Author results

1XFB
  • Download 1xfb
  • View 1xfb
Molmil generated image of 1xfb
HUMAN BRAIN FRUCTOSE 1,6-(BIS)PHOSPHATE ALDOLASE (C ISOZYME)
Descriptor:Aldolase C
Authors:Arakaki, T.L., Pezza, J.A., Cronin, M.A., Hopkins, C.E., Zimmer, D.B., Tolan, D.R., Allen, K.N.
Deposit date:2004-09-14
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function
Protein Sci., 13, 2004
2B4G
  • Download 2b4g
  • View 2b4g
Molmil generated image of 2b4g
DIHYDROOROTATE DEHYDROGENASE
Descriptor:dihydroorotate dehydrogenase, BROMIDE ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-23
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies
Mol.Microbiol., 68, 2008
2HQJ
  • Download 2hqj
  • View 2hqj
Molmil generated image of 2hqj
CYCLOPHILIN FROM LEISHMANIA MAJOR
Descriptor:Peptidyl-prolyl cis-trans isomerase, PHOSPHATE ION
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2006-07-18
Release date:2006-07-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cyclophilin from Leishmania major
To be Published
3C61
  • Download 3c61
  • View 3c61
Molmil generated image of 3c61
CRYSTAL STRUCTURE OF DIHYDROOROTATE DEHYDROGENASE FROM LEISHMANIA DONOVANI
Descriptor:Dihydroorotate dehydrogenase, CHLORIDE ION, AZIDE ION, ...
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2008-02-01
Release date:2008-02-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dihydroorotate dehydrogenase from Leishmania donovani.
To be Published
3CH7
  • Download 3ch7
  • View 3ch7
Molmil generated image of 3ch7
CRYSTAL STRUCTURE OF 6-PHOSPHOGLUCONOLACTONASE FROM LEISHMANIA BRAZILIENSIS
Descriptor:6-phosphogluconolactonase
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2008-03-07
Release date:2008-03-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:6-phosphogluconolactonase from Leishmania braziliensis.
to be published
3E15
  • Download 3e15
  • View 3e15
Molmil generated image of 3e15
6-PHOSPHOGLUCONOLACTONASE FROM PLASMODIUM VIVAX
Descriptor:Glucose-6-phosphate 1-dehydrogenase, CHLORIDE ION, POTASSIUM ION, ...
Authors:Arakaki, T.L., Merritt, E.A.
Deposit date:2008-08-01
Release date:2008-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:6-phosphogluconolactonase from Plasmodium vivax
To be Published
3E3P
  • Download 3e3p
  • View 3e3p
Molmil generated image of 3e3p
GLYCOGEN SYNTHASE KINASE FROM LEISHMANIA MAJOR
Descriptor:Protein kinase, putative Glycogen synthase kinase
Authors:Arakaki, T.L., Merritt, E.A.
Deposit date:2008-08-07
Release date:2008-08-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Glycogen synthase kinase from Leishmania major
To be Published
3FOC
  • Download 3foc
  • View 3foc
Molmil generated image of 3foc
TRYPTOPHANYL-TRNA SYNTHETASE FROM GIARDIA LAMBLIA
Descriptor:Tryptophanyl-tRNA synthetase, GLYCEROL, SULFATE ION
Authors:Arakaki, T.L., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2008-12-29
Release date:2009-01-13
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologs.
J.Struct.Biol., 171, 2010
3MEQ
  • Download 3meq
  • View 3meq
Molmil generated image of 3meq
CRYSTAL STRUCTURE OF ALCOHOL DEHYDROGENASE FROM BRUCELLA MELITENSIS
Descriptor:Alcohol dehydrogenase, zinc-containing, ZINC ION, ...
Authors:Arakaki, T.L., Staker, B.L., Gardberg, A., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of alcohol dehydrogenase from Brucella melitensis
To be Published
3HRI
  • Download 3hri
  • View 3hri
Molmil generated image of 3hri
HISTIDYL-TRNA SYNTHETASE (APO) FROM TRYPANOSOMA BRUCEI
Descriptor:Histidyl-tRNA synthetase
Authors:Arakaki, T.L., Merritt, E.A., Larson, E.T., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-06-09
Release date:2009-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs.
J.Mol.Biol., 397, 2010
3HRK
  • Download 3hrk
  • View 3hrk
Molmil generated image of 3hrk
HISTIDYL-TRNA SYNTHETASE FROM TRYPANOSOMA CRUZI (HISTIDYL-ADENYLATE COMPLEX)
Descriptor:Histidyl-tRNA synthetase, HISTIDYL-ADENOSINE MONOPHOSPHATE, CHLORIDE ION
Authors:Arakaki, T.L., Merritt, E.A., Larson, E.T., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-06-09
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs.
J.Mol.Biol., 397, 2010
3BWC
  • Download 3bwc
  • View 3bwc
Molmil generated image of 3bwc
CRYSTAL STRUCTURE OF SPERMIDINE SYNTHASE FROM TRYPANOSOMA CRUZI IN COMPLEX WITH SAM AT 2.3 A RESOLUTION
Descriptor:Spermidine synthase, S-ADENOSYLMETHIONINE, BETA-MERCAPTOETHANOL
Authors:Bosch, J., Arakaki, T.L., Le Trong, I., Merritt, E.A., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2008-01-09
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of spermidine synthase from Trypanosoma cruzi.
