Author results

4LOG
  • Download 4log
  • View 4log
Molmil generated image of 4log
THE CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR PNR LIGAND BINDING DOMAIN FUSED WITH MBP
Descriptor:Maltose ABC transporter periplasmic protein and NR2E3 protein chimeric construct
Authors:Tan, M.E., Zhou, X.E., Soon, F.-F., Li, X., Li, J., Yong, E.-L., Melcher, K., Xu, H.E.
Deposit date:2013-07-12
Release date:2013-10-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Domain Reveals a Dimeric Auto-Repressed Conformation.
Plos One, 8, 2013
4LRH
  • Download 4lrh
  • View 4lrh
Molmil generated image of 4lrh
CRYSTAL STRUCTURE OF HUMAN FOLATE RECEPTOR ALPHA IN COMPLEX WITH FOLIC ACID
Descriptor:Folate receptor alpha, FOLIC ACID, N-ACETYL-D-GLUCOSAMINE
Authors:Ke, J., Chen, C., Zhou, X.E., Yi, W., Brunzelle, J.S., Li, J., Young, E.-L., Xu, H.E., Melcher, K.
Deposit date:2013-07-19
Release date:2013-07-31
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for molecular recognition of folic acid by folate receptors.
Nature, 500, 2013
4ME2
  • Download 4me2
  • View 4me2
Molmil generated image of 4me2
CRYSTAL STRUCTURE OF THA8 PROTEIN FROM BRACHYPODIUM DISTACHYON
Descriptor:Uncharacterized protein
Authors:Ke, J., Chen, R.Z., Ban, T., Brunzelle, J.S., Gu, X., Melcher, K., Xu, H.E.
Deposit date:2013-08-24
Release date:2013-10-30
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
4MY2
  • Download 4my2
  • View 4my2
Molmil generated image of 4my2
CRYSTAL STRUCTURE OF NORRIN IN FUSION WITH MALTOSE BINDING PROTEIN
Descriptor:Maltose-binding periplasmic protein, Norrin fusion protein, MALTOSE
Authors:Ke, J., Jurecky, C., Chen, C., Gu, X., Parker, N., Williams, B.O., Melcher, K., Xu, H.E.
Deposit date:2013-09-27
Release date:2013-11-13
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex.
Genes Dev., 27, 2013
4N2Q
  • Download 4n2q
  • View 4n2q
Molmil generated image of 4n2q
CRYSTAL STRUCTURE OF THA8 IN COMPLEX WITH ZM4 RNA
Descriptor:THA8 RNA binding protein, RNA (5'-R(*AP*AP*GP*AP*AP*GP*AP*AP*AP*UP*UP*GP*G)-3')
Authors:Ke, J., Chen, R.Z., Ban, T., Zhou, X.E., Gu, X., Brunzelle, J.S., Zhu, J.K., Melcher, K., Xu, H.E.
Deposit date:2013-10-06
Release date:2013-10-30
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
4N2S
  • Download 4n2s
  • View 4n2s
Molmil generated image of 4n2s
CRYSTAL STRUCTURE OF THA8 IN COMPLEX WITH ZM1A-6 RNA
Descriptor:THA8 RNA binding protein, Zm1a-6 RNA
Authors:Ke, J., Chen, R.Z., Ban, T., Zhou, X.E., Gu, X., Brunzelle, J.S., Zhu, J.K., Melcher, K., Xu, H.E.
Deposit date:2013-10-06
Release date:2013-10-30
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
4NUF
  • Download 4nuf
  • View 4nuf
Molmil generated image of 4nuf
CRYSTAL STRUCTURE OF SHP/EID1
Descriptor:Maltose ABC transporter periplasmic protein, Nuclear receptor subfamily 0 group B member 2 chimeric construct, EID1 peptide, ...
Authors:Zhi, X., Zhou, X.E., He, Y., Zechner, C., Suino-Powell, K.M., Kliewer, S.A., Melcher, K., Mangelsdorf, D.J., Xu, H.E.
Deposit date:2013-12-03
Release date:2014-01-29
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into gene repression by the orphan nuclear receptor SHP.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RED
  • Download 4red
  • View 4red
Molmil generated image of 4red
CRYSTAL STRUCTURE OF HUMAN AMPK ALPHA1 KD-AID WITH K43A MUTATION
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1
Authors:Zhou, X.E., Ke, J., Li, X., Wang, L., Gu, X., de Waal, P.W., Tan, M.H.E., Wang, D., Wu, D., Xu, H.E., Melcher, K.
