Author results

2GVX
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STRUCTURE OF DIISOPROPYL FLUOROPHOSPHATASE (DFPASE), MUTANT D229N / N175D
Descriptor:diisopropyl fluorophosphatase, CALCIUM ION
Authors:Blum, M.-M., Lohr, F., Richardt, A., Ruterjans, H., Chen, J.C.-H.
Deposit date:2006-05-03
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of a Designed Substrate Analogue to Diisopropyl Fluorophosphatase: Implications for the Phosphotriesterase Mechanism
J.Am.Chem.Soc., 128, 2006
1EX4
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HIV-1 INTEGRASE CATALYTIC CORE AND C-TERMINAL DOMAIN
Descriptor:INTEGRASE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE
Authors:Chen, J.C.-H., Krucinski, J., Miercke, L.J.W., Finer-Moore, J.S., Tang, A.H., Leavitt, A.D., Stroud, R.M.
Deposit date:2000-04-28
Release date:2000-06-07
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EXQ
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CRYSTAL STRUCTURE OF THE HIV-1 INTEGRASE CATALYTIC CORE DOMAIN
Descriptor:POL POLYPROTEIN, CADMIUM ION, CHLORIDE ION, ...
Authors:Chen, J.C.-H., Krucinski, J., Miercke, L.J.W., Finer-Moore, J.S., Tang, A.H., Leavitt, A.D., Stroud, R.M.
Deposit date:2000-05-03
Release date:2000-11-03
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding.
Proc.Natl.Acad.Sci.USA, 97, 2000
2BCE
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CHOLESTEROL ESTERASE FROM BOS TAURUS
Descriptor:CHOLESTEROL ESTERASE
Authors:Chen, J.C.-H., Miercke, L.J.W., Krucinski, J., Starr, J.R., Saenz, G., Wang, X., Spilburg, C.A., Lange, L.G., Ellsworth, J.L., Stroud, R.M.
Deposit date:1998-01-28
Release date:1999-02-02
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of bovine pancreatic cholesterol esterase at 1.6 A: novel structural features involved in lipase activation.
Biochemistry, 37, 1998
3HLH
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DIISOPROPYL FLUOROPHOSPHATASE (DFPASE), ACTIVE SITE MUTANTS
Descriptor:Diisopropyl-fluorophosphatase, CALCIUM ION
Authors:Chen, J.C.-H., Blum, M.-M.
Deposit date:2009-05-27
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design
J.Am.Chem.Soc., 131, 2009
3HLI
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DIISOPROPYL FLUOROPHOSPHATASE (DFPASE), ACTIVE SITE MUTANTS
Descriptor:Diisopropyl-fluorophosphatase, CALCIUM ION
Authors:Chen, J.C.-H., Blum, M.-M.
Deposit date:2009-05-27
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design
J.Am.Chem.Soc., 131, 2009
3LI3
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DIISOPROPYL FLUOROPHOSPHATASE (DFPASE), D121E MUTANT
Descriptor:Diisopropyl-fluorophosphatase, CALCIUM ION
Authors:Chen, J.C.-H.
Deposit date:2010-01-24
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural characterization of the catalytic calcium-binding site in diisopropyl fluorophosphatase (DFPase)-Comparison with related beta-propeller enzymes.
Chem.Biol.Interact, 187, 2010
3LI4
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DIISOPROPYL FLUOROPHOSPHATASE (DFPASE), N120D,N175D,D229N MUTANT
Descriptor:Diisopropyl-fluorophosphatase, CALCIUM ION
Authors:Chen, J.C.-H.
Deposit date:2010-01-24
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural characterization of the catalytic calcium-binding site in diisopropyl fluorophosphatase (DFPase)-Comparison with related beta-propeller enzymes.
Chem.Biol.Interact, 187, 2010
3LI5
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DIISOPROPYL FLUOROPHOSPHATASE (DFPASE), E21Q,N120D,N175D,D229N MUTANT
Descriptor:Diisopropyl-fluorophosphatase, CALCIUM ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Chen, J.C.-H.
Deposit date:2010-01-24
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Structural characterization of the catalytic calcium-binding site in diisopropyl fluorophosphatase (DFPase)-Comparison with related beta-propeller enzymes.
