6Z2P

Crystal structure of catalytic inactive OgpA from Akkermansia muciniphila in complex with an O-glycopeptide (glycodrosocin) substrate

Summary for 6Z2P

Entry DOI	10.2210/pdb6z2p/pdb
Related PRD ID	PRD_900084
Descriptor	O-glycan protease, Glycodrosocin, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, ... (5 entities in total)
Functional Keywords	o-glycan endopeptidase, mucins, ogpa. metalloprotease, hydrolase
Biological source	Akkermansia muciniphila ATCC BAA-835 More
Total number of polymer chains	2
Total formula weight	44359.04
Authors	Trastoy, B.,Naegali, A.,Anso, I.,Sjogren, J.,Guerin, M.E. (deposition date: 2020-05-18, release date: 2020-09-30, Last modification date: 2024-01-24)
Primary citation	Trastoy, B.,Naegeli, A.,Anso, I.,Sjogren, J.,Guerin, M.E. Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila. Nat Commun, 11:4844-4844, 2020 Cited by PubMed: 32973204 DOI: 10.1038/s41467-020-18696-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation