Author results

3FBV
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CRYSTAL STRUCTURE OF THE OLIGOMER FORMED BY THE KINASE-RIBONUCLEASE DOMAIN OF IRE1
Descriptor:Serine/threonine-protein kinase/endoribonuclease IRE1 (E.C.2.7.11.1, 3.1.26.-)
Authors:Korennykh, A.V., Egea, P.F., Korostelev, A.A., Finer-Moore, J., Zhang, C., Shokat, K.M., Stroud, R.M., Walter, P.
Deposit date:2008-11-19
Release date:2008-12-16
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The unfolded protein response signals through high-order assembly of Ire1.
Nature, 457, 2009
3J6X
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S. CEREVISIAE 80S RIBOSOME BOUND WITH TAURA SYNDROME VIRUS (TSV) IRES, 5 DEGREE ROTATION (CLASS II)
Descriptor:PROTEIN/RNA Complex
Authors:Koh, C.S., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Modification date:2014-12-17
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J6Y
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S. CEREVISIAE 80S RIBOSOME BOUND WITH TAURA SYNDROME VIRUS (TSV) IRES, 2 DEGREE ROTATION (CLASS I)
Descriptor:PROTEIN/RNA Complex
Authors:Koh, C.S., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Modification date:2014-12-17
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J77
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STRUCTURES OF YEAST 80S RIBOSOME-TRNA COMPLEXES IN THE ROTATED AND NON-ROTATED CONFORMATIONS (CLASS II - ROTATED RIBOSOME WITH 1 TRNA)
Descriptor:60S ribosomal protein L1, 60S ribosomal protein L2, 60S ribosomal protein L3, 60S ribosomal protein L4, 60S ribosomal protein L5, 60S ribosomal protein L6, 60S ribosomal protein L7, 60S ribosomal protein L8, 60S ribosomal protein L9, 60S ribosomal protein L10, 60S ribosomal protein L11, 60S ribosomal protein L12, 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15, 60S ribosomal protein L16, 60S ribosomal protein L17, 60S ribosomal protein L18, 60S ribosomal protein L19, 60S ribosomal protein L20, 60S ribosomal protein L21, 60S ribosomal protein L22, 60S ribosomal protein L23, 60S ribosomal protein L24, 60S ribosomal protein L25, 60S ribosomal protein L26, 60S ribosomal protein L27, 60S ribosomal protein L28, 60S ribosomal protein L29, 60S ribosomal protein L30, 60S ribosomal protein L31, 60S ribosomal protein L32, 60S ribosomal protein L33, 60S ribosomal protein L34, 60S ribosomal protein L35, 60S ribosomal protein L36, 60S ribosomal protein L37, 60S ribosomal protein L38, 60S ribosomal protein L39, 60S ribosomal protein L40, 60S ribosomal protein L41, 60S ribosomal protein L42, 60S ribosomal protein L43, 60S acidic ribosomal protein P0, Guanine nucleotide-binding protein subunit beta-like protein, 40S ribosomal protein S0, 40S ribosomal protein S1, 40S ribosomal protein S2, 40S ribosomal protein S3, 40S ribosomal protein S4, 40S ribosomal protein S5, 40S ribosomal protein S6, 40S ribosomal protein S7, 40S ribosomal protein S8, 40S ribosomal protein S9, 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, 40S ribosomal protein S14, 40S ribosomal protein S15, 40S ribosomal protein S16, 40S ribosomal protein S17, 40S ribosomal protein S18, 40S ribosomal protein S19, 40S ribosomal protein S20, 40S ribosomal protein S21, 40S ribosomal protein S22, 40S ribosomal protein S23, 40S ribosomal protein S24, 40S ribosomal protein S25, 40S ribosomal protein S26, 40S ribosomal protein S27, 40S ribosomal protein S28, 40S ribosomal protein S29, 40S ribosomal protein S30, 40S ribosomal protein S31
Authors:Svidritskiy, E., Brilot, A.F., Koh, C.S., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Modification date:2014-12-17
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
3J78
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STRUCTURES OF YEAST 80S RIBOSOME-TRNA COMPLEXES IN THE ROTATED AND NON-ROTATED CONFORMATIONS (CLASS I - NON-ROTATED RIBOSOME WITH 2 TRNAS)
