Author results

5C1Y
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 1
Descriptor:3C proteinase, N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-Nalpha-[(propan-2-yloxy)carbonyl]-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C20
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 2
Descriptor:3C proteinase, Nalpha-[(2-methylpropoxy)carbonyl]-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
1KXK
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CRYSTAL STRUCTURE OF A RNA MOLECULE CONTAINING DOMAIN 5 AND 6 OF THE YEAST AI5G GROUP II SELF-SPLICING INTRON
Descriptor:ai5g group II Self-splicing intron, MAGNESIUM ION
Authors:Zhang, L., Doudna, J.A.
Deposit date:2002-01-31
Release date:2002-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into group II intron catalysis and branch-site selection.
Science, 295, 2002
2C9P
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CU(I)CU(II)-COPC AT PH 4.5
Descriptor:COPPER RESISTANCE PROTEIN C, COPPER (II) ION, NITRATE ION
Authors:Zhang, L., Koay, M., Maher, M.J., Xiao, Z., Wedd, A.G.
Deposit date:2005-12-14
Release date:2006-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Intermolecular Transfer of Copper Ions from the Copc Protein of Pseudomonas Syringae. Crystal Structures of Fully Loaded Cu(I)Cu(II) Forms.
J.Am.Chem.Soc., 128, 2006
2C9Q
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CU(I)CU(II)-COPC AT PH 7.5
Descriptor:COPPER RESISTANCE PROTEIN C, COPPER (II) ION
Authors:Zhang, L., Koay, M., Maher, M.J., Xiao, Z., Wedd, A.G.
Deposit date:2005-12-14
Release date:2006-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Intermolecular Transfer of Copper Ions from the Copc Protein of Pseudomonas Syringae. Crystal Structures of Fully Loaded Cu(I)Cu(II) Forms.
J.Am.Chem.Soc., 128, 2006
2C9R
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APO-H91F COPC
Descriptor:COPPER RESISTANCE PROTEIN C, SODIUM ION
Authors:Zhang, L., Koay, M., Maher, M.J., Xiao, Z., Wedd, A.G.
Deposit date:2005-12-14
Release date:2006-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Intermolecular Transfer of Copper Ions from the Copc Protein of Pseudomonas Syringae. Crystal Structures of Fully Loaded Cu(I)Cu(II) Forms.
J.Am.Chem.Soc., 128, 2006
2FFK
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SOLUTION STRUCTURE OF THE COMPLEX BETWEEN POXVIRUS-ENCODED CC CHEMOKINE INHIBITOR VCCI AND HUMAN MIP-1BETA, MINIMIZED AVERAGE STRUCTURE
Descriptor:rabbitpox encoded CC chemokine inhibitor, Small inducible cytokine A4
Authors:Zhang, L.
Deposit date:2005-12-19
Release date:2006-08-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2FIN
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SOLUTION STRUCTURE OF THE COMPLEX BETWEEN POXVIRUS-ENCODED CC CHEMOKINE INHIBITOR VCCI AND HUMAN MIP-1BETA, ENSEMBLE STRUCTURE
Descriptor:rabbitpox encoded CC chemokine inhibitor, Small inducible cytokine A4
Authors:Zhang, L.
Deposit date:2005-12-29
Release date:2006-08-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2G0U
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SOLUTION STRUCTURE OF MONOMERIC BSAL, THE TYPE III SECRETION NEEDLE PROTEIN OF BURKHOLDERIA PSEUDOMALLEI
Descriptor:type III secretion system needle protein
Authors:Zhang, L., Wang, Y., Picking, W.L., Picking, W.D., De Guzman, R.N.
Deposit date:2006-02-13
Release date:2006-05-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Monomeric BsaL, the Type III Secretion Needle Protein of Burkholderia pseudomallei.
J.Mol.Biol., 359, 2006
2H1Y
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CRYSTAL STRUCTURE OF MALONYL-COA:ACYL CARRIER PROTEIN TRANSACYLASE (MCAT) FROM HELICOBACTER PYLORI
Descriptor:Malonyl coenzyme A-acyl carrier protein transacylase
Authors:Zhang, L., Liu, W., Shen, X., Jiang, H.
Deposit date:2006-05-17
Release date:2007-05-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Malonyl-CoA: acyl carrier protein transacylase from Helicobacter pylori: Crystal structure and its interaction with acyl carrier protein
Protein Sci., 16, 2007
2P87
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF C. ELEGANS PRE-MRNA SPLICING FACTOR PRP8
Descriptor:Pre-mRNA-splicing factor Prp8
Authors:Zhang, L., Shen, J., Guarnieri, M.T., Heroux, A., Yang, K., Zhao, R.
Deposit date:2007-03-21
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants
Protein Sci., 16, 2007
2P8R
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF C. ELEGANS PRE-MRNA SPLICING FACTOR PRP8 CARRYING R2303K MUTANT
Descriptor:Pre-mRNA-splicing factor Prp8
Authors:Zhang, L., Shen, J., Guarnieri, M.T., Heroux, A., Yang, K., Zhao, R.
