4ME2 | | CRYSTAL STRUCTURE OF THA8 PROTEIN FROM BRACHYPODIUM DISTACHYON | | Descriptor: | Uncharacterized protein | | Authors: | Ke, J., Chen, R.Z., Ban, T., Brunzelle, J.S., Gu, X., Melcher, K., Xu, H.E. | | Deposit date: | 2013-08-24 | | Release date: | 2013-10-30 | | Last modified: | 2013-12-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
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4MY2 | | CRYSTAL STRUCTURE OF NORRIN IN FUSION WITH MALTOSE BINDING PROTEIN | | Descriptor: | Maltose-binding periplasmic protein, Norrin fusion protein, MALTOSE | | Authors: | Ke, J., Jurecky, C., Chen, C., Gu, X., Parker, N., Williams, B.O., Melcher, K., Xu, H.E. | | Deposit date: | 2013-09-27 | | Release date: | 2013-11-13 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex.
Genes Dev., 27, 2013
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4N2Q | | CRYSTAL STRUCTURE OF THA8 IN COMPLEX WITH ZM4 RNA | | Descriptor: | THA8 RNA binding protein, RNA (5'-R(*AP*AP*GP*AP*AP*GP*AP*AP*AP*UP*UP*GP*G)-3') | | Authors: | Ke, J., Chen, R.Z., Ban, T., Zhou, X.E., Gu, X., Brunzelle, J.S., Zhu, J.K., Melcher, K., Xu, H.E. | | Deposit date: | 2013-10-06 | | Release date: | 2013-10-30 | | Last modified: | 2014-01-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
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4N2S | | CRYSTAL STRUCTURE OF THA8 IN COMPLEX WITH ZM1A-6 RNA | | Descriptor: | THA8 RNA binding protein, Zm1a-6 RNA | | Authors: | Ke, J., Chen, R.Z., Ban, T., Zhou, X.E., Gu, X., Brunzelle, J.S., Zhu, J.K., Melcher, K., Xu, H.E. | | Deposit date: | 2013-10-06 | | Release date: | 2013-10-30 | | Last modified: | 2014-01-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
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4NUF | | CRYSTAL STRUCTURE OF SHP/EID1 | | Descriptor: | Maltose ABC transporter periplasmic protein, Nuclear receptor subfamily 0 group B member 2 chimeric construct, EID1 peptide, ... | | Authors: | Zhi, X., Zhou, X.E., He, Y., Zechner, C., Suino-Powell, K.M., Kliewer, S.A., Melcher, K., Mangelsdorf, D.J., Xu, H.E. | | Deposit date: | 2013-12-03 | | Release date: | 2014-01-29 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insights into gene repression by the orphan nuclear receptor SHP.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4RED | | CRYSTAL STRUCTURE OF HUMAN AMPK ALPHA1 KD-AID WITH K43A MUTATION | | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | | Authors: | Zhou, X.E., Ke, J., Li, X., Wang, L., Gu, X., de Waal, P.W., Tan, M.H.E., Wang, D., Wu, D., Xu, H.E., Melcher, K. | | Deposit date: | 2014-09-22 | | Release date: | 2014-12-10 | | Last modified: | 2015-03-11 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural basis of AMPK regulation by adenine nucleotides and glycogen.
Cell Res., 25, 2015
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4RER | | CRYSTAL STRUCTURE OF THE PHOSPHORYLATED HUMAN ALPHA1 BETA2 GAMMA1 HOLO-AMPK COMPLEX BOUND TO AMP AND CYCLODEXTRIN | | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | | Authors: | Zhou, X.E., Ke, J., Li, X., Wang, L., Gu, X., de Waal, P.W., Tan, M.H.E., Wang, D., Wu, D., Xu, H.E., Melcher, K. | | Deposit date: | 2014-09-23 | | Release date: | 2014-12-10 | | Last modified: | 2015-03-11 | | Method: | X-RAY DIFFRACTION (4.047 Å) | | Cite: | Structural basis of AMPK regulation by adenine nucleotides and glycogen.
Cell Res., 25, 2015
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4REW | | CRYSTAL STRUCTURE OF THE NON-PHOSPHORYLATED HUMAN ALPHA1 BETA2 GAMMA1 HOLO-AMPK COMPLEX | | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | | Authors: | Zhou, X.E., Ke, J., Li, X., Wang, L., Gu, X., de Waal, P.W., Tan, M.H.E., Wang, D., Wu, D., Xu, H.E., Melcher, K. | | Deposit date: | 2014-09-24 | | Release date: | 2014-12-10 | | Last modified: | 2015-03-11 | | Method: | X-RAY DIFFRACTION (4.58 Å) | | Cite: | Structural basis of AMPK regulation by adenine nucleotides and glycogen.
Cell Res., 25, 2015
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4RQW | | CRYSTAL STRUCTURE OF MYC3 N-TERMINAL JAZ-BINDING DOMAIN [44-238] FROM ARABIDOPSIS | | Descriptor: | Transcription factor MYC3, CALCIUM ION | | Authors: | Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J., Zhou, M., Xu, H.E., Melcher, K., He, S.Y. | | Deposit date: | 2014-11-05 | | Release date: | 2015-08-12 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
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4RRU | | MYC3 N-TERMINAL JAZ-BINDING DOMAIN[5-242] FROM ARABIDOPSIS | | Descriptor: | Transcription factor MYC3, CALCIUM ION | | Authors: | Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J.S., Zhou, M., Xu, H.E., Melcher, K., He, S.Y. | | Deposit date: | 2014-11-06 | | Release date: | 2015-08-12 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
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4RS9 | | STRUCTURE OF MYC3 N-TERMINAL JAZ-BINDING DOMAIN [44-238] IN COMPLEX WITH JAS MOTIF OF JAZ9 | | Descriptor: | Transcription factor MYC3, Protein TIFY 7 | | Authors: | Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J.S., Zhou, M., Xu, H.E., Melcher, K., He, S.Y. | | Deposit date: | 2014-11-07 | | Release date: | 2015-08-12 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
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4YWC | | CRYSTAL STRUCTURE OF MYC3(5-242) FRAGMENT IN COMPLEX WITH JAZ9(218-239) PEPTIDE | | Descriptor: | Transcription factor MYC3, Protein TIFY 7 | | Authors: | Ke, J., Zhang, F., Brunzelle, J.S., Xu, H.E., Melcher, K., He, S.Y. | | Deposit date: | 2015-03-20 | | Release date: | 2015-08-05 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
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4YZ6 | | CRYSTAL STRUCTURE OF MYC3[44-238] FROM ARABIDOPSIS IN COMPLEX WITH JAZ1 PEPTIDE [200-221] | | Descriptor: | Transcription factor MYC3, Protein TIFY 10A | | Authors: | Ke, J., Zhang, F., Brunzelle, J., Xu, H.E., Melcher, K., HE, S.Y. | | Deposit date: | 2015-03-24 | | Release date: | 2015-08-05 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
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4ZHE | | CRYSTAL STRUCTURE OF THE SEMET SUBSTITUTED TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) FROM RICE | | Descriptor: | ASPR2 protein | | Authors: | Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K. | | Deposit date: | 2015-04-24 | | Release date: | 2015-08-05 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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5C6Q | | CRYSTAL STRUCTURE OF THE APO TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) FROM RICE | | Descriptor: | ASPR2 protein, ZINC ION | | Authors: | Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K. | | Deposit date: | 2015-06-23 | | Release date: | 2015-08-05 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (3.251 Å) | | Cite: | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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5C6V | | CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS NINJA PEPTIDE | | Descriptor: | ASPR2 protein, AFP homolog 2 | | Authors: | Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K. | | Deposit date: | 2015-06-23 | | Release date: | 2015-08-05 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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5C7E | | CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS IAA10 PEPTIDE | | Descriptor: | ASPR2 protein, Auxin-responsive protein IAA10, ZINC ION | | Authors: | Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K. | | Deposit date: | 2015-06-24 | | Release date: | 2015-08-05 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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5C7F | | CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL DOMAIN (1-209) IN COMPLEX WITH ARABIDOPSIS IAA1 PEPTIDE | | Descriptor: | ASPR2 protein, Auxin-responsive protein IAA1, ZINC ION | | Authors: | Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K. | | Deposit date: | 2015-06-24 | | Release date: | 2015-08-05 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
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5CM4 | | CRYSTAL STRUCTURE OF HUMAN FRIZZLED 4 CYSTEINE-RICH DOMAIN (CRD) | | Descriptor: | Frizzled-4, N-ACETYL-D-GLUCOSAMINE | | Authors: | Ke, J., Parker, N., Gu, X., Zhang, C., Melcher, K., Xu, H.E. | | Deposit date: | 2015-07-16 | | Release date: | 2015-08-12 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis of the Norrin-Frizzled 4 interaction.
