Author results

4IH3
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2.5 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF OF HUMAN 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE IN COMPLEX WITH DIPICOLINIC ACID
Descriptor:2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, ZINC ION, PYRIDINE-2,6-DICARBOXYLIC ACID
Authors:Huo, L., Liu, A.
Deposit date:2012-12-18
Release date:2014-05-21
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.493 Å)
Cite:Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling.
Proteins, 83, 2015
4OU2
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A 2.15 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF E268A 2-AMINOMUCONATE 6-SEMIALDEHYDE DEHYDROGENASE CATALYTIC INTERMEDIATE FROM PSEUDOMONAS FLUORESCENS
Descriptor:2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ...
Authors:Huo, L., Liu, A.
Deposit date:2014-02-14
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action.
Nat Commun, 6, 2015
4OUB
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A 2.20 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF E268A 2-AMINOMUCAONATE 6-SEMIALDEHYDE DEHYDROGENASE CATALYTIC INTERMEDIATE FROM PSEUDOMONAS FLUORESCENS
Descriptor:2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ...
Authors:Huo, L., Liu, A.
Deposit date:2014-02-15
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action.
Nat Commun, 6, 2015
5WP2
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1.44 ANGSTROM CRYSTAL STRUCTURE OF CYP121 FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH SUBSTRATE AND CN
Descriptor:Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, ...
Authors:Fielding, A., Dornevil, K., Liu, A.
Deposit date:2017-08-03
Release date:2018-05-30
Method:X-RAY DIFFRACTION (1.439 Å)
Cite:Probing Ligand Exchange in the P450 Enzyme CYP121 from Mycobacterium tuberculosis: Dynamic Equilibrium of the Distal Heme Ligand as a Function of pH and Temperature.
J. Am. Chem. Soc., 139, 2017
1QJK
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METALLOTHIONEIN MTA FROM SEA URCHIN (ALPHA DOMAIN)
Descriptor:METALLOTHIONEIN, CADMIUM ION
Authors:Riek, R., Precheur, B., Wang, Y., Mackay, E.A., Wider, G., Guntert, P., Liu, A., Kaegi, J.H.R., Wuthrich, K.
Deposit date:1999-06-24
Release date:1999-08-31
Last modified:2019-01-16
Method:SOLUTION NMR
Cite:NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA.
J. Mol. Biol., 291, 1999
1QJL
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METALLOTHIONEIN MTA FROM SEA URCHIN (BETA DOMAIN)
Descriptor:METALLOTHIONEIN, CADMIUM ION
Authors:Riek, R., Precheur, B., Wang, Y., Mackay, E.A., Wider, G., Guntert, P., Liu, A., Kaegi, J.H.R., Wuthrich, K.
Deposit date:1999-06-24
Release date:1999-08-31
Last modified:2019-01-16
Method:SOLUTION NMR
Cite:NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA.
J. Mol. Biol., 291, 1999
1QLX
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HUMAN PRION PROTEIN
Descriptor:PRION PROTEIN
Authors:Zahn, R., Liu, A., Luhrs, T., Wuthrich, K.
Deposit date:1999-09-17
Release date:1999-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
1QLZ
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HUMAN PRION PROTEIN
Descriptor:PRION PROTEIN
Authors:Zahn, R., Liu, A., Luhrs, T., Wuthrich, K.
Deposit date:1999-09-20
Release date:1999-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
1QM0
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HUMAN PRION PROTEIN FRAGMENT 90-230
Descriptor:PRION PROTEIN
Authors:Zahn, R., Liu, A., Luhrs, T., Wuthrich, K.
Deposit date:1999-09-20
Release date:1999-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
1QM1
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HUMAN PRION PROTEIN FRAGMENT 90-230
Descriptor:PRION PROTEIN
Authors:Zahn, R., Liu, A., Luhrs, T., Wuthrich, K.
