Author results

2GEJ
  • Download 2gej
  • View 2gej
Molmil generated image of 2gej
CRYSTAL STRUCTURE OF PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE (PIMA) FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH GDP-MAN
Descriptor:PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE (PimA), GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE
Authors:Guerin, M.E., Buschiazzo, A., Kordulakova, J., Jackson, M., Alzari, P.M.
Deposit date:2006-03-20
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.
J.Biol.Chem., 282, 2007
2GEK
  • Download 2gek
  • View 2gek
Molmil generated image of 2gek
CRYSTAL STRUCTURE OF PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE (PIMA) FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH GDP
Descriptor:PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE (PimA), GUANOSINE-5'-DIPHOSPHATE
Authors:Guerin, M.E., Buschiazzo, A., Kordulakova, J., Jackson, M., Alzari, P.M.
Deposit date:2006-03-20
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.
J.Biol.Chem., 282, 2007
1RZU
  • Download 1rzu
  • View 1rzu
Molmil generated image of 1rzu
CRYSTAL STRUCTURE OF THE GLYCOGEN SYNTHASE FROM A. TUMEFACIENS IN COMPLEX WITH ADP
Descriptor:Glycogen synthase 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Buschiazzo, A., Guerin, M.E., Ugalde, J.E., Ugalde, R.A., Shepard, W., Alzari, P.M.
Deposit date:2003-12-29
Release date:2004-08-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation.
Embo J., 23, 2004
1RZV
  • Download 1rzv
  • View 1rzv
Molmil generated image of 1rzv
CRYSTAL STRUCTURE OF THE GLYCOGEN SYNTHASE FROM AGROBACTERIUM TUMEFACIENS (NON-COMPLEXED FORM)
Descriptor:Glycogen synthase 1
Authors:Buschiazzo, A., Guerin, M.E., Ugalde, J.E., Ugalde, R.A., Shepard, W., Alzari, P.M.
Deposit date:2003-12-29
Release date:2004-08-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation.
Embo J., 23, 2004
4A0X
  • Download 4a0x
  • View 4a0x
Molmil generated image of 4a0x
STRUCTURE OF THE GLOBAL TRANSCRIPTION REGULATOR FAPR FROM STAPHYLOCOCCUS AUREUS
Descriptor:TRANSCRIPTION FACTOR FAPR, ZINC ION, ACETATE ION, ...
Authors:Albanesi, D., Guerin, M.E., Buschiazzo, A., de Mendoza, D., Alzari, P.M.
Deposit date:2011-09-13
Release date:2012-09-26
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus.
Plos Pathog., 9, 2013
4A0Y
  • Download 4a0y
  • View 4a0y
Molmil generated image of 4a0y
STRUCTURE OF THE GLOBAL TRANSCRIPTION REGULATOR FAPR FROM STAPHYLOCOCCUS AUREUS
Descriptor:TRANSCRIPTION FACTOR FAPR, CHLORIDE ION
Authors:Albanesi, D., Guerin, M.E., Buschiazzo, A., de Mendoza, D., Alzari, P.M.
Deposit date:2011-09-13
Release date:2012-09-26
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus.
Plos Pathog., 9, 2013
4A0Z
  • Download 4a0z
  • View 4a0z
Molmil generated image of 4a0z
STRUCTURE OF THE GLOBAL TRANSCRIPTION REGULATOR FAPR FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH MALONYL-COA
Descriptor:TRANSCRIPTION FACTOR FAPR, MALONYL-COENZYME A
Authors:Albanesi, D., Guerin, M.E., Buschiazzo, A., de Mendoza, D., Alzari, P.M.
Deposit date:2011-09-13
Release date:2012-09-26
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus.
Plos Pathog., 9, 2013
4A12
  • Download 4a12
  • View 4a12
Molmil generated image of 4a12
STRUCTURE OF THE GLOBAL TRANSCRIPTION REGULATOR FAPR FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH DNA OPERATOR
Descriptor:TRANSCRIPTION FACTOR FAPR, FAPR PROMOTER
Authors:Albanesi, D., Guerin, M.E., Buschiazzo, A., de Mendoza, D., Alzari, P.M.
Deposit date:2011-09-13
Release date:2012-09-26
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus.
