Author results

2PY5
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PHI29 DNA POLYMERASE COMPLEXED WITH SINGLE-STRANDED DNA
Descriptor:5'-d(GGACTTT)-3', DNA polymerase, 1,2-ETHANEDIOL
Authors:Berman, A.J., Kamtekar, S., Goodman, J.L., Lazaro, J.M., de Vega, M., Blanco, L., Salas, M., Steitz, T.A.
Deposit date:2007-05-15
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2PYJ
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PHI29 DNA POLYMERASE COMPLEXED WITH PRIMER-TEMPLATE DNA AND INCOMING NUCLEOTIDE SUBSTRATES (TERNARY COMPLEX)
Descriptor:5'-d(GACTGCTTA(DOC)-3', 5'-d(ACACGTAAGCAGTC)-3', DNA polymerase, ...
Authors:Berman, A.J., Kamtekar, S., Goodman, J.L., Lazaro, J.M., de Vega, M., Blanco, L., Salas, M., Steitz, T.A.
Deposit date:2007-05-16
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2PYL
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PHI29 DNA POLYMERASE COMPLEXED WITH PRIMER-TEMPLATE DNA AND INCOMING NUCLEOTIDE SUBSTRATES (TERNARY COMPLEX)
Descriptor:5'-d(GACTGCTTAC(2DA))-3', 5'-d(CTGACGAATGTACA)-3', DNA polymerase, ...
Authors:Berman, A.J., Kamtekar, S., Goodman, J.L., Lazaro, J.M., de Vega, M., Blanco, L., Salas, M., Steitz, T.A.
Deposit date:2007-05-16
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2PZS
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PHI29 DNA POLYMERASE COMPLEXED WITH PRIMER-TEMPLATE DNA (POST-TRANSLOCATION BINARY COMPLEX)
Descriptor:5'-d(GACTGCTTAC)-3', 5'-d(CTAACACGTAAGCAGTC)-3', DNA polymerase
Authors:Berman, A.J., Kamtekar, S., Goodman, J.L., Lazaro, J.M., de Vega, M., Blanco, L., Salas, M., Steitz, T.A.
Deposit date:2007-05-18
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2Q6T
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CRYSTAL STRUCTURE OF THE THERMUS AQUATICUS DNAB MONOMER
Descriptor:DnaB replication fork helicase, SULFATE ION
Authors:Bailey, S., Eliason, W.K., Steitz, T.A.
Deposit date:2007-06-05
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of the Thermus aquaticus DnaB helicase monomer.
Nucleic Acids Res., 35, 2007
2Q7E
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THE STRUCTURE OF PYRROLYSYL-TRNA SYNTHETASE BOUND TO AN ATP ANALOGUE
Descriptor:Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q7G
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PYRROLYSINE TRNA SYNTHETASE BOUND TO A PYRROLYSINE ANALOGUE (CYC) AND ATP
Descriptor:Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q7H
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PYRROLYSYL-TRNA SYNTHETASE BOUND TO ADENYLATED PYRROLYSINE AND PYROPHOSPHATE
Descriptor:Pyrrolysyl-tRNA synthetase, 1,2-ETHANEDIOL, (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, ...
Authors:Kavran, J.M., Steitz, T.A.
Deposit date:2007-06-06
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R6A
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CRYSTAL FORM BH1
Descriptor:Replicative helicase, DnaG Primase, Helicase Binding Domain, ...
Authors:Bailey, S., Eliason, W.K., Steitz, T.A.
Deposit date:2007-09-05
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase
Science, 318, 2007
2R6C
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CRYSTAL FORM BH2
Descriptor:Replicative helicase, DnaG Primase, Helicase Binding Domain
Authors:Bailey, S., Eliason, W.K., Steitz, T.A.
Deposit date:2007-09-05
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase
Science, 318, 2007
2R6D
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CRYSTAL FORM B1
Descriptor:Replicative helicase
Authors:Bailey, S., Eliason, W.K., Steitz, T.A.
Deposit date:2007-09-05
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase
Science, 318, 2007
2R6E
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CRYSTAL FORM B2
Descriptor:Replicative helicase, SULFATE ION
Authors:Bailey, S., Eliason, W.K., Steitz, T.A.
Deposit date:2007-09-05
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5.019 Å)
Cite:Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase
Science, 318, 2007
397D
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A 1.3 A RESOLUTION CRYSTAL STRUCTURE OF THE HIV-1 TRANS-ACTIVATION RESPONSE REGION RNA STEM REVEALS A METAL ION-DEPENDENT BULGE CONFORMATION
Descriptor:RNA (5'-R(*GP*GP*CP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*UP*CP*UP*CP*UP*GP*GP*CP*CP*C)-3'), CALCIUM ION
Authors:Ippolito, J.A., Steitz, T.A.
Deposit date:1998-04-30
Release date:1998-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation.
Proc.Natl.Acad.Sci.USA, 95, 1998
3CB4
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THE CRYSTAL STRUCTURE OF LEPA
Descriptor:GTP-binding protein lepA
Authors:Evans, R.N., Blaha, G., Bailey, S., Steitz, T.A.
Deposit date:2008-02-21
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of LepA, the ribosomal back translocase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3CMA
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THE STRUCTURE OF CCA AND CCA-PHE-CAP-BIO BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI
Descriptor:50S ribosomal protein L2P, 50S ribosomal protein L3P, 50S ribosomal protein L4P, ...