Descriptor:60S ribosomal protein L1, 60S ribosomal protein L2, 60S ribosomal protein L3, 60S ribosomal protein L4, 60S ribosomal protein L5, 60S ribosomal protein L6, 60S ribosomal protein L7, 60S ribosomal protein L8, 60S ribosomal protein L9, 60S ribosomal protein L10, 60S ribosomal protein L11, 60S ribosomal protein L12, 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15, 60S ribosomal protein L16, 60S ribosomal protein L17, 60S ribosomal protein L18, 60S ribosomal protein L19, 60S ribosomal protein L20, 60S ribosomal protein L21, 60S ribosomal protein L22, 60S ribosomal protein L23, 60S ribosomal protein L24, 60S ribosomal protein L25, 60S ribosomal protein L26, 60S ribosomal protein L27, 60S ribosomal protein L28, 60S ribosomal protein L29, 60S ribosomal protein L30, 60S ribosomal protein L31, 60S ribosomal protein L32, 60S ribosomal protein L33, 60S ribosomal protein L34, 60S ribosomal protein L35, 60S ribosomal protein L36, 60S ribosomal protein L37, 60S ribosomal protein L38, 60S ribosomal protein L39, 60S ribosomal protein L40, 60S ribosomal protein L41, 60S ribosomal protein L42, 60S ribosomal protein L43, 60S acidic ribosomal protein P0, Guanine nucleotide-binding protein subunit beta-like protein, 40S ribosomal protein S0, 40S ribosomal protein S1, 40S ribosomal protein S2, 40S ribosomal protein S3, 40S ribosomal protein S4, 40S ribosomal protein S5, 40S ribosomal protein S6, 40S ribosomal protein S7, 40S ribosomal protein S8, 40S ribosomal protein S9, 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, 40S ribosomal protein S14, 40S ribosomal protein S15, 40S ribosomal protein S16, 40S ribosomal protein S17, 40S ribosomal protein S18, 40S ribosomal protein S19, 40S ribosomal protein S20, 40S ribosomal protein S21, 40S ribosomal protein S22, 40S ribosomal protein S23, 40S ribosomal protein S24, 40S ribosomal protein S25, 40S ribosomal protein S26, 40S ribosomal protein S27, 40S ribosomal protein S28, 40S ribosomal protein S29, 40S ribosomal protein S30, 40S ribosomal protein S31
Authors:Svidritskiy, E., Brilot, A.F., Koh, C.S., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Modification date:2014-12-17
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
4V7C
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STRUCTURE OF THE RIBOSOME WITH ELONGATION FACTOR G TRAPPED IN THE PRE-TRANSLOCATION STATE (PRE-TRANSLOCATION 70S*TRNA STRUCTURE)
Descriptor:PROTEIN/RNA Complex
Authors:Brilot, A.F., Korostelev, A.A., Ermolenko, D.N., Grigorieff, N.
Deposit date:2013-11-20
Release date:2014-07-09
Modification date:2014-12-10
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V7D
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STRUCTURE OF THE RIBOSOME WITH ELONGATION FACTOR G TRAPPED IN THE PRE-TRANSLOCATION STATE (PRE-TRANSLOCATION 70S*TRNA*EF-G STRUCTURE)
Descriptor:PROTEIN/RNA Complex
Authors:Brilot, A.F., Korostelev, A.A., Ermolenko, D.N., Grigorieff, N.
Deposit date:2013-11-21
Release date:2014-07-09
Modification date:2014-12-17
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V9N
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CRYSTAL STRUCTURE OF THE 70S RIBOSOME BOUND WITH THE Q253P MUTANT OF RELEASE FACTOR RF2.
Descriptor:Ribosome
Authors:Santos, N., Zhu, J., Donohue, J.P., Korostelev, A.A., Noller, H.F.
Deposit date:2013-04-26
Release date:2014-07-09
Modification date:2014-12-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2.
Structure, 21, 2013
4V9Q
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CRYSTAL STRUCTURE OF BLASTICIDIN S BOUND TO THERMUS THERMOPHILUS 70S RIBOSOME.
Descriptor:PROTEIN/RNA Complex
Authors:Svidritskiy, E., Ling, C., Ermolenko, D.N., Korostelev, A.A.
Deposit date:2013-06-12
Release date:2014-07-09
Modification date:2014-12-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 110, 2013
5D8B
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CRYSTAL STRUCTURE OF T. THERMOPHILUS RIBOSOME CONTAINING A P-SITE WOBBLE MISMATCH
Descriptor:ribosome
Authors:Svidritskiy, E., Korostelev, A.A.