Plos Pathog., 9, 2013
4A21
  • Download 4a21
  • View 4a21
Molmil generated image of 4a21
STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE BOUND TO SULFATE
Descriptor:FRUCTOSE-BISPHOSPHATE ALDOLASE, SULFATE ION, SODIUM ION
Authors:Coincon, M., De la Paz Santangelo, M., Gest, P.M., Guerin, M.E., Pham, H., Ryan, G., Puckett, S.E., Spencer, J.S., Gonzalez-Juarrero, M., Daher, R., Lenaerts, A.J., Schnappinger, D., Therisod, M., Ehrt, S., Jackson, M., Sygusch, J.
Deposit date:2011-09-21
Release date:2011-10-05
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Glycolytic and Non-Glycolytic Functions of the Fructose-1,6-Bisphosphate Aldolase of Mycobacterium Tuberculosis, an Essential Enzyme Produced by Replicating and Non-Replicating Bacilli
J.Biol.Chem., 286, 2011
4A22
  • Download 4a22
  • View 4a22
Molmil generated image of 4a22
STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE BOUND TO N-(4-HYDROXYBUTYL)- GLYCOLOHYDROXAMIC ACID BIS- PHOSPHATE
Descriptor:FRUCTOSE-BISPHOSPHATE ALDOLASE, 4-{hydroxy[(phosphonooxy)acetyl]amino}butyl dihydrogen phosphate, SODIUM ION, ...
Authors:Coincon, M., De la Paz Santangelo, M., Gest, P.M., Guerin, M.E., Pham, H., Ryan, G., Puckett, S.E., Spencer, J.S., Gonzalez-Juarrero, M., Daher, R., Lenaerts, A.J., Schnappinger, D., Therisod, M., Ehrt, S., Jackson, M., Sygusch, J.
Deposit date:2011-09-21
Release date:2011-10-12
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.
J. Biol. Chem., 286, 2011
4DDZ
  • Download 4ddz
  • View 4ddz
Molmil generated image of 4ddz
CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE (GpgS), GLYCEROL
Authors:Albesa-Jove, D., Urresti, S., Gest, P.M., van der Woerd, M., Jackson, M., Guerin, M.E.
Deposit date:2012-01-19
Release date:2012-06-06
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria.
J.Biol.Chem., 287, 2012
4DE7
  • Download 4de7
  • View 4de7
Molmil generated image of 4de7
CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MG2+ AND URIDINE-DIPHOSPHATE (UDP)
Descriptor:GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE (GpgS), URIDINE-5'-DIPHOSPHATE, GLYCEROL
Authors:Albesa-Jove, D., Urresti, S., van der Woerd, M., Guerin, M.E.
Deposit date:2012-01-20
Release date:2012-06-06
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria.
J.Biol.Chem., 287, 2012
4DEC
  • Download 4dec
  • View 4dec
Molmil generated image of 4dec
CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE (UDP) AND PHOSPHOGLYCERIC ACID (PGA)
Descriptor:GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE (GpgS), URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Albesa-Jove, D., Urresti, S., van der Woerd, M., Guerin, M.E.
Deposit date:2012-01-20
Release date:2012-06-06
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria.
J.Biol.Chem., 287, 2012
4N9W
  • Download 4n9w
  • View 4n9w
Molmil generated image of 4n9w
CRYSTAL STRUCTURE OF PHOSPHATIDYL MANNOSYLTRANSFERASE PIMA
Descriptor:GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase, GUANOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL
Authors:Giganti, D., Albesa-Jove, D., Bellinzoni, M., Guerin, M.E., Alzari, P.M.
Deposit date:2013-10-21
Release date:2014-11-12
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Secondary structure reshuffling modulates glycosyltransferase function at the membrane.
Nat.Chem.Biol., 11, 2015
4NC9
  • Download 4nc9
  • View 4nc9
Molmil generated image of 4nc9
CRYSTAL STRUCTURE OF PHOSPHATIDYL MANNOSYLTRANSFERASE PIMA
Descriptor:GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase
Authors:Giganti, D., Albesa-Jove, D., Bellinzoni, M., Guerin, M.E., Alzari, P.M.
Deposit date:2013-10-24
Release date:2014-11-12
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (3.192 Å)
Cite:Secondary structure reshuffling modulates glycosyltransferase function at the membrane.
