Author results

3FBV
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CRYSTAL STRUCTURE OF THE OLIGOMER FORMED BY THE KINASE-RIBONUCLEASE DOMAIN OF IRE1
Descriptor:Serine/threonine-protein kinase/endoribonuclease IRE1, N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine
Authors:Korennykh, A.V., Egea, P.F., Korostelev, A.A., Finer-Moore, J., Zhang, C., Shokat, K.M., Stroud, R.M., Walter, P.
Deposit date:2008-11-19
Release date:2008-12-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The unfolded protein response signals through high-order assembly of Ire1.
Nature, 457, 2009
3J6X
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S. CEREVISIAE 80S RIBOSOME BOUND WITH TAURA SYNDROME VIRUS (TSV) IRES, 5 DEGREE ROTATION (CLASS II)
Descriptor:25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Koh, C.S., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J6Y
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S. CEREVISIAE 80S RIBOSOME BOUND WITH TAURA SYNDROME VIRUS (TSV) IRES, 2 DEGREE ROTATION (CLASS I)
Descriptor:25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Koh, C.S., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J77
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STRUCTURES OF YEAST 80S RIBOSOME-TRNA COMPLEXES IN THE ROTATED AND NON-ROTATED CONFORMATIONS (CLASS II - ROTATED RIBOSOME WITH 1 TRNA)
Descriptor:60S ribosomal protein L1, 60S ribosomal protein L2, 60S ribosomal protein L3, ...
Authors:Svidritskiy, E., Brilot, A.F., Koh, C.S., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
3J78
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STRUCTURES OF YEAST 80S RIBOSOME-TRNA COMPLEXES IN THE ROTATED AND NON-ROTATED CONFORMATIONS (CLASS I - NON-ROTATED RIBOSOME WITH 2 TRNAS)
Descriptor:60S ribosomal protein L1, 60S ribosomal protein L2, 60S ribosomal protein L3, ...
Authors:Svidritskiy, E., Brilot, A.F., Koh, C.S., Grigorieff, N., Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
4V7C
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STRUCTURE OF THE RIBOSOME WITH ELONGATION FACTOR G TRAPPED IN THE PRE-TRANSLOCATION STATE (PRE-TRANSLOCATION 70S*TRNA STRUCTURE)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Brilot, A.F., Korostelev, A.A., Ermolenko, D.N., Grigorieff, N.
Deposit date:2013-11-20
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V7D
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STRUCTURE OF THE RIBOSOME WITH ELONGATION FACTOR G TRAPPED IN THE PRE-TRANSLOCATION STATE (PRE-TRANSLOCATION 70S*TRNA*EF-G STRUCTURE)
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L1, ...
Authors:Brilot, A.F., Korostelev, A.A., Ermolenko, D.N., Grigorieff, N.
Deposit date:2013-11-21
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V9N
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CRYSTAL STRUCTURE OF THE 70S RIBOSOME BOUND WITH THE Q253P MUTANT OF RELEASE FACTOR RF2.
Descriptor:16S rRNA (1504-MER), messenger RNA (5'-R(*AP*AP*UP*GP*UP*AP*G)-3'), P-site tRNA-fMet, ...
Authors:Santos, N., Zhu, J., Donohue, J.P., Korostelev, A.A., Noller, H.F.
Deposit date:2013-04-26
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2.
Structure, 21, 2013
4V9Q
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CRYSTAL STRUCTURE OF BLASTICIDIN S BOUND TO THERMUS THERMOPHILUS 70S RIBOSOME.
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Svidritskiy, E., Ling, C., Ermolenko, D.N., Korostelev, A.A.
Deposit date:2013-06-12
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 110, 2013
5D8B
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CRYSTAL STRUCTURE OF T. THERMOPHILUS RIBOSOME CONTAINING A P-SITE WOBBLE MISMATCH
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Svidritskiy, E., Korostelev, A.A.
Deposit date:2015-08-17
Release date:2015-10-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.63 Å)
Cite:Ribosome Structure Reveals Preservation of Active Sites in the Presence of a P-Site Wobble Mismatch.
Structure, 23, 2015
5J4D
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E. COLI RELEASE FACTOR 1 BOUND TO THE 70S RIBOSOME IN RESPONSE TO A PSEUDOURIDYLATED STOP CODON
Descriptor:16S ribosomal RNA, 25S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Svidritskiy, E., Korostelev, A.A.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Translation Termination on a Pseudouridylated Stop Codon.
J.Mol.Biol., 428, 2016
5JUO
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE I (FULLY ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUP
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE II (MID-ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUS
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE III (MID-ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUT
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE IV (ALMOST NON-ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5JUU
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SACCHAROMYCES CEREVISIAE 80S RIBOSOME BOUND WITH ELONGATION FACTOR EEF2-GDP-SORDARIN AND TAURA SYNDROME VIRUS IRES, STRUCTURE V (LEAST ROTATED 40S SUBUNIT)
Descriptor:18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P., Koh, C.S., Grant, T., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5KPS
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STRUCTURE OF RELA BOUND TO RIBOSOME IN ABSENCE OF A/R TRNA (STRUCTURE I)
Descriptor:GTP pyrophosphokinase, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPV
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE II)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPW
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE III)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5KPX
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STRUCTURE OF RELA BOUND TO RIBOSOME IN PRESENCE OF A/R TRNA (STRUCTURE IV)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Loveland, A.B., Bah, E., Madireddy, R., Zhang, Y., Brilot, A.F., Grigorieff, N., Korostelev, A.A.
Deposit date:2016-07-05
Release date:2016-09-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
5TWJ
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CRYSTAL STRUCTURE OF RLMH IN COMPLEX WITH S-ADENOSYLMETHIONINE
Descriptor:Ribosomal RNA large subunit methyltransferase H, S-ADENOSYLMETHIONINE
Authors:Koh, C.S., Madireddy, R., Beane, T.J., Zamore, P.D., Korostelev, A.A.
Deposit date:2016-11-14
Release date:2017-05-03
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine.
Sci Rep, 7, 2017
5TWK
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CRYSTAL STRUCTURE OF RLMH IN COMPLEX WITH SINEFUNGIN
Descriptor:Ribosomal RNA large subunit methyltransferase H, SINEFUNGIN
Authors:Koh, C.S., Madireddy, R., Beane, T.J., Zamore, P.D., Korostelev, A.A.
Deposit date:2016-11-14
Release date:2017-05-03
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine.
Sci Rep, 7, 2017
5U9F
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3.2 A CRYO-EM ARFA-RF2 RIBOSOME RESCUE COMPLEX (STRUCTURE II)
Descriptor:16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Demo, G., Svidritskiy, E., Madireddy, R., Diaz-Avalos, R., Grant, T., Grigorieff, N., Sousa, D., Korostelev, A.A.
Deposit date:2016-12-16
Release date:2017-03-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of ribosome rescue by ArfA and RF2.
Elife, 6, 2017
5U9G
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3.2 A CRYO-EM ARFA-RF2 RIBOSOME RESCUE COMPLEX (STRUCTURE I)
Descriptor:16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Demo, G., Svidritskiy, E., Madireddy, R., Diaz-Avalos, R., Grant, T., Grigorieff, N., Sousa, D., Korostelev, A.A.
Deposit date:2016-12-16
Release date:2017-03-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of ribosome rescue by ArfA and RF2.
Elife, 6, 2017
5UYK
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70S RIBOSOME BOUND WITH COGNATE TERNARY COMPLEX NOT BASE-PAIRED TO A SITE CODON (STRUCTURE I)
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Loveland, A.B., Demo, G., Grigorieff, N., Korostelev, A.A.
Deposit date:2017-02-24
Release date:2017-06-07
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
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