Author results

5J41
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GLUTATHIONE S-TRANSFERASE BOUND WITH HYDROLYZED PIPERLONGUMINE
分子名称:Glutathione S-transferase P, 3-(3,4,5-trimethoxyphenyl)propanoic acid, GLUTATHIONE, ...
著者Harshbarger, W., Gondi, S., Ficarro, S., Hunter, J., Udayakumar, D., Gurbani, D., Marto, J., Westover, K.
登録日2016-03-31
公開日2016-11-30
最終更新日2017-01-18
実験手法X-RAY DIFFRACTION (1.190354 Å)
主引用文献Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine.
J. Biol. Chem., 292, 2017
5E54
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TWO APO STRUCTURES OF THE ADENINE RIBOSWITCH APTAMER DOMAIN DETERMINED USING AN X-RAY FREE ELECTRON LASER
分子名称:Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain, MAGNESIUM ION
著者Stagno, J.R., Wang, Y.-X., Liu, Y., Bhandari, Y.R., Conrad, C.E., Nelson, G., Li, C., Wendel, D.R., White, T.A., Barty, A., Tuckey, R.A., Zatsepin, N.A., Grant, T.D., Fromme, P., Tan, K., Ji, X., Spence, J.C.H.
登録日2015-10-07
公開日2016-11-23
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
5SWD
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STRUCTURE OF THE ADENINE RIBOSWITCH APTAMER DOMAIN IN AN INTERMEDIATE-BOUND STATE
分子名称:Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain, ADENINE, ...
著者Stagno, J.R., Wang, Y.-X., Liu, Y., Bhandari, Y.R., Conrad, C.E., Nelson, G., Li, C., Wendel, D.R., White, T.A., Barty, A., Tuckey, R.A., Zatsepin, N.A., Grant, T.D., Fromme, P., Tan, K., Ji, X., Spence, J.C.H.
登録日2016-08-08
公開日2016-11-23
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
5SWE
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LIGAND-BOUND STRUCTURE OF ADENINE RIBOSWITCH APTAMER DOMAIN CONVERTED IN CRYSTAL FROM ITS LIGAND-FREE STATE USING LIGAND MIXING SERIAL FEMTOSECOND CRYSTALLOGRAPHY
分子名称:Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain, ADENINE
著者Stagno, J.R., Wang, Y.-X., Liu, Y., Bhandari, Y.R., Conrad, C.E., Nelson, G., Li, C., Wendel, D.R., White, T.A., Barty, A., Tuckey, R.A., Zatsepin, N.A., Grant, T.D., Fromme, P., Tan, K., Ji, X., Spence, J.C.H.
登録日2016-08-08
公開日2016-11-23
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
5LSI
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CRYSTAL STRUCTURE OF THE KINETOCHORE MIS12 COMPLEX HEAD2 SUBDOMAIN CONTAINING DSN1 AND NSL1 FRAGMENTS
分子名称:Kinetochore-associated protein DSN1 homolog, Kinetochore-associated protein NSL1 homolog, SULFATE ION
著者Vetter, I.R., Petrovic, A., Keller, J., Liu, Y.
登録日2016-09-02
公開日2016-11-16
最終更新日2016-12-07
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
Cell, 167, 2016
5LSJ
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CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C DELTA-HEAD2 COMPLEX
分子名称:Protein MIS12 homolog, Polyamine-modulated factor 1, Kinetochore-associated protein DSN1 homolog, ...
著者Vetter, I.R., Petrovic, A., Keller, J., Liu, Y.
登録日2016-09-02
公開日2016-11-16
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
Cell, 167, 2016
5LSK
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CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C COMPLEX
分子名称:Protein MIS12 homolog, Polyamine-modulated factor 1, Kinetochore-associated protein DSN1 homolog, ...
著者Vetter, I.R., Petrovic, A., Keller, J., Liu, Y.
登録日2016-09-02
公開日2016-11-16
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.502 Å)
主引用文献Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
Cell, 167, 2016
5EGN
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EST816 AS AN N-ACYL HOMOSERINE LACTONE DEGRADING ENZYME
分子名称:Esterase
著者Xie, W., Liu, X., Cao, L., Liu, Y.
登録日2015-10-27
公開日2016-11-02
実験手法X-RAY DIFFRACTION (2.636 Å)
主引用文献Est816 as an N-Acyl homoserine lactone degrading enzyme
To Be Published
5FWP
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ATOMIC CRYOEM STRUCTURE OF HSP90-CDC37-CDK4 COMPLEX
分子名称:HEAT SHOCK PROTEIN HSP 90 BETA, HSP90 CO-CHAPERONE CDC37, CYCLIN-DEPENDENT KINASE 4, ...
著者Verba, K.A., Wang, R.Y.R., Arakawa, A., Liu, Y., Yokoyama, S., Agard, D.A.
登録日2016-02-18
公開日2016-10-26
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
5EYI
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STRUCTURE OF PRRSV APO-NSP11 AT 2.16A
分子名称:Non-structural protein 11, SULFATE ION, CHLORIDE ION, ...
著者Zhang, M.F., Chen, Z.
登録日2015-11-25
公開日2016-10-12
最終更新日2017-01-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural Biology of the Arterivirus nsp11 Endoribonucleases.
J. Virol., 91, 2017
5HBZ
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STRUCTURE OF EAV NSP11 K170A MUTANT AT 3.10A
分子名称:Non-structural protein 11
著者Zhang, M.F., Chen, Z.Z.
登録日2016-01-04
公開日2016-10-12
最終更新日2017-01-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Biology of the Arterivirus nsp11 Endoribonucleases.
