6BPX

Crystal structure of cysteine-bound ferrous form of the matured Cl2-Tyr157 human cysteine dioxygenase

Summary for 6BPX

• Entry DOI: 10.2210/pdb6bpx/pdb
• Descriptor: Cysteine dioxygenase type 1, FE (II) ION, CYSTEINE, ... (6 entities in total)
• Functional Keywords: cysteine, cys-tyr cofactor, iron, unnatural amino acid, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 24032.40

Authors

Liu, A.,Li, J.,Shin, I. (deposition date: 2017-11-26, release date: 2018-07-04, Last modification date: 2023-10-04)

• Primary citation: Li, J.,Griffith, W.P.,Davis, I.,Shin, I.,Wang, J.,Li, F.,Wang, Y.,Wherritt, D.J.,Liu, A.; Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase.; Nat. Chem. Biol., 14:853-860, 2018; PubMed: 29942080; DOI: 10.1038/s41589-018-0085-5

Experimental method

X-RAY DIFFRACTION (2.15 Å)