Deposit date:2014-09-22
Release date:2014-12-10
Last modified:2015-03-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis of AMPK regulation by adenine nucleotides and glycogen.
Cell Res., 25, 2015
4RER
  • Download 4rer
  • View 4rer
Molmil generated image of 4rer
CRYSTAL STRUCTURE OF THE PHOSPHORYLATED HUMAN ALPHA1 BETA2 GAMMA1 HOLO-AMPK COMPLEX BOUND TO AMP AND CYCLODEXTRIN
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Zhou, X.E., Ke, J., Li, X., Wang, L., Gu, X., de Waal, P.W., Tan, M.H.E., Wang, D., Wu, D., Xu, H.E., Melcher, K.
Deposit date:2014-09-23
Release date:2014-12-10
Last modified:2015-03-11
Method:X-RAY DIFFRACTION (4.047 Å)
Cite:Structural basis of AMPK regulation by adenine nucleotides and glycogen.
Cell Res., 25, 2015
4REW
  • Download 4rew
  • View 4rew
Molmil generated image of 4rew
CRYSTAL STRUCTURE OF THE NON-PHOSPHORYLATED HUMAN ALPHA1 BETA2 GAMMA1 HOLO-AMPK COMPLEX
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Zhou, X.E., Ke, J., Li, X., Wang, L., Gu, X., de Waal, P.W., Tan, M.H.E., Wang, D., Wu, D., Xu, H.E., Melcher, K.
Deposit date:2014-09-24
Release date:2014-12-10
Last modified:2015-03-11
Method:X-RAY DIFFRACTION (4.58 Å)
Cite:Structural basis of AMPK regulation by adenine nucleotides and glycogen.
Cell Res., 25, 2015
4RQW
  • Download 4rqw
  • View 4rqw
Molmil generated image of 4rqw
CRYSTAL STRUCTURE OF MYC3 N-TERMINAL JAZ-BINDING DOMAIN [44-238] FROM ARABIDOPSIS
Descriptor:Transcription factor MYC3, CALCIUM ION
Authors:Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J., Zhou, M., Xu, H.E., Melcher, K., He, S.Y.
Deposit date:2014-11-05
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RRU
  • Download 4rru
  • View 4rru
Molmil generated image of 4rru
MYC3 N-TERMINAL JAZ-BINDING DOMAIN[5-242] FROM ARABIDOPSIS
Descriptor:Transcription factor MYC3, CALCIUM ION
Authors:Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J.S., Zhou, M., Xu, H.E., Melcher, K., He, S.Y.
Deposit date:2014-11-06
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RS9
  • Download 4rs9
  • View 4rs9
Molmil generated image of 4rs9
STRUCTURE OF MYC3 N-TERMINAL JAZ-BINDING DOMAIN [44-238] IN COMPLEX WITH JAS MOTIF OF JAZ9
Descriptor:Transcription factor MYC3, Protein TIFY 7
Authors:Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J.S., Zhou, M., Xu, H.E., Melcher, K., He, S.Y.
Deposit date:2014-11-07
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YWC
  • Download 4ywc
  • View 4ywc
Molmil generated image of 4ywc
CRYSTAL STRUCTURE OF MYC3(5-242) FRAGMENT IN COMPLEX WITH JAZ9(218-239) PEPTIDE
Descriptor:Transcription factor MYC3, Protein TIFY 7
Authors:Ke, J., Zhang, F., Brunzelle, J.S., Xu, H.E., Melcher, K., He, S.Y.
Deposit date:2015-03-20
Release date:2015-08-05
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YZ6
  • Download 4yz6
  • View 4yz6
Molmil generated image of 4yz6
CRYSTAL STRUCTURE OF MYC3[44-238] FROM ARABIDOPSIS IN COMPLEX WITH JAZ1 PEPTIDE [200-221]
Descriptor:Transcription factor MYC3, Protein TIFY 10A
Authors:Ke, J., Zhang, F., Brunzelle, J., Xu, H.E., Melcher, K., HE, S.Y.
