2GEK

Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP

Summary for 2GEK

• Entry DOI: 10.2210/pdb2gek/pdb
• Related: 2GEJ
• Descriptor: PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE (PimA), GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: gt4 glycosyltransferase, mannosyltransferase, rossmann fold, binary complex, transferase
• Biological source: Mycobacterium smegmatis
• Cellular location: Cell membrane; Single-pass membrane protein (Potential): A0QWG6
• Total number of polymer chains: 1
• Total formula weight: 43883.49

Authors

Guerin, M.E.,Buschiazzo, A.,Kordulakova, J.,Jackson, M.,Alzari, P.M. (deposition date: 2006-03-20, release date: 2007-04-03, Last modification date: 2024-02-14)

• Primary citation: Guerin, M.E.,Kordulakova, J.,Schaeffer, F.,Svetlikova, Z.,Buschiazzo, A.,Giganti, D.,Gicquel, B.,Mikusova, K.,Jackson, M.,Alzari, P.M.; Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.; J.Biol.Chem., 282:20705-20714, 2007; PubMed: 17510062; DOI: 10.1074/jbc.M702087200

Experimental method

X-RAY DIFFRACTION (2.4 Å)