To be Published
2A0M
  • Download 2a0m
  • View 2a0m
Molmil generated image of 2a0m
ARGINASE SUPERFAMILY PROTEIN FROM TRYPANOSOMA CRUZI
Descriptor:ARGINASE SUPERFAMILY PROTEIN, CHLORIDE ION
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-16
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Structural genomics of pathogenic protozoa: an overview.
Methods Mol.Biol., 426, 2008
2AR1
  • Download 2ar1
  • View 2ar1
Molmil generated image of 2ar1
STRUCTURE OF HYPOTHETICAL PROTEIN FROM LEISHMANIA MAJOR
Descriptor:hypothetical protein, GLYCEROL
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-08-18
Release date:2005-08-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major.
Acta Crystallogr.,Sect.F, 62, 2006
2GZQ
  • Download 2gzq
  • View 2gzq
Molmil generated image of 2gzq
PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN FROM PLASMODIUM VIVAX
Descriptor:Phosphatidylethanolamine-binding protein
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2006-05-11
Release date:2006-05-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix
Acta Crystallogr.,Sect.F, 63, 2007
3CSS
  • Download 3css
  • View 3css
Molmil generated image of 3css
CRYSTAL STRUCTURE OF 6-PHOSPHOGLUCONOLACTONASE FROM LEISHMANIA GUYANENSIS
Descriptor:6-phosphogluconolactonase, PHOSPHATE ION
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2008-04-10
Release date:2008-04-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Optimal description of a protein structure in terms of multiple groups undergoing TLS motion.
Acta Crystallogr.,Sect.D, 62, 2006
3I3F
  • Download 3i3f
  • View 3i3f
Molmil generated image of 3i3f
HYPOTHETICAL PROTEIN FROM GIARDIA LAMBLIA GL50803_14299
Descriptor:Hypothetical protein, PENTANOIC ACID, BUTANOIC ACID
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-06-30
Release date:2009-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Hypothetical protein from Giardia lamblia GL50803_14299
To be Published
3OUI
  • Download 3oui
  • View 3oui
Molmil generated image of 3oui
PHD2-R717 WITH 40787422
Descriptor:Egl nine homolog 1, ACETATE ION, FE (II) ION, ...
Authors:Arakaki, T.L., Kim, H.
Deposit date:2010-09-14
Release date:2010-12-01
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues.
ACS Med Chem Lett, 1, 2010
3U0A
  • Download 3u0a
  • View 3u0a
Molmil generated image of 3u0a
CRYSTAL STRUCTURE OF AN ACYL-COA THIOESTERASE II TESB2 FROM MYCOBACTERIUM MARINUM
Descriptor:Acyl-CoA thioesterase II TesB2, SULFATE ION, GLYCEROL, ...
Authors:Arakaki, T.L., Staker, B.L., Clifton, M.C., Sankaran, B., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-09-28
Release date:2011-10-05
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3U0B
  • Download 3u0b
  • View 3u0b
Molmil generated image of 3u0b
CRYSTAL STRUCTURE OF AN OXIDOREDUCTASE FROM MYCOBACTERIUM SMEGMATIS
Descriptor:Oxidoreductase, short chain dehydrogenase/reductase family protein, SODIUM ION
Authors:Arakaki, T.L., Staker, B.L., Clifton, M.C., Abendroth, J., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-09-28
Release date:2011-10-05
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3HV0
  • Download 3hv0
  • View 3hv0
Molmil generated image of 3hv0
TRYPTOPHANYL-TRNA SYNTHETASE FROM CRYPTOSPORIDIUM PARVUM
Descriptor:Tryptophanyl-tRNA synthetase, TRYPTOPHAN
Authors:Arakaki, T., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-06-15
Release date:2009-06-30
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.
Mol.Biochem.Parasitol., 177, 2011
3HZR
  • Download 3hzr
  • View 3hzr
Molmil generated image of 3hzr
TRYPTOPHANYL-TRNA SYNTHETASE HOMOLOG FROM ENTAMOEBA HISTOLYTICA
Descriptor:Tryptophanyl-tRNA synthetase
Authors:Arakaki, T., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-06-24
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.
Mol.Biochem.Parasitol., 177, 2011
3I05
  • Download 3i05
  • View 3i05
Molmil generated image of 3i05
TRYPTOPHANYL-TRNA SYNTHETASE FROM TRYPANOSOMA BRUCEI
Descriptor:Tryptophanyl-tRNA synthetase
Authors:Arakaki, T., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-06-24
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.
Mol.Biochem.Parasitol., 177, 2011
3I7F
  • Download 3i7f
  • View 3i7f
Molmil generated image of 3i7f
ASPARTYL TRNA SYNTHETASE FROM ENTAMOEBA HISTOLYTICA
Descriptor:Aspartyl-tRNA synthetase
Authors:Arakaki, T., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-07-08
Release date:2009-07-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica.
Mol.Biochem.Parasitol., 169, 2010
3BJE
  • Download 3bje
  • View 3bje
Molmil generated image of 3bje
CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI NUCLEOSIDE PHOSPHORYLASE SHOWS URIDINE PHOSPHORYLASE ACTIVITY
Descriptor:Nucleoside phosphorylase, putative, RIBOSE-1-PHOSPHATE, ...
Authors:Larson, E.T., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2007-12-03
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:The Crystal Structure and Activity of a Putative Trypanosomal Nucleoside Phosphorylase Reveal It to be a Homodimeric Uridine Phosphorylase
J.Mol.Biol., 396, 2010
<123>