Author results

1H1K
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THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Descriptor:RNA
Authors:Diprose, J.M., Grimes, J.M., Sutton, G.C., Burroughs, J.N., Meyer, A., Maan, S., Mertens, P.P.C., Stuart, D.I.
Deposit date:2002-07-17
Release date:2002-09-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (10 Å)
Cite:The Core of Bluetongue Virus Binds Double-Stranded RNA
J.Virol., 76, 2002
1HHS
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RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6
Descriptor:RNA-DIRECTED RNA POLYMERASE, MANGANESE (II) ION
Authors:Grimes, J.M., Butcher, S.J., Makeyev, E.V., Bamford, D.H., Stuart, D.I.
Deposit date:2000-12-28
Release date:2001-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1HHT
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RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6 PLUS TEMPLATE
Descriptor:DNA (5'-(*TP*TP*TP*CP*C)-3'), P2 PROTEIN, MANGANESE (II) ION
Authors:Grimes, J.M., Butcher, S.J., Makeyev, E.V., Bamford, D.H., Stuart, D.I.
Deposit date:2000-12-28
Release date:2001-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1HI0
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RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6 PLUS INITIATION COMPLEX
Descriptor:DNA (5'-(*TP*TP*TP*CP*C)-3'), P2 PROTEIN, MANGANESE (II) ION, ...
Authors:Grimes, J.M., Butcher, S.J., Makeyev, E.V., Bamford, D.H., Stuart, D.I.
Deposit date:2000-12-31
Release date:2001-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1HI1
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RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6 PLUS BOUND NTP
Descriptor:P2 PROTEIN, ADENOSINE-5'-TRIPHOSPHATE
Authors:Grimes, J.M., Butcher, S.J., Makeyev, E.V., Bamford, D.H., Stuart, D.I.
Deposit date:2001-01-01
Release date:2001-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1HI8
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RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6
Descriptor:P2 PROTEIN, MAGNESIUM ION
Authors:Grimes, J.M., Butcher, S.J., Makeyev, E.V., Bamford, D.H., Stuart, D.I.
Deposit date:2001-01-03
Release date:2001-03-27
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1MHE
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THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, BETA-2-MICROGLOBULIN, PEPTIDE (VMAPRTVLL), ...
Authors:O'Callaghan, C.A., Tormo, J., Willcox, B.E., Braud, V.B., Jakobsen, B.K., Stuart, D.I., Mcmichael, A.J., Bell, J.I., Jones, E.Y.
Deposit date:1998-08-24
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Mol.Cell, 1, 1998
1MU2
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CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE
Descriptor:HIV-2 RT, SULFATE ION, GLYCEROL
Authors:Ren, J., Bird, L.E., Chamberlain, P.P., Stewart-Jones, G.B., Stuart, D.I., Stammers, D.K.
Deposit date:2002-09-23
Release date:2002-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors
Proc.Natl.Acad.Sci.USA, 99, 2002
1QQP
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FOOT-AND-MOUTH DISEASE VIRUS/ OLIGOSACCHARIDE RECEPTOR COMPLEX.
Descriptor:PROTEIN (GENOME POLYPROTEIN), 2-O-sulfo-alpha-L-gulopyranuronic acid, N,O6-DISULFO-GLUCOSAMINE, ...
Authors:Fry, E.E., Lea, S.M., Jackson, T., Newman, J.W.I., Ellard, F.M., Blakemore, W.E., Abu-Ghazaleh, R., Samuel, A., King, A.M.Q., Stuart, D.I.
Deposit date:1999-05-20
Release date:1999-06-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.
EMBO J., 18, 1999
1VCA
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CRYSTAL STRUCTURE OF AN INTEGRIN-BINDING FRAGMENT OF VASCULAR CELL ADHESION MOLECULE-1 AT 1.8 ANGSTROMS RESOLUTION
Descriptor:HUMAN VASCULAR CELL ADHESION MOLECULE-1
Authors:Jones, E.Y., Harlos, K., Bottomley, M.J., Robinson, R.C., Driscoll, P.C., Edwards, R.M., Clements, J.M., Dudgeon, T.J., Stuart, D.I.
Deposit date:1995-03-21
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.
Nature, 373, 1995
2W2S
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STRUCTURE OF THE LAGOS BAT VIRUS MATRIX PROTEIN
Descriptor:MATRIX PROTEIN
Authors:Graham, S.C., Assenberg, R., Delmas, O., Verma, A., Gholami, A., Talbi, C., Owens, R.J., Stuart, D.I., Grimes, J.M., Bourhy, H.
