1EXM | | CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP. | | 分子名称: | ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Hogg, T., Mesters, J.R., Hilgenfeld, R. | | 登録日 | 2000-05-03 | | 公開日 | 2000-06-07 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Insights into the GTPase Mechanism of EF-Tu from Structural Studies
The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions, 28, 2000
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5IDK | |
1HA3 | | ELONGATION FACTOR TU IN COMPLEX WITH AURODOX | | 分子名称: | ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Vogeley, L., Palm, G.J., Mesters, J.R., Hilgenfeld, R. | | 登録日 | 2001-03-26 | | 公開日 | 2001-05-15 | | 最終更新日 | 2019-10-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformational Change of Elongation Factor TU Induced by Antibiotic Binding: Crystal Structure of the Complex between EF-TU:Gdp and Aurodox
J.Biol.Chem., 276, 2001
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1LK9 | | THE THREE-DIMENSIONAL STRUCTURE OF ALLIINASE FROM GARLIC | | 分子名称: | ALLIIN LYASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kuettner, E.B., Hilgenfeld, R., Weiss, M.S. | | 登録日 | 2002-04-24 | | 公開日 | 2002-12-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The active principle of garlic at atomic resolution
J.Biol.Chem., 277, 2002
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1F13 | |
1VIJ | | HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR HOE/BAY 793 HEXAGONAL FORM | | 分子名称: | HIV-1 PROTEASE, N-(1-BENZYL-2,3-DIHYDROXY-4-{3-METHYL-2-[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYLAMINO]-BUTYRYLAMINO}-5-PHENYL-PENTYL)-3-METHYL-2-[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYLAMINO]-BUTYRAMIDE | | 著者 | Lange-Savage, G., Berchtold, H., Liesum, A., Hilgenfeld, R. | | 登録日 | 1997-05-07 | | 公開日 | 1999-01-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of HOE/BAY 793 complexed to human immunodeficiency virus (HIV-1) protease in two different crystal forms--structure/function relationship and influence of crystal packing.
Eur.J.Biochem., 248, 1997
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1VIK | | HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR HOE/BAY 793 ORTHORHOMBIC FORM | | 分子名称: | HIV-1 PROTEASE, N-(1-BENZYL-2,3-DIHYDROXY-4-{3-METHYL-2-[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYLAMINO]-BUTYRYLAMINO}-5-PHENYL-PENTYL)-3-METHYL-2-[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYLAMINO]-BUTYRAMIDE | | 著者 | Lange-Savage, G., Berchtold, H., Liesum, A., Hilgenfeld, R. | | 登録日 | 1997-05-07 | | 公開日 | 1998-12-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of HOE/BAY 793 complexed to human immunodeficiency virus (HIV-1) protease in two different crystal forms--structure/function relationship and influence of crystal packing.
Eur.J.Biochem., 248, 1997
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2CIJ | | MEMBRANE-BOUND GLUTAMATE CARBOXYPEPTIDASE II (GCPII) WITH BOUND METHIONINE | | 分子名称: | GLUTAMATE CARBOXYPEPTIDASE II, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Barinka, C., Plechanovova, A., Rulisek, L., Mlcochova, P., Majer, P., Slusher, B.S., Hilgenfeld, R., Mesters, J.R., Konvalinka, J. | | 登録日 | 2006-03-21 | | 公開日 | 2007-03-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Glutamate Carboxypeptidase II
Handbook of Metalloproteins, 4, 2011
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2JBJ | | MEMBRANE-BOUND GLUTAMATE CARBOXYPEPTIDASE II (GCPII) IN COMPLEX WITH 2-PMPA (2-PHOSPHONOMETHYL-PENTANEDIOIC ACID) | | 分子名称: | GLUTAMATE CARBOXYPEPTIDASE 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Mesters, J.R., Henning, K., Hilgenfeld, R. | | 登録日 | 2006-12-07 | | 公開日 | 2006-12-18 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Human Glutamate Carboxypeptidase II Inhibition: Structures of Gcpii in Complex with Two Potent Inhibitors, Quisqualate and 2-Pmpa.
Acta Crystallogr.,Sect.D, 63, 2007
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2JBK | | MEMBRANE-BOUND GLUTAMATE CARBOXYPEPTIDASE II (GCPII) IN COMPLEX WITH QUISQUALIC ACID (QUISQUALATE, ALPHA-AMINO-3,5-DIOXO-1,2,4- OXADIAZOLIDINE-2-PROPANOIC ACID) | | 分子名称: | GLUTAMATE CARBOXYPEPTIDASE 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Mesters, J.R., Henning, K., Hilgenfeld, R. | | 登録日 | 2006-12-07 | | 公開日 | 2006-12-18 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Human Glutamate Carboxypeptidase II Inhibition: Structures of Gcpii in Complex with Two Potent Inhibitors, Quisqualate and 2-Pmpa.
Acta Crystallogr.,Sect.D, 63, 2007
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2Q8W | |
2XCI | | MEMBRANE-EMBEDDED MONOFUNCTIONAL GLYCOSYLTRANSFERASE WAAA OF AQUIFEX AEOLICUS, SUBSTRATE-FREE FORM | | 分子名称: | 3-DEOXY-D-MANNO-2-OCTULOSONIC ACID TRANSFERASE, TETRAETHYLENE GLYCOL, GLYCEROL, ... | | 著者 | Schmidt, H., Hansen, G., Hilgenfeld, R., Mamat, U., Mesters, J.R. | | 登録日 | 2010-04-26 | | 公開日 | 2011-05-11 | | 最終更新日 | 2019-05-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Mechanistic Analysis of the Membrane-Embedded Glycosyltransferase Waaa Required for Lipopolysaccharide Synthesis.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2XCU | | MEMBRANE-EMBEDDED MONOFUNCTIONAL GLYCOSYLTRANSFERASE WAAA OF AQUIFEX AEOLICUS, COMPLEX WITH CMP | | 分子名称: | 3-DEOXY-D-MANNO-2-OCTULOSONIC ACID TRANSFERASE, CYTIDINE-5'-MONOPHOSPHATE, PENTAETHYLENE GLYCOL, ... | | 著者 | Schmidt, H., Hansen, G., Hilgenfeld, R., Mamat, U., Mesters, J.R. | | 登録日 | 2010-04-26 | | 公開日 | 2011-05-11 | | 最終更新日 | 2019-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structural and Mechanistic Analysis of the Membrane-Embedded Glycosyltransferase Waaa Required for Lipopolysaccharide Synthesis.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2J97 | | HUMAN CORONAVIRUS 229E NON STRUCTURAL PROTEIN 9 (NSP9) | | 分子名称: | REPLICASE POLYPROTEIN 1AB, (4S)-2-METHYL-2,4-PENTANEDIOL, SULFATE ION | | 著者 | Ponnusamy, R., Mesters, J.R., Moll, R., Hilgenfeld, R. | | 登録日 | 2006-11-03 | | 公開日 | 2007-11-27 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Variable Oligomerization Modes in Coronavirus Non-Structural Protein 9.
J.Mol.Biol., 383, 2008
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2J98 | | HUMAN CORONAVIRUS 229E NON STRUCTURAL PROTEIN 9 CYS69ALA MUTANT (NSP9) | | 分子名称: | REPLICASE POLYPROTEIN 1AB, 2,3-DIHYDROXY-1,4-DITHIOBUTANE | | 著者 | Ponnusamy, R., Mesters, J.R., Moll, R., Hilgenfeld, R. | | 登録日 | 2006-11-03 | | 公開日 | 2007-11-27 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Variable Oligomerization Modes in Coronavirus Non-Structural Protein 9.
J.Mol.Biol., 383, 2008
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2VB0 | | CRYSTAL STRUCTURE OF COXSACKIEVIRUS B3 PROTEINASE 3C | | 分子名称: | POLYPROTEIN 3BCD, CHLORIDE ION | | 著者 | Anand, K., Mesters, J.R., Goerlach, R., Zell, R., Hilgenfeld, R. | | 登録日 | 2007-09-05 | | 公開日 | 2008-10-28 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of Coxsackie Virus B3 Proteinase 3C
To be Published
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1JFX | | CRYSTAL STRUCTURE OF THE BACTERIAL LYSOZYME FROM STREPTOMYCES COELICOLOR AT 1.65 A RESOLUTION | | 分子名称: | 1,4-beta-N-Acetylmuramidase M1, CHLORIDE ION | | 著者 | Rau, A., Hogg, T., Marquardt, R., Hilgenfeld, R. | | 登録日 | 2001-06-22 | | 公開日 | 2001-09-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | A new lysozyme fold. Crystal structure of the muramidase from Streptomyces coelicolor at 1.65 A resolution.
J.Biol.Chem., 276, 2001
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2VRI | |
3O5Z | | CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM P85BETA SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE (PI3K) | | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit beta, CHLORIDE ION, (4S)-2-METHYL-2,4-PENTANEDIOL | | 著者 | Chen, S., Xiao, Y., Ponnusamy, R., Tan, J., Lei, J., Hilgenfeld, R. | | 登録日 | 2010-07-28 | | 公開日 | 2011-08-10 | | 最終更新日 | 2014-09-10 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | X-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85 beta subunit
Acta Crystallogr.,Sect.F, 67, 2011
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3P31 | |
3PV2 | |
3PV3 | | STRUCTURE OF LEGIONELLA FALLONII DEGQ (S193A VARIANT) | | 分子名称: | DegQ, Substrate peptide (Poly-Ala) | | 著者 | Wrase, R., Scott, H., Hilgenfeld, R., Hansen, G. | | 登録日 | 2010-12-06 | | 公開日 | 2011-06-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3PV4 | | STRUCTURE OF LEGIONELLA FALLONII DEGQ (DELTA-PDZ2 VARIANT) | | 分子名称: | DegQ, CADMIUM ION | | 著者 | Wrase, R., Scott, H., Hilgenfeld, R., Hansen, G. | | 登録日 | 2010-12-06 | | 公開日 | 2011-06-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3PV5 | |
4YNN | | STRUCTURE OF LEGIONELLA PNEUMOPHILA DEGQ (S190A VARIANT) | | 分子名称: | Protease DO, Octapeptide, Hexa-peptide, ... | | 著者 | Wrase, R., Hilgenfeld, R., Hansen, G. | | 登録日 | 2015-03-10 | | 公開日 | 2015-06-24 | | 最終更新日 | 2015-08-26 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structures of DegQ from Legionella pneumophila Define Distinct ON and OFF States.
J.Mol.Biol., 427, 2015
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