Author results

4V8Z
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CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX
Descriptor:40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ...
Authors:Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
6FYX
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C1)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6FYY
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C2)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
2HKZ
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CRYSTAL STRUCTURE OF THE EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI IN COMPLEX WITH L-SERINE
Descriptor:Threonyl-tRNA synthetase, SERINE
Authors:Dwivedi, S., Kruparani, S.P., Sankaranarayanan, R.
Deposit date:2006-07-06
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Post-transfer editing mechanism of a D-aminoacyl-tRNA deacylase-like domain in threonyl-tRNA synthetase from archaea
Embo J., 25, 2006
4NBI
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D-AMINOACYL-TRNA DEACYLASE (DTD) FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH D-TYROSYL-3'-AMINOADENOSINE AT 1.86 ANGSTROM RESOLUTION
Descriptor:D-tyrosyl-tRNA(Tyr) deacylase, 3'-deoxy-3'-(D-tyrosylamino)adenosine, TRIETHYLENE GLYCOL
Authors:Ahmad, S., Routh, S.B., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2013-10-23
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Mechanism of chiral proofreading during translation of the genetic code.
Elife, 2, 2013
4NBJ
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D-AMINOACYL-TRNA DEACYLASE (DTD) FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH D-TYROSYL-3'-AMINOADENOSINE AT 2.20 ANGSTROM RESOLUTION
Descriptor:D-tyrosyl-tRNA(Tyr) deacylase, 3'-deoxy-3'-(D-tyrosylamino)adenosine
Authors:Ahmad, S., Routh, S.B., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2013-10-23
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of chiral proofreading during translation of the genetic code.
Elife, 2, 2013
4RR6
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA (SNAPSHOT 1)
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RR7
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA (SNAPSHOT 2)
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RR8
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA (SNAPSHOT 3)
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RR9
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA (SNAPSHOT 4)
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRA
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA (SNAPSHOT 1)
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRB
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA (SNAPSHOT 2)
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRC
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA (SNAPSHOT 3)
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRD
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA (SNAPSHOT 4)
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRF
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EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM METHANOCOCCUS JANNASCHII WITH L-SER3AA
Descriptor:Threonine--tRNA ligase, SERINE-3'-AMINOADENOSINE, CHLORIDE ION, ...
Authors:Ahmad, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRG
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EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM METHANOCOCCUS JANNASCHII WITH L-THR3AA
Descriptor:Threonine--tRNA ligase, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Ahmad, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRH
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K116M MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRI
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K116M MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRJ
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Y115A MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRK
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Y115A MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRL
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E129A MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE
Authors:Ahmad, S., Yerabham, A.S.K., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.965 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRM
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E129A MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION, ...
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
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