4K12

Structural Basis for Host Specificity of Factor H Binding by Streptococcus pneumoniae

Summary for 4K12

Entry DOI	10.2210/pdb4k12/pdb
Descriptor	Complement factor H, Choline binding protein A (3 entities in total)
Functional Keywords	protein-protein complex, complement-binding complex, immune system-choline binding protein complex, immune system/choline binding protein
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P08603
Total number of polymer chains	2
Total formula weight	17008.01
Authors	Liu, A.,Achila, D.,Banerjee, R.,Martinez-Hackert, E.,Li, Y.,Yan, H. (deposition date: 2013-04-04, release date: 2014-04-09, Last modification date: 2017-11-15)
Primary citation	Achila, D.,Liu, A.,Banerjee, R.,Li, Y.,Martinez-Hackert, E.,Zhang, J.R.,Yan, H. Structural determinants of host specificity of complement Factor H recruitment by Streptococcus pneumoniae. Biochem.J., 465:325-335, 2015 Cited by PubMed: 25330773 DOI: 10.1042/BJ20141069 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.079 Å)

Structure validation