Cell Res., 25, 2015
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5DGY | | CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO VISUAL ARRESTIN | | Descriptor: | Endolysin,Rhodopsin,S-arrestin | | Authors: | Zhou, X.E., Gao, X., Kang, Y., He, Y., de Waal, P.W., Suino-Powell, K.M., Wang, M., Melcher, K., Xu, H.E. | | Deposit date: | 2015-08-28 | | Release date: | 2016-03-23 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (7.7 Å) | | Cite: | X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex.
Sci Data, 3, 2016
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5DJ5 | | CRYSTAL STRUCTURE OF RICE DWARF14 IN COMPLEX WITH SYNTHETIC STRIGOLACTONE GR24 | | Descriptor: | Probable strigolactone esterase D14, (3E,3aR,8bS)-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylidene)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one | | Authors: | Zhou, X.E., Zhao, L.-H., Yi, W., Wu, Z.-S., Liu, Y., Kang, Y., Hou, L., de Waal, P.W., Li, S., Jiang, Y., Melcher, K., Xu, H.E. | | Deposit date: | 2015-09-01 | | Release date: | 2015-10-28 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3.
Cell Res., 25, 2015
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5TDH | | THE CRYSTAL STRUCTURE OF THE DOMINANT NEGATIVE MUTANT G PROTEIN ALPHA(I)-1-BETA-1-GAMMA-2 G203A/A326S | | Descriptor: | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Liu, P., Jia, M.-Z., Zhou, X.E., de Waal, P.W., Dickson, B.M., Liu, B., Hou, L., Yin, Y.-T., Kang, Y.-Y., Shi, Y., Melcher, K., Xu, H.E., Jiang, Y. | | Deposit date: | 2016-09-19 | | Release date: | 2016-11-09 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
Acta Pharmacol.Sin., 37, 2016
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5UWG | | THE CRYSTAL STRUCTURE OF FZ4-CRD IN COMPLEX WITH PALMITOLEIC ACID | | Descriptor: | Frizzled-4, PALMITOLEIC ACID, N-ACETYL-D-GLUCOSAMINE | | Authors: | Ke, J., DeBruine, Z.J., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K. | | Deposit date: | 2017-02-21 | | Release date: | 2017-06-14 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization.
Genes Dev., 31, 2017
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5V54 | | CRYSTAL STRUCTURE OF 5-HT1B RECEPTOR IN COMPLEX WITH METHIOTHEPIN | | Descriptor: | 5-hydroxytryptamine receptor 1B,OB-1 fused 5-HT1b receptor,5-hydroxytryptamine receptor 1B, 1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine | | Authors: | Yin, W.C., Zhou, X.E., Yang, D., de Waal, P., Wang, M.T., Dai, A., Cai, X., Huang, C.Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.W., Xu, H.E., Jiang, Y. | | Deposit date: | 2017-03-13 | | Release date: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | A common antagonistic mechanism for class A GPCRs revealed by the structure of the human 5-HT1B serotonin receptor bound to an antagonist
Cell Discov, 2018
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6C9F | | AMP-ACTIVATED PROTEIN KINASE BOUND TO PHARMACOLOGICAL ACTIVATOR R734 | | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1,5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | | Authors: | Yan, Y., Zhou, X.E., Novick, S., Shaw, S.J., Li, Y., Hitoshi, Y., Brunzelle, J.S., Griffin, P.R., Xu, H.E., Melcher, K. | | Deposit date: | 2018-01-26 | | Release date: | 2018-11-28 | | Last modified: | 2019-04-17 | | Method: | X-RAY DIFFRACTION (2.924 Å) | | Cite: | Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.
J. Biol. Chem., 294, 2019
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