2GEK

Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000030	molecular_function	mannosyltransferase activity
A	0004377	molecular_function	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0009247	biological_process	glycolipid biosynthetic process
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0043750	molecular_function	phosphatidylinositol alpha-mannosyltransferase activity
A	0046488	biological_process	phosphatidylinositol metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GDP A 2567

Chain	Residue
A	PRO14
A	LYS256
A	ILE278
A	VAL279
A	GLU282
A	GLY15
A	GLY16
A	LEU194
A	LYS202
A	GLN250
A	VAL251
A	ASP252
A	ASP253

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17510062","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17510062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19520856","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19520856","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17510062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19520856","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17510062","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Site: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"17510062","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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