Deposit date:2015-08-17
Release date:2015-10-14
Modification date:2015-11-18
Method:X-RAY DIFFRACTION (3.63 Å)
Cite:Ribosome Structure Reveals Preservation of Active Sites in the Presence of a P-Site Wobble Mismatch.
Structure, 23, 2015
5J4D
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E. COLI RELEASE FACTOR 1 BOUND TO THE 70S RIBOSOME IN RESPONSE TO A PSEUDOURIDYLATED STOP CODON
Descriptor:ribosome
Authors:Svidritskiy, E., Korostelev, A.A.
Deposit date:2016-03-31
Release date:2016-05-18
Modification date:2016-06-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Translation Termination on a Pseudouridylated Stop Codon.
J.Mol.Biol., 428, 2016
5JUO
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE I (FULLY ROTATED 40S SUBUNIT)
Descriptor:uL1 (yeast L1), uL2 (yeast L2), uL3 (yeast L3), uL4 (yeast L4), uL18 (yeast L5), eL6 (yeast L6), uL30 (yeast L7), eL8 (yeast L8), uL6 (yeast L9), uL16 (yeast L10), uL5 (yeast L11), uL11 (yeast L12), eL13 (yeast L13), eL14 (yeast L14), eL15 (yeast L15), uL13 (yeast L16), uL22 (yeast L17), eL18 (yeast L18), eL19 (yeast L19), eL20 (yeast L20), eL21 (yeast L21), eL22 (yeast L22), uL14 (yeast L23), eL24 (yeast L24), uL23 (yeast L25), uL24 (yeast L26), eL27 (yeast L27), uL15 (yeast L28), eL29 (yeast L29), eL30 (yeast L30), eL31 (yeast L31), eL32 (yeast L32), eL33 (yeast L33), eL34 (yeast L34), uL29 (yeast L35), eL36 (yeast L36), eL37 (yeast L37), eL38 (yeast L38), eL39 (yeast L39), eL40 (yeast L40), eL41 (yeast L41), eL42 (yeast L42), eL43 (yeast L43), uL10 (yeast P0), RACK1 (yeast Asc1), uS2 (yeast S0), eS1 (yeast S1), uS5 (yeast S2), uS3 (yeast S3), eS4 (yeast S4), uS7 (yeast S5), eS6 (yeast S6), eS7 (yeast S7), eS8 (yeast S8), uS4 (yeast S9), eS10 (yeast S10), uS17 (yeast S11), eS12 (yeast S12), uS15 (yeast S13), uS11 (yeast S14), uS19 (yeast S15), uS9 (yeast S16), eS17 (yeast S17), uS13 (yeast S18), eS19 (yeast S19), uS10 (yeast S20), eS21 (yeast S21), uS8 (yeast S22), uS12 (yeast S23), eS24 (yeast S24), eS25 (yeast S25), eS26 (yeast S26), eS27 (yeast S27), eS28 (yeast S28), uS14 (yeast S29), eS30 (yeast S30), eS31 (yeast S31), yeast eEF2/RNA Complex
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUP
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE II (MID-ROTATED 40S SUBUNIT)
Descriptor:uL1 (yeast L1), uL2 (yeast L2), uL3 (yeast L3), uL4 (yeast L4), uL18 (yeast L5), eL6 (yeast L6), uL30 (yeast L7), eL8 (yeast L8), uL6 (yeast L9), uL16 (yeast L10), uL5 (yeast L11), uL11 (yeast L12), eL13 (yeast L13), eL14 (yeast L14), eL15 (yeast L15), uL13 (yeast L16), uL22 (yeast L17), eL18 (yeast L18), eL19 (yeast L19), eL20 (yeast L20), eL21 (yeast L21), eL22 (yeast L22), uL14 (yeast L23), eL24 (yeast L24), uL23 (yeast L25), uL24 (yeast L26), eL27 (yeast L27), uL15 (yeast L28), eL29 (yeast L29), eL30 (yeast L30), eL31 (yeast L31), eL32 (yeast L32), eL33 (yeast L33), eL34 (yeast L34), uL29 (yeast L35), eL36 (yeast L36), eL37 (yeast L37), eL38 (yeast L38), eL39 (yeast L39), eL40 (yeast L40), eL41 (yeast L41), eL42 (yeast L42), eL43 (yeast L43), uL10 (yeast P0), RACK1 (yeast Asc1), uS2 (yeast S0), eS1 (yeast S1), uS5 (yeast S2), uS3 (yeast S3), eS4 (yeast S4), uS7 (yeast S5), eS6 (yeast S6), eS7 (yeast S7), eS8 (yeast S8), uS4 (yeast S9), eS10 (yeast S10), uS17 (yeast S11), eS12 (yeast S12), uS15 (yeast S13), uS11 (yeast S14), uS19 (yeast S15), uS9 (yeast S16), eS17 (yeast S17), uS13 (yeast S18), eS19 (yeast S19), uS10 (yeast S20), eS21 (yeast S21), uS8 (yeast S22), uS12 (yeast S23), eS24 (yeast S24), eS25 (yeast S25), eS26 (yeast S26), eS27 (yeast S27), eS28 (yeast S28), uS14 (yeast S29), eS30 (yeast S30), eS31 (yeast S31), yeast eEF2/RNA Complex
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUS
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE III (MID-ROTATED 40S SUBUNIT)
Descriptor:uL1 (yeast L1), uL2 (yeast L2), uL3 (yeast L3), uL4 (yeast L4), uL18 (yeast L5), eL6 (yeast L6), uL30 (yeast L7), eL8 (yeast L8), uL6 (yeast L9), uL16 (yeast L10), uL5 (yeast L11), uL11 (yeast L12), eL13 (yeast L13), eL14 (yeast L14), eL15 (yeast L15), uL13 (yeast L16), uL22 (yeast L17), eL18 (yeast L18), eL19 (yeast L19), eL20 (yeast L20), eL21 (yeast L21), eL22 (yeast L22), uL14 (yeast L23), eL24 (yeast L24), uL23 (yeast L25), uL24 (yeast L26), eL27 (yeast L27), uL15 (yeast L28), eL29 (yeast L29), eL30 (yeast L30), eL31 (yeast L31), eL32 (yeast L32), eL33 (yeast L33), eL34 (yeast L34), uL29 (yeast L35), eL36 (yeast L36), eL37 (yeast L37), eL38 (yeast L38), eL39 (yeast L39), eL40 (yeast L40), eL41 (yeast L41), eL42 (yeast L42), eL43 (yeast L43), uL10 (yeast P0), RACK1 (yeast Asc1), uS2 (yeast S0), eS1 (yeast S1), uS5 (yeast S2), uS3 (yeast S3), eS4 (yeast S4), uS7 (yeast S5), eS6 (yeast S6), eS7 (yeast S7), eS8 (yeast S8), uS4 (yeast S9), eS10 (yeast S10), uS17 (yeast S11), eS12 (yeast S12), uS15 (yeast S13), uS11 (yeast S14), uS19 (yeast S15), uS9 (yeast S16), eS17 (yeast S17), uS13 (yeast S18), eS19 (yeast S19), uS10 (yeast S20), eS21 (yeast S21), uS8 (yeast S22), uS12 (yeast S23), eS24 (yeast S24), eS25 (yeast S25), eS26 (yeast S26), eS27 (yeast S27), eS28 (yeast S28), uS14 (yeast S29), eS30 (yeast S30), eS31 (yeast S31), yeast eEF2/RNA Complex
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUT
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE IV (ALMOST NON-ROTATED 40S SUBUNIT)
Descriptor:uL1 (yeast L1), uL2 (yeast L2), uL3 (yeast L3), uL4 (yeast L4), uL18 (yeast L5), eL6 (yeast L6), uL30 (yeast L7), eL8 (yeast L8), uL6 (yeast L9), uL16 (yeast L10), uL5 (yeast L11), uL11 (yeast L12), eL13 (yeast L13), eL14 (yeast L14), eL15 (yeast L15), uL13 (yeast L16), uL22 (yeast L17), eL18 (yeast L18), eL19 (yeast L19), eL20 (yeast L20), eL21 (yeast L21), eL22 (yeast L22), uL14 (yeast L23), eL24 (yeast L24), uL23 (yeast L25), uL24 (yeast L26), eL27 (yeast L27), uL15 (yeast L28), eL29 (yeast L29), eL30 (yeast L30), eL31 (yeast L31), eL32 (yeast L32), eL33 (yeast L33), eL34 (yeast L34), uL29 (yeast L35), eL36 (yeast L36), eL37 (yeast L37), eL38 (yeast L38), eL39 (yeast L39), eL40 (yeast L40), eL41 (yeast L41), eL42 (yeast L42), eL43 (yeast L43), uL10 (yeast P0), RACK1 (yeast Asc1), uS2 (yeast S0), eS1 (yeast S1), uS5 (yeast S2), uS3 (yeast S3), eS4 (yeast S4), uS7 (yeast S5), eS6 (yeast S6), eS7 (yeast S7), eS8 (yeast S8), uS4 (yeast S9), eS10 (yeast S10), uS17 (yeast S11), eS12 (yeast S12), uS15 (yeast S13), uS11 (yeast S14), uS19 (yeast S15), uS9 (yeast S16), eS17 (yeast S17), uS13 (yeast S18), eS19 (yeast S19), uS10 (yeast S20), eS21 (yeast S21), uS8 (yeast S22), uS12 (yeast S23), eS24 (yeast S24), eS25 (yeast S25), eS26 (yeast S26), eS27 (yeast S27), eS28 (yeast S28), uS14 (yeast S29), eS30 (yeast S30), eS31 (yeast S31), yeast eEF2/RNA Complex
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUU
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE V (LEAST ROTATED 40S SUBUNIT)