Chem.Biol.Interact, 187, 2010
3U7T
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ROOM TEMPERATURE ULTRA-HIGH RESOLUTION TIME-OF-FLIGHT NEUTRON AND X-RAY DIFFRACTION STUDIES OF H/D EXCHANGED CRAMBIN
Descriptor:Crambin
Authors:Chen, J.C.-H.
Deposit date:2011-10-14
Release date:2012-02-08
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:Room-temperature ultrahigh-resolution time-of-flight neutron and X-ray diffraction studies of H/D-exchanged crambin.
Acta Crystallogr.,Sect.F, 68, 2012
1KEZ
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CRYSTAL STRUCTURE OF THE MACROCYCLE-FORMING THIOESTERASE DOMAIN OF ERYTHROMYCIN POLYKETIDE SYNTHASE (DEBS TE)
Descriptor:ERYTHRONOLIDE SYNTHASE
Authors:Tsai, S.-C., Miercke, L.J.W., Krucinski, J., Gokhale, R., Chen, J.C.-H., Foster, P.G., Cane, D.E., Khosla, C., Stroud, R.M.
Deposit date:2001-11-19
Release date:2002-01-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel.
Proc.Natl.Acad.Sci.USA, 98, 2001
1OSF
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HUMAN HSP90 IN COMPLEX WITH 17-DESMETHOXY-17-N,N-DIMETHYLAMINOETHYLAMINO-GELDANAMYCIN
Descriptor:heat shock 90kDa protein 1, alpha; heat shock 90kD protein 1, alpha, ...
Authors:Jez, J.M., Chen, J.C.-H., Rastelli, G., Stroud, R.M., Santi, D.V.
Deposit date:2003-03-19
Release date:2003-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure and Molecular Modeling of 17-DMAG in Complex with Human Hsp90
Chem.Biol., 10, 2003
2NUB
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STRUCTURE OF AQUIFEX AEOLICUS ARGONUATE
Descriptor:Argonaute
Authors:Rashid, U.J., Paterok, D., Koglin, A., Gohlke, H., Piehler, J., Chen, J.C.-H.
Deposit date:2006-11-09
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Aquifex aeolicus argonaute highlights conformational flexibility of the PAZ domain as a potential regulator of RNA-induced silencing complex function.
J.Biol.Chem., 282, 2007
3BYC
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JOINT NEUTRON AND X-RAY STRUCTURE OF DIISOPROPYL FLUOROPHOSPHATASE. DEUTERIUM OCCUPANCIES ARE 1-Q, WHERE Q IS OCCUPANCY OF H
Descriptor:Diisopropyl-fluorophosphatase, CALCIUM ION
Authors:Blum, M.-M., Mustyakimov, M., Ruterjans, H., Schoenborn, B.P., Langan, P., Chen, J.C.-H.
Deposit date:2008-01-15
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å), NEUTRON DIFFRACTION
Cite:Rapid determination of hydrogen positions and protonation states of diisopropyl fluorophosphatase by joint neutron and X-ray diffraction refinement.
Proc.Natl.Acad.Sci.Usa, 106, 2009
3KGG
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X-RAY STRUCTURE OF PERDEUTERATED DIISOPROPYL FLUOROPHOSPHATASE (DFPASE): PERDEUTERATION OF PROTEINS FOR NEUTRON DIFFRACTION
Descriptor:Diisopropyl-fluorophosphatase, CALCIUM ION
Authors:Blum, M.-M., Tomanicek, S.J., John, H., Hanson, B.L., terjans, H.R., Schoenborn, B.P., Langan, P., Chen, J.C.-H.
Deposit date:2009-10-29
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): perdeuteration of proteins for neutron diffraction.
Acta Crystallogr.,Sect.F, 66, 2010
4FC1
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ULTRA-HIGH RESOLUTION NEUTRON STRUCTURE OF CRAMBIN AT ROOM-TEMPERATURE
Descriptor:Crambin
Authors:Kovalevsky, A.Y., Chen, J.C.-H.
Deposit date:2012-05-23
Release date:2012-09-19
Last modified:2018-06-06
Method:NEUTRON DIFFRACTION (1.1 Å)
Cite:Direct observation of hydrogen atom dynamics and interactions by ultrahigh resolution neutron protein crystallography.
Proc.Natl.Acad.Sci.USA, 109, 2012