7U6P

Structure of an intellectual disability-associated ornithine decarboxylase variant G84R

Summary for 7U6P

• Entry DOI: 10.2210/pdb7u6p/pdb
• Descriptor: Ornithine decarboxylase, PHOSPHATE ION (3 entities in total)
• Functional Keywords: ornithine decarboxylase, intellectual disability-associated variant, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 94873.45

Authors

Zhou, X.E.,Schultz, C.R.,Powell, K.S.,Henrickson, A.,Lamp, J.,Brunzelle, J.S.,Demeler, B.,Vega, I.E.,Bachmann, A.S.,Melcher, K. (deposition date: 2022-03-04, release date: 2022-10-19, Last modification date: 2023-10-18)

• Primary citation: Zhou, X.E.,Schultz, C.R.,Suino Powell, K.,Henrickson, A.,Lamp, J.,Brunzelle, J.S.,Demeler, B.,Vega, I.E.,Bachmann, A.S.,Melcher, K.; Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R.; Acs Omega, 7:34665-34675, 2022; PubMed: 36188294; DOI: 10.1021/acsomega.2c04702

Experimental method

X-RAY DIFFRACTION (2.35 Å)