Nat.Chem.Biol., 11, 2015
4NXI
  • Download 4nxi
  • View 4nxi
Molmil generated image of 4nxi
RV2466C MEDIATES THE ACTIVATION OF TP053 TO KILL REPLICATING AND NON-REPLICATING MYCOBACTERIUM TUBERCULOSIS
Descriptor:Uncharacterized protein, MAGNESIUM ION, 1,2-ETHANEDIOL
Authors:Albesa-Jove, D., Urresti, S., Comino, N., Guerin, M.E.
Deposit date:2013-12-09
Release date:2014-10-22
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
4NY2
  • Download 4ny2
  • View 4ny2
Molmil generated image of 4ny2
STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH ACETATE ION (ACT) IN P 21
Descriptor:Deacetylase DA1, ZINC ION, CALCIUM ION, ...
Authors:Albesa-Jove, D., Andres, E., Biarnes, X., Planas, A., Guerin, M.E.
Deposit date:2013-12-10
Release date:2014-08-13
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (1.879 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NYU
  • Download 4nyu
  • View 4nyu
Molmil generated image of 4nyu
STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH ACETATE ION (ACT) IN C 2 2 21
Descriptor:Deacetylase DA1, ZINC ION, CALCIUM ION, ...
Authors:Albesa-Jove, D., Andres, E., Biarnes, X., Planas, A., Guerin, M.E.
Deposit date:2013-12-11
Release date:2014-08-13
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NYY
  • Download 4nyy
  • View 4nyy
Molmil generated image of 4nyy
STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH ACETATE ION (ACT) IN P 2 21 21
Descriptor:Deacetylase DA1, ZINC ION, SODIUM ION, ...
Authors:Albesa-Jove, D., Andres, E., Biarnes, X., Planas, A., Guerin, M.E.
Deposit date:2013-12-11
Release date:2014-08-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NZ1
  • Download 4nz1
  • View 4nz1
Molmil generated image of 4nz1
STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH DI(N-ACETYL-D-GLUCOSAMINE) (CBS) IN P 21
Descriptor:Deacetylase DA1, ZINC ION, CALCIUM ION, ...
Authors:Albesa-Jove, D., Andres, E., Biarnes, X., Planas, A., Guerin, M.E.
Deposit date:2013-12-11
Release date:2014-08-13
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NZ3
  • Download 4nz3
  • View 4nz3
Molmil generated image of 4nz3
STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH DI(N-ACETYL-D-GLUCOSAMINE) (CBS) IN P 21 21 21
Descriptor:Deacetylase DA1, ZINC ION, MAGNESIUM ION, ...
Authors:Albesa-Jove, D., Andres, E., Biarnes, X., Planas, A., Guerin, M.E.
Deposit date:2013-12-11
Release date:2014-08-13
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (2.114 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NZ4
  • Download 4nz4
  • View 4nz4
Molmil generated image of 4nz4
STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE (NDG) AND ZINC ION
Descriptor:Deacetylase DA1, ZINC ION, CALCIUM ION, ...
Authors:Albesa-Jove, D., Andres, E., Biarnes, X., Planas, A., Guerin, M.E.
Deposit date:2013-12-11
Release date:2014-08-13
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (1.944 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NZ5
  • Download 4nz5
  • View 4nz5
Molmil generated image of 4nz5
STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE (NDG) AND CADMIUM ION
Descriptor:Deacetylase DA1, SODIUM ION, CADMIUM ION, ...
Authors:Albesa-Jove, D., Andres, E., Biarnes, X., Planas, A., Guerin, M.E.
Deposit date:2013-12-11
Release date:2014-11-26
Method:X-RAY DIFFRACTION (1.874 Å)
Cite:Vibrio cholerae protein
To be Published
4OUI
  • Download 4oui
  • View 4oui
Molmil generated image of 4oui
STRUCTURE OF VIBRIO CHOLERAE CHITIN DE-N-ACETYLASE IN COMPLEX WITH TRIACETYLCHITOTRIOSE (CTO)
Descriptor:Deacetylase DA1, ZINC ION, MAGNESIUM ION, ...
Authors:Albesa-Jove, D., Andres, E., Biarnes, X., Planas, A., Guerin, M.E.
Deposit date:2014-02-17
Release date:2014-08-13
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
4Y6N
  • Download 4y6n
  • View 4y6n
Molmil generated image of 4y6n
CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND PHOSPHOGLYCERIC ACID (PGA) - GPGS MN2+ UDP-GLC PGA-1
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, 3-PHOSPHOGLYCERIC ACID, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-13
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.348 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
<123>