J. Virol., 91, 2017
5HC1
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STRUCTURE OF EAV NSP11 H141A MUTANT AT 3.10A
分子名称:Non-structural protein 11
著者Zhang, M.F., Chen, Z.Z.
登録日2016-01-04
公開日2016-10-12
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Biology of the Arterivirus nsp11 Endoribonucleases.
J. Virol., 91, 2017
5GS6
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FULL-LENGTH NS1 STRUCTURE OF ZIKA VIRUS FROM 2015 BRAZIL STRAIN
分子名称:NS1 of Zika virus from 2015 Brazil strain, N-ACETYL-D-GLUCOSAMINE
著者Xu, X.Y., Song, H., Qi, J.X., Shi, Y., Gao, G.F.
登録日2016-08-14
公開日2016-10-05
最終更新日2016-11-16
実験手法X-RAY DIFFRACTION (2.852 Å)
主引用文献Contribution of intertwined loop to membrane association revealed by Zika virus full-length NS1 structure
Embo J., 35, 2016
5JZC
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HELICAL FILAMENT
分子名称:DNA repair protein RAD51 homolog 1
著者Short, J., Liu, Y.
登録日2016-05-16
公開日2016-09-21
最終更新日2018-10-17
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Nucleic Acids Res., 44, 2016
5EB9
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CRYSTAL STRUCTURE OF CHICKEN CD8AA HOMODIMER
分子名称:CD8 alpha chain
著者Liu, Y.J., Qi, J.X., Xia, C.
登録日2015-10-18
公開日2016-09-14
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species.
Sci Rep, 6, 2016
5EBG
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CRYSTAL STRUCTURE OF BOVINE CD8AA HOMODIMER
分子名称:T-cell surface glycoprotein CD8 alpha chain
著者Liu, Y., Li, X., Zhang, N., Qi, J., Xia, C.
登録日2015-10-19
公開日2016-09-14
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species.
Sci Rep, 6, 2016
5EDX
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CRYSTAL STRUCTURE OF SWINE CD8AA HOMODIMER
分子名称:CD8 alpha antigen
著者Liu, Y.J., Qi, J.X., Zhang, N.Z., Xia, C.
登録日2015-10-22
公開日2016-09-14
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species.
Sci Rep, 6, 2016
5ISY
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CRYSTAL STRUCTURE OF NUDIX FAMILY PROTEIN WITH NAD
分子名称:NADH pyrophosphatase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Zhang, D., Guan, Z., Zou, T., Yin, P.
登録日2016-03-15
公開日2016-09-14
実験手法X-RAY DIFFRACTION (2.354 Å)
主引用文献Structural basis of prokaryotic NAD-RNA decapping by NudC
Cell Res., 26, 2016
5IXS
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LACTATE DEHYDROGENASE IN COMPLEX WITH HYDROXYLACTAM INHIBITOR COMPOUND 9: (6R)-3-[(2-CHLOROPHENYL)SULFANYL]-4-HYDROXY-6-(3-HYDROXYPHENYL)-6-(THIOPHEN-3-YL)-5,6-DIHYDROPYRIDIN-2(1H)-ONE
分子名称:L-lactate dehydrogenase A chain, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Ultsch, M., Eigenbrot, C.
登録日2016-03-23
公開日2016-09-14
最終更新日2016-11-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Acs Med.Chem.Lett., 7, 2016
5IXY
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LACTATE DEHYDROGENASE IN COMPLEX WITH HYDROXYLACTAM INHIBITOR COMPOUND 31: (2~{S})-5-(2-CHLOROPHENYL)SULFANYL-2-(4-MORPHOLIN-4-YLPHENYL)-4-OXIDANYL-2-THIOPHEN-3-YL-1,3-DIHYDROPYRIDIN-6-ONE
分子名称:L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
著者Chen, Z., Eigenbrot, C.
登録日2016-03-23
公開日2016-09-14
最終更新日2016-11-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Acs Med.Chem.Lett., 7, 2016
5T1G
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CHROMO SHADOW DOMAIN OF CBX1 IN COMPLEX WITH A HISTONE PEPTIDE
分子名称:Chromobox protein homolog 1, Histone H3.1, UNKNOWN ATOM OR ION
著者Liu, Y., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2016-08-19
公開日2016-09-14
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献chromo shadow domain of CBX1 in complex with a histone peptide
To Be Published
5T1I
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CBX3 CHROMO SHADOW DOMAIN IN COMPLEX WITH HISTONE H3 PEPTIDE
分子名称:Chromobox protein homolog 3, Histone H3.1, UNKNOWN ATOM OR ION
著者Liu, Y., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2016-08-19
公開日2016-09-14
最終更新日2017-04-19
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.
J. Biol. Chem., 292, 2017
5I5N
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF MATRIX PROTEIN OF THOGOTO VIRUS AT ACIDIC PH.
分子名称:Matrix protein
著者Liu, Y., Liang, H., Yang, M.
登録日2016-02-15
公開日2016-08-17
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.418 Å)
主引用文献pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating
J.Gen.Virol., 97, 2016
5I5O
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF MATRIX PROTEIN OF THOGOTO VIRUS AT NEUTRAL PH.
分子名称:Matrix protein
著者Liu, Y., Liang, H., Yang, M.
登録日2016-02-15
公開日2016-08-17
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.682 Å)
主引用文献pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating
J.Gen.Virol., 97, 2016
5KR7
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KDM4C BOUND TO PYRAZOLO-PYRIMIDINE SCAFFOLD
分子名称:Lysine-specific demethylase 4C, FE (II) ION, ZINC ION, ...
著者Bellon, S.F., Poy, F., Setser, J.W.
登録日2016-07-07
公開日2016-08-17
最終更新日2016-08-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification of potent, selective KDM5 inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016