Descriptor:uL1 (yeast L1), uL2 (yeast L2), uL3 (yeast L3), uL4 (yeast L4), uL18 (yeast L5), eL6 (yeast L6), uL30 (yeast L7), eL8 (yeast L8), uL6 (yeast L9), uL16 (yeast L10), uL5 (yeast L11), uL11 (yeast L12), eL13 (yeast L13), eL14 (yeast L14), eL15 (yeast L15), uL13 (yeast L16), uL22 (yeast L17), eL18 (yeast L18), eL19 (yeast L19), eL20 (yeast L20), eL21 (yeast L21), eL22 (yeast L22), uL14 (yeast L23), eL24 (yeast L24), uL23 (yeast L25), uL24 (yeast L26), eL27 (yeast L27), uL15 (yeast L28), eL29 (yeast L29), eL30 (yeast L30), eL31 (yeast L31), eL32 (yeast L32), eL33 (yeast L33), eL34 (yeast L34), uL29 (yeast L35), eL36 (yeast L36), eL37 (yeast L37), eL38 (yeast L38), eL39 (yeast L39), eL40 (yeast L40), eL41 (yeast L41), eL42 (yeast L42), eL43 (yeast L43), uL10 (yeast P0), RACK1 (yeast Asc1), uS2 (yeast S0), eS1 (yeast S1), uS5 (yeast S2), uS3 (yeast S3), eS4 (yeast S4), uS7 (yeast S5), eS6 (yeast S6), eS7 (yeast S7), eS8 (yeast S8), uS4 (yeast S9), eS10 (yeast S10), uS17 (yeast S11), eS12 (yeast S12), uS15 (yeast S13), uS11 (yeast S14), uS19 (yeast S15), uS9 (yeast S16), eS17 (yeast S17), uS13 (yeast S18), eS19 (yeast S19), uS10 (yeast S20), eS21 (yeast S21), uS8 (yeast S22), uS12 (yeast S23), eS24 (yeast S24), eS25 (yeast S25), eS26 (yeast S26), eS27 (yeast S27), eS28 (yeast S28), uS14 (yeast S29), eS30 (yeast S30), eS31 (yeast S31), yeast eEF2/RNA Complex
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5KPS
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STRUCTURE OF RELA BOUND TO RIBOSOME IN ABSENCE OF A/R TRNA (STRUCTURE I)
Descriptor:GTP pyrophosphokinase, 50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L9, 50S ribosomal protein L10, 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L31, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36, 30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, 30S ribosomal protein S5, 30S ribosomal protein S6, 30S ribosomal protein S7, 30S ribosomal protein S8, 30S ribosomal protein S9, 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S13, 30S ribosomal protein S14, 30S ribosomal protein S15, 30S ribosomal protein S16, 30S ribosomal protein S17, 30S ribosomal protein S18, 30S ribosomal protein S19, 30S ribosomal protein S20, 30S ribosomal protein S21/RNA Complex
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:RibosomeRelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPV
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE II)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L9, 50S ribosomal protein L10, 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L31, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36, 30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, 30S ribosomal protein S5, 30S ribosomal protein S6, 30S ribosomal protein S7, 30S ribosomal protein S8, 30S ribosomal protein S9, 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S13, 30S ribosomal protein S14, 30S ribosomal protein S15, 30S ribosomal protein S16, 30S ribosomal protein S17, 30S ribosomal protein S18, 30S ribosomal protein S19, 30S ribosomal protein S20, 30S ribosomal protein S21, GTP pyrophosphokinase/RNA Complex
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:RibosomeRelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPW
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE III)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L9, 50S ribosomal protein L10, 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L31, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36, 30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, 30S ribosomal protein S5, 30S ribosomal protein S6, 30S ribosomal protein S7, 30S ribosomal protein S8, 30S ribosomal protein S9, 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S13, 30S ribosomal protein S14, 30S ribosomal protein S15, 30S ribosomal protein S16, 30S ribosomal protein S17, 30S ribosomal protein S18, 30S ribosomal protein S19, 30S ribosomal protein S20, 30S ribosomal protein S21, GTP pyrophosphokinase/RNA Complex