Deposit date:2008-11-03
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Rhabdovirus Matrix Protein Structures Reveal a Novel Mode of Self-Association.
Plos Pathog., 4, 2008
2X7L
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IMPLICATIONS OF THE HIV-1 REV DIMER STRUCTURE AT 3.2A RESOLUTION FOR MULTIMERIC BINDING TO THE REV RESPONSE ELEMENT
Descriptor:FAB HEAVY CHAIN, FAB LIGHT CHAIN, PROTEIN REV
Authors:DiMattia, M.A., Watts, N.R., Stahl, S.J., Rader, C., Wingfield, P.T., Stuart, D.I., Steven, A.C., Grimes, J.M.
Deposit date:2010-03-01
Release date:2010-03-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Implications of the HIV-1 Rev Dimer Structure at 3. 2 A Resolution for Multimeric Binding to the Rev Response Element.
Proc.Natl.Acad.Sci.USA, 107, 2010
4CDQ
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP2
Descriptor:VP1, VP2, VP3, ...
Authors:DeColibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-05
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDU
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP3
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-06
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDW
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP4
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-06
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDX
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP12
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-07
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CEW
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR ALD
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-12
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CEY
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR NLD
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-12
Release date:2014-02-12
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4UOI
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UNEXPECTED STRUCTURE FOR THE N-TERMINAL DOMAIN OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E1
Descriptor:GENOME POLYPROTEIN, N-ACETYL-D-GLUCOSAMINE
Authors:El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.
Deposit date:2014-06-04
Release date:2014-08-20
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Unexpected Structure for the N-Terminal Domain of Hepatitis C Virus Envelope Glycoprotein E1
Acta Crystallogr.,Sect.D, 70, 2014
5MUV
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ATOMIC STRUCTURE FITTED INTO A LOCALIZED RECONSTRUCTION OF BACTERIOPHAGE PHI6 PACKAGING HEXAMER P4
Descriptor:Packaging enzyme P4, CALCIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Sun, Z., El Omari, K., Sun, X., Ilca, S., Kotecha, A., Stuart, D.I., Poranen, M.M., Huiskonen, J.T.
Deposit date:2017-01-14
Release date:2017-03-22
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.
Nat Commun, 8, 2017
5MUW
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ATOMIC STRUCTURE OF P4 PACKAGING ENZYME FITTED INTO A LOCALIZED RECONSTRUCTION OF BACTERIOPHAGE PHI6 VERTEX
Descriptor:Packaging enzyme P4, CALCIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Sun, Z., El Omari, K., Sun, X., Ilca, S., Kotecha, A., Stuart, D.I., Poranen, M.M., Huiskonen, J.T.
Deposit date:2017-01-14
Release date:2017-03-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.
Nat Commun, 8, 2017
6F6I
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CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH PAROXETINE
Descriptor:Envelope glycoprotein,GP,GP1, Envelope glycoprotein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ren, J., Zhao, Y., Fry, E.E., Stuart, D.I.
Deposit date:2017-12-05
Release date:2018-01-03
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection.
J. Med. Chem., 61, 2018
6F6N
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CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH SERTRALINE
Descriptor:Envelope glycoprotein,Envelope glycoprotein,GP1, Envelope glycoprotein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ren, J., Zhao, Y., Fry, E.E., Stuart, D.I.
Deposit date:2017-12-05
Release date:2018-01-03
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection.
J. Med. Chem., 61, 2018
6F6S
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CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH BENZTROPINE
Descriptor:Envelope glycoprotein,Envelope glycoprotein,GP1, Envelope glycoprotein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ren, J., Zhao, Y., Fry, E.E., Stuart, D.I.
Deposit date:2017-12-06
Release date:2018-01-03
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection.
J. Med. Chem., 61, 2018
1ECW
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CRYSTAL STRUCTURE OF SIMIAN IMMUNODEFICIENCY VIRUS MATRIX ANTIGEN (SIV MA) AT 293K.
Descriptor:GAG POLYPROTEIN, ISOPROPYL ALCOHOL
Authors:Rao, Z., Belyaev, A., Fry, E., Roy, P., Jones, I.M., Stuart, D.I.
Deposit date:2000-01-26
Release date:2000-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of SIV matrix antigen and implications for virus assembly.
Nature, 378, 1995