Deposit date:2007-03-22
Release date:2007-05-22
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants
Protein Sci., 16, 2007
3HIB
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CRYSTAL STRUCTURE OF THE SECOND SEC63 DOMAIN OF YEAST BRR2
Descriptor:Pre-mRNA-splicing helicase BRR2
Authors:Zhang, L., Xu, T., Zhao, R.
Deposit date:2009-05-19
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2.
Nat.Struct.Mol.Biol., 16, 2009
3UO7
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CRYSTAL STRUCTURE OF HUMAN THYMINE DNA GLYCOSYLASE BOUND TO SUBSTRATE 5-CARBOXYLCYTOSINE
Descriptor:5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*AP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1CC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase
Authors:Zhang, L., He, C.
Deposit date:2011-11-16
Release date:2012-02-15
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Nat.Chem.Biol., 8, 2012
3UOB
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CRYSTAL STRUCTURE OF HUMAN THYMINE DNA GLYCOSYLASE BOUND TO SUBSTRATE ANALOG 2'-DEOXY-2'-BETA-FLUORO-CYTIDINE
Descriptor:5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1FC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase
Authors:Zhang, L., He, C.
Deposit date:2011-11-16
Release date:2012-02-15
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (3.011 Å)
Cite:Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Nat.Chem.Biol., 8, 2012
4IF2
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STRUCTURE OF THE PHOSPHOTRIESTERASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Phosphotriesterase homology protein, ZINC ION
Authors:Zhang, L., Li, X., Rao, Z.H.
Deposit date:2012-12-13
Release date:2013-12-18
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:The crystal structure of the phosphotriesterase from M. tuberculosis, another member of phosphotriesterase-like lactonase family.
Biochem. Biophys. Res. Commun., 2019
4J0W
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STRUCTURE OF U3-55K
Descriptor:U3 small nucleolar RNA-interacting protein 2
Authors:Zhang, L., Lin, J., Ye, K.
Deposit date:2013-01-31
Release date:2013-06-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional analysis of the U3 snoRNA binding protein Rrp9.
Rna, 19, 2013
4J0X
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STRUCTURE OF RRP9
Descriptor:Ribosomal RNA-processing protein 9
Authors:Zhang, L., Lin, J., Ye, K.
Deposit date:2013-01-31
Release date:2013-06-05
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structural and functional analysis of the U3 snoRNA binding protein Rrp9.
Rna, 19, 2013
4NXL
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DIBENZOTHIOPHENE MONOOXYGENASE (DSZC) FROM RHODOCOCCUS ERYTHROPOLIS
Descriptor:DszC
Authors:Zhang, L., Duan, X., Li, X., Rao, Z.
Deposit date:2013-12-09
Release date:2014-07-23
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the stabilization of active, tetrameric DszC by its C-terminus.
Proteins, 82, 2014
5EO3
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CRYSTAL STRUCTURE OF PELOTA C TERMINAL DOMAIN FROM HUMAN
Descriptor:Protein pelota homolog
Authors:Zhang, L., Cai, Q., Lin, T.
Deposit date:2015-11-10
Release date:2016-11-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Purification, crystallization and crystallographic analysis of the Pelota C terminal domian from human
to be published
5MGY
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CRYSTAL STRUCTURE OF PSEUDOMONAS STUTZERI FLAVINYL TRANSFERASE APBE, APO FORM
Descriptor:FAD:protein FMN transferase, MAGNESIUM ION
Authors:Zhang, L., Trncik, C., Andrade, S.L.A., Einsle, O.
Deposit date:2016-11-22
Release date:2016-12-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The flavinyl transferase ApbE of Pseudomonas stutzeri matures the NosR protein required for nitrous oxide reduction.
Biochim. Biophys. Acta, 1858, 2016
5XD6
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CARK1 PHOSPHORYLATES ABA RECEPTORS
Descriptor:Protein kinase superfamily protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Zhang, L., Lou, Z.
Deposit date:2017-03-27
Release date:2018-04-04
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:CARK1 phosphorylates ABA receptors
To Be Published
6B8F
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CONTRACTED HUMAN HEAVY-CHAIN FERRITIN CRYSTAL-HYDROGEL HYBRID
Descriptor:Ferritin heavy chain, FE (III) ION, CALCIUM ION
Authors:Zhang, L., Bailey, J.B., Subramanian, R., Tezcan, F.A.
Deposit date:2017-10-07
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks.
Nature, 557, 2018
6B8G
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TWICE-CONTRACTED HUMAN HEAVY-CHAIN FERRITIN CRYSTAL-HYDROGEL HYBRID
Descriptor:Ferritin heavy chain, FE (III) ION, CALCIUM ION
Authors:Zhang, L., Bailey, J.B., Subramanian, R., Tezcan, F.A.
Deposit date:2017-10-07
Release date:2018-05-02
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks.
Nature, 557, 2018
6RKZ
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RECOMBINANT PSEUDOMONAS STUTZERI NITROUS OXIDE REDUCTASE, FORM II
Descriptor:Nitrous-oxide reductase, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, ...
Authors:Zhang, L., Wuest, A., Prasser, B., Mueller, C., Einsle, O.
Deposit date:2019-04-30
Release date:2019-06-26
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Functional assembly of nitrous oxide reductase provides insights into copper site maturation.
Proc.Natl.Acad.Sci.USA, 116, 2019