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:RibosomeRelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPX
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE IV)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L9, 50S ribosomal protein L10, 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L31, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36, 30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, 30S ribosomal protein S5, 30S ribosomal protein S6, 30S ribosomal protein S7, 30S ribosomal protein S8, 30S ribosomal protein S9, 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S13, 30S ribosomal protein S14, 30S ribosomal protein S15, 30S ribosomal protein S16, 30S ribosomal protein S17, 30S ribosomal protein S18, 30S ribosomal protein S19, 30S ribosomal protein S20, 30S ribosomal protein S21, GTP pyrophosphokinase/RNA Complex
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:RibosomeRelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5U9F
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3.2 A CRYO-EM ARFA-RF2 RIBOSOME RESCUE COMPLEX (STRUCTURE II)
Descriptor:ribosome
Authors:Demo, G., Svidritskiy, E., Madireddy, R., Diaz-Avalos, R., Grant, T., Grigorieff, N., Sousa, D., Korostelev, A.A.
Deposit date:2016-12-16
Release date:2017-03-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of ribosome rescue by ArfA and RF2
To Be Published
5U9G
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3.2 A CRYO-EM ARFA-RF2 RIBOSOME RESCUE COMPLEX (STRUCTURE I)
Descriptor:Ribosome
Authors:Demo, G., Svidritskiy, E., Madireddy, R., Diaz-Avalos, R., Grant, T., Grigorieff, N., Sousa, D., Korostelev, A.A.
Deposit date:2016-12-16
Release date:2017-03-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of ribosome rescue by ArfA and RF2
To Be Published
3SDM
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STRUCTURE OF OLIGOMERIC KINASE/RNASE IRE1 IN COMPLEX WITH AN OLIGONUCLEOTIDE
Descriptor:Serine/threonine-protein kinase/endoribonuclease IRE1 (E.C.2.7.11.1, 3.1.26.-)
Authors:Korennykh, A., Korostelev, A., Egea, P., Finer-Moore, J., Zhang, C., Stroud, R., Shokat, K., Walter, P.
Deposit date:2011-06-09
Release date:2011-07-13
Method:X-RAY DIFFRACTION (6.6 Å)
Cite:Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1.
Bmc Biol., 9, 2011
3SDJ
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STRUCTURE OF RNASE-INACTIVE POINT MUTANT OF OLIGOMERIC KINASE/RNASE IRE1
Descriptor:Serine/threonine-protein kinase/endoribonuclease IRE1 (E.C.2.7.11.1, 3.1.26.-)
Authors:Korennykh, A., Korostelev, A., Egea, P., Finer-Moore, J., Zhang, C., Stroud, R., Shokat, K., Walter, P.
Deposit date:2011-06-09
Release date:2011-07-13
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structural and functional basis for RNA cleavage by Ire1.
Bmc Biol., 9, 2011
4XEJ
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IRES BOUND TO BACTERIAL RIBOSOME
Descriptor:Ribosome
Authors:Zhu, J., Korostelev, A., Noller, H.F., Donohue, J.P.
Deposit date:2014-12-23
Release date:2015-02-25
Modification date:2016-09-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Initiation of translation in bacteria by a structured eukaryotic IRES RNA.
Nature, 519, 2015
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