Authors:Simonovic, M., Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3CME
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THE STRUCTURE OF CA AND CCA-PHE-CAP-BIO BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI
Descriptor:50S ribosomal protein L2P, 50S ribosomal protein L3P, 50S ribosomal protein L4P, ...
Authors:Simonovic, M., Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3CPW
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THE STRUCTURE OF THE ANTIBIOTIC LINEZOLID BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI
Descriptor:23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, 50S ribosomal protein L2P, ...
Authors:Ippolito, J.A., Kanyo, Z.K., Wang, D., Franceschi, F.J., Moore, P.B., Steitz, T.A., Duffy, E.M.
Deposit date:2008-04-01
Release date:2008-07-22
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
J.Med.Chem., 51, 2008
3E0D
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INSIGHTS INTO THE REPLISOME FROM THE CRYSTRAL STRUCTURE OF THE TERNARY COMPLEX OF THE EUBACTERIAL DNA POLYMERASE III ALPHA-SUBUNIT
Descriptor:DNA substrate template strand, DNA substrate primer strand, DNA polymerase III subunit alpha, ...
Authors:Wing, R.A., Bailey, S., Steitz, T.A.
Deposit date:2008-07-31
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III alpha-Subunit.
J.Mol.Biol., 382, 2008
3E2E
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CRYSTAL STRUCTURE OF AN INTERMEDIATE COMPLEX OF T7 RNAP AND 7NT OF RNA
Descriptor:DNA-directed RNA polymerase, RNA (5'-R(*GP*GP*GP*AP*GP*UP*G)-3'), DNA (31-MER), ...
Authors:Durniak, K.J., Bailey, S., Steitz, T.A.
Deposit date:2008-08-05
Release date:2008-11-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of a transcribing t7 RNA polymerase in transition from initiation to elongation
Science, 322, 2008
3E3J
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CRYSTAL STRUCTURE OF AN INTERMEDIATE COMPLEX OF T7 RNAP AND 8NT OF RNA
Descriptor:DNA-directed RNA polymerase, DNA (28-MER), DNA (5'-D(*DTP*DAP*DAP*DTP*DAP*DCP*DGP*DAP*DCP*DTP*DCP*DAP*DCP*DTP*DAP*DTP*DAP*DTP*DTP*DTP*DCP*DTP*DGP*DCP*DCP*DAP*DAP*DAP*DCP*DGP*DGP*DC)-3'), ...
Authors:Durniak, K.J., Bailey, S., Steitz, T.A.
Deposit date:2008-08-07
Release date:2008-11-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (6.7 Å)
Cite:The structure of a transcribing t7 RNA polymerase in transition from initiation to elongation
Science, 322, 2008
3EDU
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CRYSTAL STRUCTURE OF THE ANKYRIN-BINDING DOMAIN OF HUMAN ERYTHROID SPECTRIN
Descriptor:Spectrin beta chain, erythrocyte
Authors:Simonovic, M., Stabach, P., Simonovic, I., Steitz, T.A., Morrow, J.S.
Deposit date:2008-09-03
Release date:2009-02-10
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of the ankyrin-binding site of {beta}-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties
Blood, 113, 2009
3G4S
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CO-CRYSTAL STRUCTURE OF TIAMULIN BOUND TO THE LARGE RIBOSOMAL SUBUNIT
Descriptor:23S ribosomal RNA, 50S ribosomal protein L2P, 50S ribosomal protein L3P, ...
Authors:Gurel, G., Blaha, G., Moore, P.B., Steitz, T.A.
Deposit date:2009-02-04
Release date:2009-04-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
J.Mol.Biol., 389, 2009
3G6E
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CO-CRYSTAL STRUCTURE OF HOMOHARRINGTONINE BOUND TO THE LARGE RIBOSOMAL SUBUNIT
Descriptor:23S ribosomal RNA, 50S ribosomal protein L2P, 50S ribosomal protein L3P, ...
Authors:Gurel, G., Blaha, G., Moore, P.B., Steitz, T.A.
Deposit date:2009-02-06
Release date:2009-04-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
J.Mol.Biol., 389, 2009
3G71
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CO-CRYSTAL STRUCTURE OF BRUCEANTIN BOUND TO THE LARGE RIBOSOMAL SUBUNIT
Descriptor:23S ribosomal RNA, 50S ribosomal protein L2P, 50S ribosomal protein L3P, ...
Authors:Gurel, G., Blaha, G., Moore, P.B., Steitz, T.A.
Deposit date:2009-02-09
Release date:2009-04-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
J.Mol.Biol., 389, 2009
3GNA
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CRYSTAL STRUCTURE OF THE RAG1 NONAMER-BINDING DOMAIN WITH DNA
Descriptor:V(D)J recombination-activating protein 1, 5'-D(*AP*CP*TP*TP*AP*AP*CP*AP*AP*AP*AP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*TP*TP*TP*TP*GP*TP*TP*AP*AP*G)-3'
Authors:Yin, F.F., Bailey, S., Innis, C.A., Steitz, T.A., Schatz, D.G.
Deposit date:2009-03-16
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis.
Nat.Struct.Mol.Biol., 16, 2009