Author results

1ZN0
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COORDINATES OF RRF AND EF-G FITTED INTO CRYO-EM MAP OF THE 50S SUBUNIT BOUND WITH BOTH EF-G (GDPNP) AND RRF
Descriptor:16S RIBOSOMAL RNA, Ribosome recycling factor, ELONGATION FACTOR G
Authors:Gao, N., Zavialov, A.V., Li, W., Sengupta, J., Valle, M., Gursky, R.P., Ehrenberg, M., Frank, J.
Deposit date:2005-05-11
Release date:2005-06-14
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (15.5 Å)
Cite:Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies.
Mol.Cell, 18, 2005
1ZN1
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COORDINATES OF RRF FITTED INTO CRYO-EM MAP OF THE 70S POST-TERMINATION COMPLEX
Descriptor:ribosomal 23S RNA, ribosomal 16S RNA, Ribosome recycling factor, ...
Authors:Gao, N., Zavialov, A.V., Li, W., Sengupta, J., Valle, M., Gursky, R.P., Ehrenberg, M., Frank, J.
Deposit date:2005-05-11
Release date:2005-06-14
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies.
Mol.Cell, 18, 2005
2RDO
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50S SUBUNIT WITH EF-G(GDPNP) AND RRF BOUND
Descriptor:5S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 50S ribosomal protein L25, ...
Authors:Gao, N., Zavialov, A.V., Ehrenberg, M., Frank, J.
Deposit date:2007-09-24
Release date:2008-03-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
3PN1
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NOVEL BACTERIAL NAD+-DEPENDENT DNA LIGASE INHIBITORS WITH BROAD SPECTRUM POTENCY AND ANTIBACTERIAL EFFICACY IN VIVO
Descriptor:DNA ligase, 2-(butylsulfanyl)adenosine, 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide
Authors:Mills, S., Eakin, A., Buurman, E., Newman, J., Gao, N., Huynh, H., Johnson, K., Lahiri, S., Shapiro, A., Walkup, G., Wei, Y., Stokes, S.
Deposit date:2010-11-18
Release date:2011-01-12
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel Bacterial NAD+-Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy In Vivo.
Antimicrob.Agents Chemother., 55, 2011
2YKR
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30S RIBOSOMAL SUBUNIT WITH RSGA BOUND IN THE PRESENCE OF GMPPNP
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Guo, Q., Yuan, Y., Xu, Y., Feng, B., Liu, L., Chen, K., Lei, J., Gao, N.
Deposit date:2011-05-30
Release date:2011-08-24
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TWD
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GLMUC1 IN COMPLEX WITH AN ANTIBACTERIAL INHIBITOR
Descriptor:Bifunctional protein glmU, SULFATE ION, 4-({5-[(4-aminophenyl)(phenyl)sulfamoyl]-2,4-dimethoxyphenyl}amino)-4-oxobutanoic acid
Authors:Lahiri, S., Otterbein, L.
Deposit date:2011-09-21
Release date:2011-10-19
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:In Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzae.
J.Biol.Chem., 286, 2011
4A3N
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CRYSTAL STRUCTURE OF HMG-BOX OF HUMAN SOX17
Descriptor:TRANSCRIPTION FACTOR SOX-17, ZINC ION
Authors:Gao, N., Gao, H., Qian, H., Si, S., Xie, Y.
Deposit date:2011-10-01
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA.
Protein Pept.Lett., 20, 2013
3U2D
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S. AUREUS GYRB ATPASE DOMAIN IN COMPLEX WITH SMALL MOLECULE INHIBITOR
Descriptor:DNA gyrase subunit B, 4-bromo-5-methyl-N-[1-(3-nitropyridin-2-yl)piperidin-4-yl]-1H-pyrrole-2-carboxamide, MAGNESIUM ION
Authors:Boriack-Sjodin, P.A., Prince, D.B., Eakin, A.E., Sherer, B.A.
Deposit date:2011-10-03
Release date:2012-01-11
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents.
Antimicrob.Agents Chemother., 56, 2012
3U2K
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S. AUREUS GYRB ATPASE DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR
Descriptor:DNA gyrase subunit B, 2-chloro-6-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)pyridine-4-carboxamide, MAGNESIUM ION
Authors:Boriack-Sjodin, P.A., Prince, D.B., Eakin, A.E., Sherer, B.A.
Deposit date:2011-10-03
Release date:2012-01-11
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents.
Antimicrob.Agents Chemother., 56, 2012
3UQ8
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STRUCTURE OF ADENYLATION DOMAIN OF HAEMOPHILUS INFLUENZAE DNA LIGASES BOUND TO NAD+ IN ADENYLATED STATE.
Descriptor:DNA ligase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE
Authors:Lahiri, S.D.
Deposit date:2011-11-19
Release date:2012-01-25
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure Guided Understanding of NAD(+) Recognition in Bacterial DNA Ligases.
Acs Chem.Biol., 7, 2012
4DDP
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CRYSTAL STRUCTURE OF BECLIN 1 EVOLUTIONARILY CONSERVED DOMAIN(ECD)
Descriptor:Beclin-1
Authors:Huang, W.J., Choi, W.Y., Wang, J.W., Shi, Y.G.
Deposit date:2012-01-19
Release date:2012-02-22
Method:X-RAY DIFFRACTION (1.547 Å)
Cite:Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
Cell Res., 2012
3J28
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (12.9 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J29
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (14 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2A
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2014-10-22
Method:ELECTRON MICROSCOPY (13.1 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2B
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2C
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA head domain, 16S rRNA body domain
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (13.2 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2D
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-06
Method:ELECTRON MICROSCOPY (18.700001 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2E
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-06
Method:ELECTRON MICROSCOPY (15.3 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
3J2F
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-06
Method:ELECTRON MICROSCOPY (17.6 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.
Nucleic Acids Res., 41, 2013
3J2G
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-06
Method:ELECTRON MICROSCOPY (16.5 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.
Nucleic Acids Res., 41, 2013
3J2H
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DISSECTING THE IN VIVO ASSEMBLY OF THE 30S RIBOSOMAL SUBUNIT REVEALS THE ROLE OF RIMM
Descriptor:16S rRNA
Authors:Guo, Q., Goto, S., Chen, Y., Muto, A., Himeno, H., Deng, H., Lei, J., Gao, N.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2013-03-13
Method:ELECTRON MICROSCOPY (18.799999 Å)
Cite:Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.
Nucleic Acids Res., 41, 2013
4HQM
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THE CRYSTAL STRUCTURE OF QSRR-MENADIONE COMPLEX
Descriptor:QsrR protein, 2-methylnaphthalene-1,4-diol
Authors:Ji, Q., Zhang, L., Jones, M.B., Sun, F., Deng, X., Liang, H., Brugarolas, P., Gao, N., Peterson, S.N., Lan, L., Bae, T., He, C.
Deposit date:2012-10-25
Release date:2013-03-06
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J3D
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PSEUDOMONAS AERUGINOSA LPXC IN COMPLEX WITH A HYDROXAMATE INHIBITOR
Descriptor:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION, N~1~-hydroxy-N~5~-(3-hydroxypropyl)-N~2~-[4-(phenylethynyl)benzoyl]-L-glutamamide
Authors:Lahiri, S.
Deposit date:2013-02-05
Release date:2013-04-03
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploring the UDP pocket of LpxC through amino acid analogs.
Bioorg.Med.Chem.Lett., 23, 2013
3J3R
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2014-10-22
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
3J3S
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2015-01-21
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013