaster (FRUIT FLY)
Cellular location	Nucleus . Protein hedgehog N-product: Cell membrane ; Lipid-anchor . Protein hedgehog C-product: Secreted, extracellular space : Q02936
Total number of polymer chains	1
Total formula weight	15985.78
Authors	Hall, T.M.T.,Porter, J.A.,Young, K.E.,Koonin, E.V.,Beachy, P.A.,Leahy, D.J. (deposition date: 1997-08-15, release date: 1997-11-12, Last modification date: 2017-09-13)
Primary citation	Hall, T.M.,Porter, J.A.,Young, K.E.,Koonin, E.V.,Beachy, P.A.,Leahy, D.J. Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins. Cell(Cambridge,Mass.), 91:85-97, 1997 Cited by PubMed: 9335337 DOI: 10.1016/S0092-8674(01)80011-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation