8AIZ

Mpro of SARS-CoV-2 in complex with the RK-68 inhibitor

This is a non-PDB format compatible entry.

Summary for 8AIZ

• Entry DOI: 10.2210/pdb8aiz/pdb
• Descriptor: Replicase polyprotein 1ab, (2~{R},3~{S})-3-[[(2~{S})-3-cyclopropyl-2-[2-oxidanylidene-3-(2-phenylethanoylamino)pyridin-1-yl]propanoyl]amino]-~{N}-methyl-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butanamide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: inhibitor complex, sars-cov2, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus
• Total number of polymer chains: 1
• Total formula weight: 34398.61

Authors

El Kilani, H.,Hilgenfeld, R. (deposition date: 2022-07-27, release date: 2023-08-16)

• Primary citation: EL Kilani, H.,Hilgenfeld, R.; Main Protease SARS-CoV-2 in complex with the inhibitor RK-68; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.992 Å)