Deposit date:1999-09-20
Release date:1999-12-16
Last modified:2011-12-07
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Human Prion Protein.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QM2
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HUMAN PRION PROTEIN FRAGMENT 121-230
Descriptor:PRION PROTEIN
Authors:Zahn, R., Liu, A., Luhrs, T., Wuthrich, K.
Deposit date:1999-09-20
Release date:1999-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
1QM3
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HUMAN PRION PROTEIN FRAGMENT 121-230
Descriptor:PRION PROTEIN
Authors:Zahn, R., Liu, A., Luhrs, T., Wuthrich, K.
Deposit date:1999-09-20
Release date:1999-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
2HBV
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CRYSTAL STRUCTURE OF ALPHA-AMINO-BETA-CARBOXYMUCONATE-EPSILON-SEMIALDEHYDE-DECARBOXYLASE (ACMSD)
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, ZINC ION, MAGNESIUM ION
Authors:Martynowski, D., Eyobo, Y., Li, T., Yang, K., Liu, A., Zhang, H.
Deposit date:2006-06-14
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of alpha-Amino-beta-carboxymuconate-epsilon-semialdehyde Decarboxylase: Insight into the Active Site and Catalytic Mechanism of a Novel Decarboxylation Reaction.
Biochemistry, 45, 2006
2HBX
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CRYSTAL STRUCTURE OF ALPHA-AMINO-BETA-CARBOXYMUCONATE-EPSILON-SEMIALDEHYDE-DECARBOXYLASE (ACMSD)
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, COBALT (II) ION
Authors:Martynowski, D., Eyobo, Y., Li, T., Yang, K., Liu, A., Zhang, H.
Deposit date:2006-06-14
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of alpha-Amino-beta-carboxymuconate-epsilon-semialdehyde Decarboxylase: Insight into the Active Site and Catalytic Mechanism of a Novel Decarboxylation Reaction.
Biochemistry, 45, 2006
3FZ2
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CRYSTAL STRUCTURE OF THE TAIL TERMINATOR PROTEIN FROM PHAGE LAMBDA (GPU-D74A)
Descriptor:Minor tail protein U, SULFATE ION
Authors:Pell, L.G., Liu, A., Edmonds, E., Donaldson, L.W., Howell, P.L., Davidson, A.R.
Deposit date:2009-01-23
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The X-ray crystal structure of the phage lambda tail terminator protein reveals the biologically relevant hexameric ring structure and demonstrates a conserved mechanism of tail termination among diverse long-tailed phages.
J.Mol.Biol., 389, 2009
3FZB
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CRYSTAL STRUCTURE OF THE TAIL TERMINATOR PROTEIN FROM PHAGE LAMBDA (GPU-WT)
Descriptor:Minor tail protein U, SULFATE ION
Authors:Pell, L.G., Liu, A., Edmonds, E., Donaldson, L.W., Howell, P.L., Davidson, A.R.
Deposit date:2009-01-24
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The X-ray crystal structure of the phage lambda tail terminator protein reveals the biologically relevant hexameric ring structure and demonstrates a conserved mechanism of tail termination among diverse long-tailed phages.
J.Mol.Biol., 389, 2009
4EPK
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EVIDENCE FOR A DUAL ROLE OF AN ACTIVE SITE HISTIDINE IN ALPHA-AMINO-BETA-CARBOXYMUCONATE-EPSILON-SEMIALDEHYDE DECARBOXYLASE
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, ZINC ION, MAGNESIUM ION
Authors:Huo, L., Fielding, A.J., Chen, Y., Li, T., Iwaki, H., Hosler, J.P., Chen, L., Hasegawa, Y., Que Jr., L., Liu, A.
Deposit date:2012-04-17
Release date:2012-08-22
Method:X-RAY DIFFRACTION (2.6009 Å)
Cite:Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
Biochemistry, 51, 2012
4ERA
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EVIDENCE FOR A DUAL ROLE OF AN ACTIVE SITE HISTIDINE IN ALPHA-AMINO-BETA-CARBOXYMUCONATE-EPSILON-SEMIALDEHYDE DECARBOXYLASE
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, COBALT (II) ION
Authors:Huo, L., Fielding, A.J., Chen, Y., Li, T., Iwaki, H., Hosler, J.P., Chen, L., Hasegawa, Y., Que Jr., L., Liu, A.