Deposit date:2015-03-24
Release date:2015-08-05
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4ZHE
  • Download 4zhe
  • View 4zhe
Molmil generated image of 4zhe
CRYSTAL STRUCTURE OF THE SEMET SUBSTITUTED TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) FROM RICE
Descriptor:ASPR2 protein
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C6Q
  • Download 5c6q
  • View 5c6q
Molmil generated image of 5c6q
CRYSTAL STRUCTURE OF THE APO TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) FROM RICE
Descriptor:ASPR2 protein, ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-06-23
Release date:2015-08-05
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.251 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C6V
  • Download 5c6v
  • View 5c6v
Molmil generated image of 5c6v
CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS NINJA PEPTIDE
Descriptor:ASPR2 protein, AFP homolog 2
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-06-23
Release date:2015-08-05
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7E
  • Download 5c7e
  • View 5c7e
Molmil generated image of 5c7e
CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS IAA10 PEPTIDE
Descriptor:ASPR2 protein, Auxin-responsive protein IAA10, ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7F
  • Download 5c7f
  • View 5c7f
Molmil generated image of 5c7f
CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS IAA1 PEPTIDE
Descriptor:ASPR2 protein, Auxin-responsive protein IAA1, ZINC ION
Authors:Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5CM4
  • Download 5cm4
  • View 5cm4
Molmil generated image of 5cm4
CRYSTAL STRUCTURE OF HUMAN FRIZZLED 4 CYSTEINE-RICH DOMAIN (CRD)
Descriptor:Frizzled-4, N-ACETYL-D-GLUCOSAMINE
Authors:Ke, J., Parker, N., Gu, X., Zhang, C., Melcher, K., Xu, H.E.
Deposit date:2015-07-16
Release date:2015-08-12
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of the Norrin-Frizzled 4 interaction.
Cell Res., 25, 2015
5DGY
  • Download 5dgy
  • View 5dgy
Molmil generated image of 5dgy
CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO VISUAL ARRESTIN
Descriptor:Endolysin,Rhodopsin,S-arrestin
Authors:Zhou, X.E., Gao, X., Kang, Y., He, Y., de Waal, P.W., Suino-Powell, K.M., Wang, M., Melcher, K., Xu, H.E.
Deposit date:2015-08-28
Release date:2016-03-23
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (7.7 Å)
Cite:X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex.
Sci Data, 3, 2016
5DJ5
  • Download 5dj5
  • View 5dj5
Molmil generated image of 5dj5
CRYSTAL STRUCTURE OF RICE DWARF14 IN COMPLEX WITH SYNTHETIC STRIGOLACTONE GR24
Descriptor:Probable strigolactone esterase D14, (3E,3aR,8bS)-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylidene)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one
Authors:Zhou, X.E., Zhao, L.-H., Yi, W., Wu, Z.-S., Liu, Y., Kang, Y., Hou, L., de Waal, P.W., Li, S., Jiang, Y., Melcher, K., Xu, H.E.
Deposit date:2015-09-01
Release date:2015-10-28
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3.
Cell Res., 25, 2015
5TDH
  • Download 5tdh
  • View 5tdh
Molmil generated image of 5tdh
THE CRYSTAL STRUCTURE OF THE DOMINANT NEGATIVE MUTANT G PROTEIN ALPHA(I)-1-BETA-1-GAMMA-2 G203A/A326S
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Liu, P., Jia, M.-Z., Zhou, X.E., de Waal, P.W., Dickson, B.M., Liu, B., Hou, L., Yin, Y.-T., Kang, Y.-Y., Shi, Y., Melcher, K., Xu, H.E., Jiang, Y.
Deposit date:2016-09-19
Release date:2016-11-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
Acta Pharmacol.Sin., 37, 2016
5UWG
  • Download 5uwg
  • View 5uwg
Molmil generated image of 5uwg
THE CRYSTAL STRUCTURE OF FZ4-CRD IN COMPLEX WITH PALMITOLEIC ACID
Descriptor:Frizzled-4, PALMITOLEIC ACID, N-ACETYL-D-GLUCOSAMINE
Authors:Ke, J., DeBruine, Z.J., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
Deposit date:2017-02-21
Release date:2017-06-14
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization.
Genes Dev., 31, 2017