6Z2P
Crystal structure of catalytic inactive OgpA from Akkermansia muciniphila in complex with an O-glycopeptide (glycodrosocin) substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | O-glycan protease | polymer | 371 | 41731.0 | 1 | UniProt (B2UR60) | Akkermansia muciniphila ATCC BAA-835 | |
| 2 | B (C) | Glycodrosocin | polymer | 19 | 2204.6 | 1 | UniProt (by SIFTS) (P36193) | synthetic construct | |
| 3 | C (B) | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | branched | 383.3 | 1 | In PDB BIRD (PRD_900084) GlyTouCan (G00031MO) | Thomsen-Friedenreich antigen | ||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F (A, C) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A: 25 - 385 (UniProt: B2UR60)
| PDB | External Database | Details |
|---|---|---|
| Met 24 | - | initiating methionine |
| Ala 205 | His 205 | engineered mutation |
| Ala 206 | Glu 206 | engineered mutation |
| Gly 386 | - | expression tag |
| Ser 387 | - | expression tag |
| Gly 388 | - | expression tag |
| His 389 | - | expression tag |
| His 390 | - | expression tag |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
| His 393 | - | expression tag |
| His 394 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43935.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 383.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 44359.0 |