Deposit date:2012-04-19
Release date:2012-08-22
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
Biochemistry, 51, 2012
4ERG
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EVIDENCE FOR A DUAL ROLE OF AN ACTIVE SITE HISTIDINE IN ALPHA-AMINO-BETA-CARBOXYMUCONATE-EPSILON-SEMIALDEHYDE DECARBOXYLASE
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, FE (III) ION
Authors:Huo, L., Fielding, A.J., Chen, Y., Li, T., Iwaki, H., Hosler, J.P., Chen, L., Hasegawa, Y., Que Jr., L., Liu, A.
Deposit date:2012-04-20
Release date:2012-08-22
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
Biochemistry, 51, 2012
4ERI
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EVIDENCE FOR A DUAL ROLE OF AN ACTIVE SITE HISTIDINE IN ALPHA-AMINO-BETA-CARBOXYMUCONATE-EPSILON-SEMIALDEHYDE DECARBOXYLASE
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, ZINC ION, MAGNESIUM ION
Authors:Huo, L., Fielding, A.J., Chen, Y., Li, T., Iwaki, H., Hosler, J.P., Chen, L., Hasegawa, Y., Que Jr., L., Liu, A.
Deposit date:2012-04-20
Release date:2012-08-22
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.0006 Å)
Cite:Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
Biochemistry, 51, 2012
4IFK
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ARGININES 51 AND 239* FROM A NEIGHBORING SUBUNIT ARE ESSENTIAL FOR CATALYSIS IN A ZINC-DEPENDENT DECARBOXYLASE
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, MAGNESIUM ION, ZINC ION
Authors:Huo, L., Davis, I., Chen, L., Liu, A.
Deposit date:2012-12-14
Release date:2013-09-18
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.012 Å)
Cite:The power of two: arginine 51 and arginine 239* from a neighboring subunit are essential for catalysis in alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase.
J.Biol.Chem., 288, 2013
4IFO
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2.50 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF R51A 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE FROM PSEUDOMONAS FLUORESCENS
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, ZINC ION
Authors:Huo, L., Davis, I., Chen, L., Liu, A.
Deposit date:2012-12-14
Release date:2013-09-18
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The power of two: arginine 51 and arginine 239* from a neighboring subunit are essential for catalysis in alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase.
J.Biol.Chem., 288, 2013
4IFR
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2.40 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF R239A 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE FROM PSEUDOMONAS FLUORESCENS
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, ZINC ION
Authors:Huo, L., Davis, I., Chen, L., Liu, A.
Deposit date:2012-12-14
Release date:2013-09-18
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.391 Å)
Cite:The power of two: arginine 51 and arginine 239* from a neighboring subunit are essential for catalysis in alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase.
J.Biol.Chem., 288, 2013
4IG2
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1.80 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF R51A AND R239A HETERODIMER 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE FROM PSEUDOMONAS FLUORESCENS
Descriptor:2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, ZINC ION
Authors:Huo, L., Davis, I., Chen, L., Liu, A.
Deposit date:2012-12-15
Release date:2013-09-18
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The power of two: arginine 51 and arginine 239* from a neighboring subunit are essential for catalysis in alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase.
J.Biol.Chem., 288, 2013
4R52
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1.5 ANGSTROM CRYSTAL STRUCTURE OF 3-HYDROXYANTHRANILATE-3,4-DIOXYGENASE FROM CUPRIAVIDUS METALLIDURANS
Descriptor:3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Geng, J., Gumpper, R.H., Huo, L., Liu, A.
Deposit date:2014-08-20
Release date:2016-03-02
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:1.5 angstrom crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Cupriavidus metallidurans
To be Published